Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ingrid Kolleck"'
Publikováno v:
Journal of Lipid Research, Vol 41, Iss 12, Pp 2009-2016 (2000)
The scavenger receptor class B type I (SR-BI) mediates the selective uptake of cholesterol and cholesteryl ester (CE) from high density lipoprotein (HDL) into cells. The high expression in liver and steroidogenic tissues is compatible with a role of
Externí odkaz:
https://doaj.org/article/47d291b8a81f40359043e2fba0a4f17e
Autor:
Michael Schlame, Florian Guthmann, Bernd Rüstow, Christian Schachtrup, Ingrid Kolleck, Friedrich Spener
Publikováno v:
Free Radical Biology and Medicine. 34:663-673
Reactive oxygen species play an important role in development of lung injury. Neonates exhibit a high risk of developing acute and/or chronic lung disorder, often associated with surfactant deficiency, and in parallel they show low vitamin E concentr
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 27:57-63
Alveolar type II cells accumulate vitamin E preferentially from high-density lipoproteins (HDL) and express at least three receptors that are specific for HDL. The expression of these receptors increases in response to vitamin E deficiency. Beside re
Publikováno v:
Free Radical Biology and Medicine. 30:1145-1153
Vitamin E supplementation exhibits anti-inflammatory properties. In the lung, the beneficial effects of vitamin E supplementation on inflammation and infections are well documented, but potential consequences of alimentary vitamin E deficiency to the
Publikováno v:
Lung. 178:191-200
Vitamin E is the most important lipophilic antioxidant, and beneficial effects on oxidant-caused injuries have been reported. Neonates are at high risk of oxidative injury in the lung and other organs because of a low vitamin E concentration, but the
Publikováno v:
Free Radical Biology and Medicine. 27:882-890
The alveolar surfactant is a prime target of reactive oxygen species present in air. Alveolar surfactant is supplemented with vitamin E during its assembly in type II pneumocytes. However, it is unknown which of the lipoproteins supply type II pneumo
Publikováno v:
Lipid / Fett. 98:328-331
Die oxidative Schadigung des Lungenparenchyms gilt bei vielen Lungenerkrankungen als wichtiger pathogenetischer Mechanismus in der Entwicklung obstruktiver und restriktiver Lungenfunktionsstorungen. Erster Angriffsort der mit der Atemluft aufgenommen
Publikováno v:
Cellular and molecular life sciences : CMLS. 59(11)
Glycoprotein IV (FAT/CD36) has been shown to be phosphorylated by a cAMP-dependent, platelet membrane-bound ectokinase. In this study, we demonstrate that ectophosphorylation of FAT/CD36 regulates initial palmitate uptake. This is the first time that
Publikováno v:
Biochimica et biophysica acta. 1583(1)
Pre-term neonates and neonates in general exhibit physiological vitamin E deficiency and are at increased risk for the development of acute lung diseases. Apoptosis is a major cause of acute lung damage in alveolar type II cells. In this paper, we ev
Autor:
Bernd RüSTOW, Florian Guthmann, Axel-M. Ladhoff, Ingrid Kolleck, Michael Schlame, Narendra N. Tandon
Publikováno v:
Biochemistry. 41(20)
Cholesterol is an abundant lipid of lung surfactant, where its concentration changes relative to phospholipids in response to certain physiological conditions. We investigated the effect of the cellular cholesterol content on uptake and esterificatio