Výsledky vyhledávání - "Ingrid K, Svenson"

Childhood Socioeconomic Status and Serotonin Transporter Gene Polymorphism Enhance Cardiovascular Reactivity to Mental Stress

Autor: Redford B, Williams, Douglas A, Marchuk, Ilene C, Siegler, John C, Barefoot, Michael J, Helms, Beverly H, Brummett, Richard S, Surwit, James D, Lane, Cynthia M, Kuhn, Kishore M, Gadde, Allison, Ashley-Koch, Ingrid K, Svenson, Edward C, Suarez, Saul M, Schanberg

Publikováno v: Psychosomatic Medicine. 70:32-39

To test the hypothesis that low socioeconomic status (SES) and the 5HTTLPR L allele are associated with increased cardiovascular reactivity (CVR) to stress in a larger sample and that SES and 5HTTLPR genotypes interact to enhance CVR to stress. CVR t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e711ebd3d179e763e447fd789937c8fe
https://doi.org/10.1097/psy.0b013e31815f66c3

Zobrazit plný text záznamu

Subcellular localization of spastin: implications for the pathogenesis of hereditary spastic paraplegia

Autor: Carol J. Gallione, Michael D. Ehlers, Amy Jacon, Margaret A. Pericak-Vance, Douglas A. Marchuk, April C. Horton, Ingrid K. Svenson, Mark T. Kloos

Publikováno v: Neurogenetics. 6:135-141

Hereditary spastic paraplegia (HSP) is a group of clinically and genetically heterogeneous diseases characterized by neuronal degeneration that is maximal at the distal ends of the longest axons of the central nervous system. The most common cause of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f739a3ce1f9c08cfca7582c806df3b
https://doi.org/10.1007/s10048-005-0219-2

Zobrazit plný text záznamu

Autor: Greg L. Clary, Kishore M. Gadde, Ingrid K. Svenson, Ilene C. Siegler, Katherine P. Grichnik, Douglas A. Marchuk, Mark Stafford-Smith, Michael J. Helms, Redford B. Williams, John C. Barefoot, Saul M. Schanberg, Cynthia M. Kuhn, Edward C. Suarez, James G. Lewis

Publikováno v: Neuropsychopharmacology. 28:533-541

Central nervous system (CNS) serotonergic function affects a wide range of biological and behavioral functions affecting health and disease. Our objective in this study was to determine whether functional polymorphisms of the genes that encode for th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645e719b4cf1dc38d7b692a74df177ee
https://doi.org/10.1038/sj.npp.1300054

Zobrazit plný text záznamu

Allelic Differences in the Serotonin Transporter-Linked Polymorphic Region in Geriatric Depression

Autor: Ilene C. Siegler, Ingrid K. Svenson, Douglas A. Marchuk, Judith C. Hays, David C. Steffens, Robert M. Levy, Elizabeth P. Flint, K. Ranga Rama Krishnan

Publikováno v: The American Journal of Geriatric Psychiatry. 10:185-191

Previous studies have examined the role of genetic variations in the serotonin transporter-linked polymorphic region (5HTTLPR) in affective disorders. The authors studied 182 older depressed subjects and 107 elderly control subjects and obtained DNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90256034a6e91a451639cb69474e3d15
https://doi.org/10.1097/00019442-200203000-00009

Zobrazit plný text záznamu

Identification and Expression Analysis of Spastin Gene Mutations in Hereditary Spastic Paraplegia

Autor: P. Craig Gaskell, W. J.Ken Cumming, Ingrid K. Svenson, Margaret A. Pericak-Vance, Travis J. Riney, Martha Nance, Edward L. Hogan, Rose-Mary Boustany, Douglas A. Marchuk, Helen Kingston, Allison E. Ashley-Koch, Jeffery M. Vance

Publikováno v: The American Journal of Human Genetics. 68:1077-1085

Pure hereditary spastic paraplegia (SPG) type 4 is the most common form of autosomal dominant hereditary SPG, a neurodegenerative disease characterized primarily by hyperreflexia and progressive spasticity of the lower limbs. It is caused by mutation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1422b392cf1c94e67cec72e256d910e
https://doi.org/10.1086/320111

Zobrazit plný text záznamu

Central Nervous System Serotonin Function and Cardiovascular Responses to Stress

Autor: Douglas A. Marchuk, Katherine P. Grichnik, Greg L. Clary, Redford B. Williams, John C. Barefoot, Cynthia M. Kuhn, Mark Stafford-Smith, Ilene C. Siegler, Ingrid K. Svenson, Saul M. Schanberg, Edward C. Suarez, James G. Lewis, Kishore M. Gadde, Michael J. Helms

Publikováno v: Psychosomatic Medicine. 63:300-305

Objective The objective of this study was to evaluate the impact of indices of central nervous system (CNS) serotonin function on cardiovascular reactivity to mental stress. Methods Lumbar puncture was performed on 54 healthy volunteers to obtain cer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::367cd3350de0b1d5e86a39bcf690ab64
https://doi.org/10.1097/00006842-200103000-00016

Zobrazit plný text záznamu

Intragenic modifiers of hereditary spastic paraplegia due to spastin gene mutations

Autor: James Y. Garbern, Douglas A. Marchuk, Margaret A. Pericak-Vance, Ingrid K. Svenson, P. Craig Gaskell, Martha Nance, Shin-ichi Hisanaga, Allison E. Ashley-Koch, Mark T. Kloos

Publikováno v: Neurogenetics. 5(3)

Hereditary spastic paraplegia (HSP) is a genetically heterogeneous neurodegenerative disease characterized by wide variability in phenotypic expression, both within and among families. The most-common cause of autosomal dominant HSP is mutation of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4551dd62f179ae37d5d0d499d67a1699
https://pubmed.ncbi.nlm.nih.gov/15248095

Zobrazit plný text záznamu

Associations among the NEO Personality Inventory, Revised and the serotonin transporter gene-linked polymorphic region in elders: effects of depression and gender

Autor: Ilene C. Siegler, David C. Steffens, Beverly H. Brummett, Ingrid K. Svenson, Douglas R. McQuoid, Douglas A. Marchuk

Publikováno v: Psychiatric genetics. 13(1)

OBJECTIVE: The short variant of the serotonin transporter gene-linked functional polymorphic region (5-HTTLPR) has been associated with personality traits related to anxiety, hostility, and depression. We attempted to replicate findings suggesting a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea28df66c33d97bd0590f2df37648293
https://pubmed.ncbi.nlm.nih.gov/12605095

Zobrazit plný text záznamu

Fine mapping and genetic heterogeneity in the pure form of autosomal dominant familial spastic paraplegia

Autor: Jeffery M. Vance, William K. Scott, Allison E. Ashley-Koch, Margaret A. Pericak-Vance, Ingrid K. Svenson, Sandra G. West, Chantelle M. Wolpert, Douglas A. Marchuk, Martha Nance, Erin Bonner, Richard W. Tim, Rodney Jones, Rose-Mary Boustany, Carolyn Farrell, P. Craig Gaskell

Publikováno v: Neurogenetics. 3(2)

We evaluated seven families segregating pure, autosomal dominant familial spastic paraplegia (SPG) for linkage to four recently identified SPG loci on chromosomes 2q (1), 8q (2), 12q (3), and 19q (4). These families were previously shown to be unlink

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e883d4f2ed23cb1d6baf62ed1ef73e93
https://pubmed.ncbi.nlm.nih.gov/11354831

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání