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pro vyhledávání: '"Ingrid J. Liepe"'
Autor:
Paul J. White, Stephanie R. Edmondson, Christopher J. Wraight, Sandra C. McKean, Daryl J. Venables, Ingrid J. Liepe, George A. Werther, Rhys Fogarty
Publikováno v:
Nature Biotechnology. 18:521-526
Epidermal hyperplasia is a key feature of the common skin disorder psoriasis. Stimulation of epidermal keratinocytes by insulin-like growth factor I (IGF-I) is essential for cell division, and increased sensitivity to IGF-I may occur in psoriasis. We
Autor:
Paul J. White, Christopher J. Wraight, Ingrid J. Liepe, Rhys Fogarty, George A. Werther, Peter M Delaney
Publikováno v:
Journal of Investigative Dermatology. 112(6):887-892
Anti-sense oligonucleotide uptake by keratinocytes in human skin grafts on athymic mice was examined using live confocal microscopy. Fluorescein isothiocyanate-labeled 15-mer C-5 propyne modified phosphorothioate anti-sense oligonucleotide (10-50 mic
Publikováno v:
The Journal of investigative dermatology. 111(2)
Insulin-like growth factor-I (IGF-I) stimulation of basal keratinocytes is an essential component of normal epidermal homeostasis. In addition to the IGF receptor, basal keratinocytes synthesize insulin-like growth factor binding protein-3 (IGFBP-3).