Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ingrid Koziollek-Drechsler"'
Autor:
Anna Weichert, Anna S. Besemer, Martina Liebl, Nadja Hellmann, Ingrid Koziollek-Drechsler, Philbert Ip, Heinz Decker, Janice Robertson, Avijit Chakrabartty, Christian Behl, Albrecht M. Clement
Publikováno v:
Neurobiology of Disease, Vol 62, Iss , Pp 479-488 (2014)
Mutations in the gene encoding Cu/Zn superoxide dismutase (SOD1) are responsible for a subset of amyotrophic lateral sclerosis cases presumably by the acquisition of as yet unknown toxic properties. Additional overexpression of wild-type SOD1 in muta
Externí odkaz:
https://doaj.org/article/5a7ad8d4cb184b3eb7720154d235762b
Autor:
Heidrun Witan, Philipp Gorlovoy, Ali M. Kaya, Ingrid Koziollek-Drechsler, Harald Neumann, Christian Behl, Albrecht M. Clement
Publikováno v:
Neurobiology of Disease, Vol 36, Iss 2, Pp 331-342 (2009)
Aggregation of Cu/Zn superoxide dismutase (SOD1) is a hallmark of a subset of familial amyotrophic lateral sclerosis (ALS) cases. The expression of wild-type SOD1 [SOD(hWT)] surprisingly exacerbates the phenotype of mutant SOD1 in vivo. Here we studi
Externí odkaz:
https://doaj.org/article/2eb8c8f628094847b138c084633e6ee4
Autor:
Luise Florin, Joanna Maus, Karsten Nalbach, Heike Huesmann, Ines F Pfalzgraf, Christian Behl, Stella Vo, Anna Stein, Anna S. Besemer, Christian M. von Hilchen, Mirjam D A Ax, Beate Silva, Fatima Boukhallouk, Andreas Kern, Christian Freese, Ingrid Koziollek-Drechsler, Albrecht M. Clement
Publikováno v:
Cellular and Molecular Life Sciences
The cellular protein homeostasis (proteostasis) network responds effectively to insults. In a functional screen in C. elegans, we recently identified the gene receptor-mediated endocytosis 8 (rme-8; human ortholog: DNAJC13) as a component of the prot
Autor:
Nadja Hellmann, Christian Behl, Martina P. Liebl, Janice Robertson, Anna S. Besemer, Heinz Decker, Albrecht M. Clement, Philbert Ip, Avijit Chakrabartty, Anna Weichert, Ingrid Koziollek-Drechsler
Publikováno v:
Neurobiology of Disease, Vol 62, Iss, Pp 479-488 (2014)
Mutations in the gene encoding Cu/Zn superoxide dismutase (SOD1) are responsible for a subset of amyotrophic lateral sclerosis cases presumably by the acquisition of as yet unknown toxic properties. Additional overexpression of wild-type SOD1 in muta
Autor:
Christian Behl, Heidrun Witan, Ali M. Kaya, Ingrid Koziollek-Drechsler, Albrecht M. Clement, Harald Neumann, Philipp Gorlovoy
Publikováno v:
Neurobiology of Disease, Vol 36, Iss 2, Pp 331-342 (2009)
Aggregation of Cu/Zn superoxide dismutase (SOD1) is a hallmark of a subset of familial amyotrophic lateral sclerosis (ALS) cases. The expression of wild-type SOD1 [SOD(hWT)] surprisingly exacerbates the phenotype of mutant SOD1 in vivo. Here we studi
Autor:
Christian Behl, Ingrid Koziollek-Drechsler, Rebecca C. Wade, Andreas Kern, Heidrun Witan, Albrecht M. Clement
Publikováno v:
Human Molecular Genetics. 17:1373-1385
Recent studies provide evidence that wild-type Cu/Zn-superoxide dismutase (SOD1(hWT)) might be an important factor in mutant SOD1-mediated amyotrophic lateral sclerosis (ALS). In order to investigate its functional role in the pathogenesis of ALS, we
Publikováno v:
Signal Transduction. 5:48-54
The nuclear receptor GCNF (NR6A1) is required for embryonic survival and development, and regulation of fertility. We used a transgenic approach to investigate its role in neural differentiation. As model we chose the embryonal carcinoma cell line PC
Autor:
Christian Behl, Vanessa Felzen, Christof Hiebel, C Brandts, Donat Kögel, S Reißig, Tobias Morawe, Ingrid Koziollek-Drechsler, Uwe Wolfrum
Publikováno v:
Cell Death & Disease
Breast cancer is a heterogeneous disease and approximately 70% of newly diagnosed breast cancers are estrogen receptor (ER) positive. Out of the two ER types, α and β, ERα is the only ER that is detectable by immunohistochemistry in breast cancer
Autor:
Albrecht M. Clement, Stefan Tenzer, Christian Behl, Martina P. Liebl, Bernd Moosmann, Romy Mittenzwei, Ali M. Kaya, Ingrid Koziollek-Drechsler, Hansjörg Schild
Publikováno v:
Free Radical Biology and Medicine. :41-54
Redox control of proteins that form disulfide bonds upon oxidative challenge is an emerging topic in the physiological and pathophysiological regulation of protein function. We have investigated the role of the neuronal calcium sensor protein visinin