Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ingrid J, Van Dillen"'
Autor:
Willem Vaalburg, Steven de Jong, Marc Mesnil, Geke A. P. Hospers, Jadranka Loncarek, Ingrid J van Dillen, Erik F. J. de Vries, Coby Meijer, Wim J. Sluiter, Nanno Mulder
Publikováno v:
Scopus-Elsevier
Oncology research, 15(3), 151-159
Oncology research, 15(3), 151-159
The p53 protein is mutated in 50% of all human tumors and plays a key role in apoptosis, cell cycle, and the expression of several genes. We investigated if p53 mutations influence the herpes simplex virus thymidine kinase (HSV-tk)/ganciclovir (GCV)-
Autor:
Erik F. J. de Vries, Nanno Mulder, Ingrid J van Dillen, Willem Vaalburg, Geke A. P. Hospers, Antoon T. M. Willemsen, Aren van Waarde
Publikováno v:
Nuclear Medicine and Biology, 30(6), 651-660. ELSEVIER SCIENCE INC
In rats, the relationship between [F-18]FHPG accumulation and HSVtk expression was studied with PET and autoradiography. [F-18]FHPG distribution closely corresponded with HSVtk immunohistochemical staining. ROI analysis of tracer uptake 2 hours p.i.
Autor:
Ingrid J, Van Dillen, Nanno H, Mulder, Wim J, Sluiter, Coby, Meijer, Steven, De Jong, Jadranka, Loncarek, Marc, Mesnil, Erik F J, De Vries, Willem, Vaalburg, Geke A P, Hospers
Publikováno v:
Anticancer research. 25(1A)
This paper focuses on the influence of chemoresistance on the herpes simplex virus (HSV-tk)/ganciclovir (GCV)-induced bystander effect (BE), as studied in a human small cell lung cancer (SCLC) cell line (GLC4) and its sublines with in vitro acquired
Publikováno v:
Curr.Gene Ther., 2(3), 307-22
Despite the development of new therapeutic strategies, cancer remains incurable in most patients with advanced disease. A recent potential improvement in therapeutic strategies is the concept of suicide gene therapy. After transfection with a suicide