Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ingrid J. de Vries-van Leeuwen"'
Autor:
Sascha Fuchs, Matthew F. Burton, Christian Ottmann, Lidia Nieto, Stijn M. Agten, Andrea Schmidt, Trang Thi Phuong Phan, Luc Brunsveld, Ingrid J. de Vries-van Leeuwen, Monireh Goodarzifard, Lech-Gustav Milroy, Hoang Duc Nguyen, Rolf Rose
Publikováno v:
Journal of the American Chemical Society, 135(11), 4364-4371. American Chemical Society
Nuclear receptor binding to coactivator proteins is an obligate first step in the regulation of gene transcription. Nuclear receptors preferentially bind to an LXXLL peptide motif which is highly conserved throughout the 300 or so natural coactivator
Autor:
Sjors Kas, Chantal Kortekaas-Thijssen, Jean A. Nzigou Mandouckou, Albertus H. de Boer, Antonio Evidente, Ingrid J. de Vries-van Leeuwen
Publikováno v:
Cancer Letters, 198-206. Elsevier Ireland Ltd
STARTPAGE=198;ENDPAGE=206;ISSN=0304-3835;TITLE=Cancer Letters
de Vries-van Leeuwen, I J, Kortekaas-Thijssen, C, Nzigou Mandouckou, J A, Kas, S, Evidente, A & de Boer, A H 2010, ' Fusicoccin-A selectively induces apoptosis in tumor cells after interferon-alpha priming. ', Cancer Letters, pp. 198-206 . https://doi.org/10.1016/j.canlet.2010.01.009
STARTPAGE=198;ENDPAGE=206;ISSN=0304-3835;TITLE=Cancer Letters
de Vries-van Leeuwen, I J, Kortekaas-Thijssen, C, Nzigou Mandouckou, J A, Kas, S, Evidente, A & de Boer, A H 2010, ' Fusicoccin-A selectively induces apoptosis in tumor cells after interferon-alpha priming. ', Cancer Letters, pp. 198-206 . https://doi.org/10.1016/j.canlet.2010.01.009
Active small molecules have a high potential for the development into new anti-cancer drugs. Here we analysed the effect of the natural occurring fusicoccanes, Fusicoccin-A (FC), Ophiobolin-A (OPH-A) and Ophiobolin-I (OPH-I) on various tumor cell lin
Autor:
Tom F. A. de Greef, Albertus H. de Boer, Koen D. Flach, Christian Haase, David Bier, Christian Ottmann, Connie R. Jimenez, Luc Brunsveld, Zeliha Yalcin, Ingrid J. de Vries-van Leeuwen, Sander R. Piersma, Daniel Da Costa Pereira, Rob Michalides, Wilbert Zwart, K. Anton Feenstra
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 110(22), 8894-9. National Acad Sciences
De Vries-van Leeuwen, I J, da Costa Pereira, D, Flach, K D, Piersma, S R, Haase, C, Bier, D, Yalcin, Z, Michalides, R, Feenstra, K A, Jiménez, C R, de Greef, T F A, Brunsveld, L, Ottmann, C, Zwart, W & de Boer, A H 2013, ' Interaction of 14-3-3 proteins with the Estrogen Receptor Alpha F domain provides a drug target interface ', Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 22, pp. 8894-9 . https://doi.org/10.1073/pnas.1220809110
Proceedings of the National Academy of Sciences of the United States of America (PNAS), 110(22), 8894-8899. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 110(22), 8894-8899. National Academy of Sciences
van Leeuwen, I J, da Costa Pereira, D, Flach, K D, Piersma, S R, Haase, C, Bier, D, Yalcin, Z, Michalides, R, Feenstra, K A, Jimenez, C R, de Greef, T F A, Brunsveld, L, Ottmann, C, Zwart, W & de Boer, A H 2013, ' Interaction of 14-3-3 proteins with the Estrogen Receptor Alpha F domain provides a drug target interface ', Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 22, pp. 8894-8899 . https://doi.org/10.1073/pnas.1220809110
De Vries-van Leeuwen, I J, da Costa Pereira, D, Flach, K D, Piersma, S R, Haase, C, Bier, D, Yalcin, Z, Michalides, R, Feenstra, K A, Jiménez, C R, de Greef, T F A, Brunsveld, L, Ottmann, C, Zwart, W & de Boer, A H 2013, ' Interaction of 14-3-3 proteins with the Estrogen Receptor Alpha F domain provides a drug target interface ', Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 22, pp. 8894-9 . https://doi.org/10.1073/pnas.1220809110
Proceedings of the National Academy of Sciences of the United States of America (PNAS), 110(22), 8894-8899. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America, 110(22), 8894-8899. National Academy of Sciences
van Leeuwen, I J, da Costa Pereira, D, Flach, K D, Piersma, S R, Haase, C, Bier, D, Yalcin, Z, Michalides, R, Feenstra, K A, Jimenez, C R, de Greef, T F A, Brunsveld, L, Ottmann, C, Zwart, W & de Boer, A H 2013, ' Interaction of 14-3-3 proteins with the Estrogen Receptor Alpha F domain provides a drug target interface ', Proceedings of the National Academy of Sciences of the United States of America, vol. 110, no. 22, pp. 8894-8899 . https://doi.org/10.1073/pnas.1220809110
Estrogen receptor alpha (ERα) is involved in numerous physiological and pathological processes, including breast cancer. Breast cancer therapy is therefore currently directed at inhibiting the transcriptional potency of ERα, either by blocking estr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04c11ff8b1370c1f32f07dc69da26d4
https://research.vu.nl/en/publications/d9b9ce38-257b-45a9-be5a-294acfa171af
https://research.vu.nl/en/publications/d9b9ce38-257b-45a9-be5a-294acfa171af
Autor:
Denis A. Vysotskii, Ingrid J. de Vries-van Leeuwen, Albertus H. de Boer, Alexei V. Babakov, Erik Souer
Publikováno v:
Plant Signaling & Behavior
Plant Signaling & Behavior, 8(1). Landes Bioscience
Vysotskii, D A, de Vries-van Leeuwen, I J, Souer, E, Babakov, A V & de Boer, A H 2012, ' ABF transcription factors of Thellungiella salsuginea: structure, expression profiles and interaction with 14-3-3 regulatory proteins ', Plant Signaling & Behavior, vol. 8, no. 1 . https://doi.org/10.4161/psb.22672
Plant Signaling & Behavior, 8(1). Landes Bioscience
Vysotskii, D A, de Vries-van Leeuwen, I J, Souer, E, Babakov, A V & de Boer, A H 2012, ' ABF transcription factors of Thellungiella salsuginea: structure, expression profiles and interaction with 14-3-3 regulatory proteins ', Plant Signaling & Behavior, vol. 8, no. 1 . https://doi.org/10.4161/psb.22672
ABF transcription factors are the key regulators of ABA signaling. Using RACE-PCR, we identified and sequenced the coding regions of four genes that encode ABF transcription factors in the extremophile plant Thellungiella salsuginea, a close relative
Publikováno v:
de Boer, A H & de Vries-van Leeuwen, I J 2012, ' Fusicoccanes: diterpenes with surprising biological functions ', Trends in Plant Science, vol. 17, pp. 360-368 . https://doi.org/10.1016/j.tplants.2012.02.007
Trends in Plant Science, 17, 360-368. Elsevier Limited
Trends in Plant Science, 17, 360-368. Elsevier Limited
Fusicoccin is the best-studied member of a class of diterpenes sharing a 5-8-5 ring structure, called fusicoccanes. Fusicoccin was and still is a ‘tool in plant physiology’, targeting the main engine of plasma membrane transport, the P-type H + -