Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Ingrid H.C.H.M. Philippens"'
Autor:
Ingrid H.C.H.M. Philippens
Publikováno v:
Neuropraxis. 24:28-35
In de substantia nigra bevinden zich dopamine-producerende zenuwcellen die de motorcoordinatie regelen. Bij de ziekte van Parkinson sterven deze cellen af. Het feit dat de eerste parkinsonsymptomen pas optreden zodra er meer dan 60 % van die specifie
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, 11(1):11751. Nature Publishing Group
Scientific Reports
Scientific Reports, 11(1):11751. Nature Publishing Group
Scientific Reports
Deep brain stimulation (DBS) of the nucleus basalis of Meynert (NBM) has been clinically investigated in Alzheimer’s disease (AD) and Lewy body dementia (LBD). However, the clinical effects are highly variable, which questions the suggested basic p
Publikováno v:
European Neuropsychopharmacology, 50, 1-11. Elsevier
European Neuropsychopharmacology, 50, 1-11. ELSEVIER
European Neuropsychopharmacology, 50, 1-11. ELSEVIER
Emotionally arousing experiences are retained very well as seen in posttraumatic stress disorder (PTSD). Various lines of evidence indicate that reactivation of these memories renders them labile which offers a potential time-window for intervention.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d9d6cb26774ba7afd53dfa6f64242fd
https://dare.uva.nl/personal/pure/en/publications/ketamine-treatment-upon-memory-retrieval-reduces-fear-memory-in-marmoset-monkeys(be646865-83e8-4938-9235-b7f7d245017e).html
https://dare.uva.nl/personal/pure/en/publications/ketamine-treatment-upon-memory-retrieval-reduces-fear-memory-in-marmoset-monkeys(be646865-83e8-4938-9235-b7f7d245017e).html
Autor:
Eva Roos, Babs E. Verstrepen, Ernst J. Verschoor, Marianna Bugiani, Lioe-Fee de Geus-Oei, Jan A.M. Langermans, Jacqueline Wubben, Ronald E. Bontrop, Willy M. J. M. Bogers, Diana Lozovagia, Zahra Fagrouch, Bernadette Schurink, Amber Q. Mayenburg, Nikki van Driel, Marieke A. Stammes, Ingrid H.C.H.M. Philippens, Jinte Middeldorp, Kinga P. Böszörményi
SARS-CoV-2 may cause acute respiratory disease, but the infection can also initiate neurological symptoms. Here we show that SARS-CoV-2 infection causes brain inflammation in the macaque model. An increased metabolic activity in the pituitary gland o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a26d4958b42abf56a35b0790ad5ab6f
https://doi.org/10.1101/2021.02.23.432474
https://doi.org/10.1101/2021.02.23.432474
Autor:
Ingrid H.C.H.M. Philippens
Publikováno v:
Drug Discovery Today: Disease Models. :53-61
The increasing prevalence of age-related neurodegenerative diseases is a growing concern for the ageing societies. Parkinson’s disease is a major progressive motor disorder of the brain caused by specific degeneration of the dopamine-producing neur
Autor:
Ingrid H.C.H.M. Philippens, Paul R. Ormel, Guus Baarends, Magnus Doverskog, Maja Johansson, E. J. Remarque
Publikováno v:
Journal of Alzheimer's Disease
Background The immune system is increasingly mentioned as a potential target for Alzheimer's disease (AD) treatment. Objective In the present pilot study, the effect of (neuro)inflammation on amyloidopathy was investigated in the marmoset monkey, whi
Autor:
Jan A.M. Langermans, Sam O. Hofman, Ingrid H.C.H.M. Philippens, Sigrid K. Franke, Jacqueline Wubben
Publikováno v:
Scientific Reports, 9:880, 1-9. Nature Publishing Group
Scientific Reports
Scientific Reports, 9(1). NLM (Medline)
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Philippens, I H C H M, Wubben, J A, Franke, S K, Hofman, S & Langermans, J A M 2019, ' Involvement of the Red Nucleus in the Compensation of Parkinsonism may Explain why Primates can develop Stable Parkinson’s Disease ', Scientific Reports, vol. 9, 880, pp. 1-9 . https://doi.org/10.1038/s41598-018-37381-1
Scientific Reports
Scientific Reports, 9(1). NLM (Medline)
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Philippens, I H C H M, Wubben, J A, Franke, S K, Hofman, S & Langermans, J A M 2019, ' Involvement of the Red Nucleus in the Compensation of Parkinsonism may Explain why Primates can develop Stable Parkinson’s Disease ', Scientific Reports, vol. 9, 880, pp. 1-9 . https://doi.org/10.1038/s41598-018-37381-1
Neurological compensatory mechanisms help our brain to adjust to neurodegeneration as in Parkinson’s disease. It is suggested that the compensation of the damaged striato-thalamo-cortical circuit is focused on the intact thalamo-rubro-cerebellar pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae090b2248635460ea4d302005f1399c
https://research.vu.nl/en/publications/1ece4d82-5f1b-4609-8fd6-35bfdddf40f8
https://research.vu.nl/en/publications/1ece4d82-5f1b-4609-8fd6-35bfdddf40f8
Autor:
David H. Abbott, Lyndsey Ace, Arrilton Araujo, Hayley Ash, Bert A. 't Hart, David G. Baker, Jaco Bakker, Victoria K. Baxter, Martina Bleyer, Monika Burns, Christophe Casteleyn, Maria de Fátima Arruda, Jordon Dunham, Steven J. Eliades, Jeffrey Everitt, James G. Fox, Jeffrey A. French, Makoto Fukushima, Caroline M. Garrett, Anna Goodroe, Jennifer Haupt, Noritaka Ichinohe, Yolanda S. Kap, Sven Korte, Liz Koutsos, Joshua A. Kramer, Robin Kramer, Marissa Kraynak, Robert E. Lanford, Donna Layne-Colon, David A. Leopold, Jon E. Levine, Keith G. Mansfield, Robert P. Marini, Daniel Marques de Almeida Pessoa, Kerstin Mätz-Rensing, Kelly A. Metcalf Pate, Andrew D. Miller, Jude F. Mitchell, Hideyuki Okano, Jean L. Patterson, Ingrid H.C.H.M. Philippens, Michael L. Power, Corinna N. Ross, Erika Sasaki, Nancy Schultz-Darken, Gillian C. Shaw, Suzette D. Tardif, Joji Tsunada, Eric J. Vallender, Lynn Wachtman, Maria Emilia Yamamoto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::701730782407740664a7805a754754b4
https://doi.org/10.1016/b978-0-12-811829-0.01002-5
https://doi.org/10.1016/b978-0-12-811829-0.01002-5
Autor:
Ingrid H.C.H.M. Philippens
The increasing prevalence of age-related neurodegenerative diseases, such as Parkinson's disease, is a growing concern for aging Western societies. As there is no cure for this progressive disease, we still have to rely on symptom control treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::841d091b8cdc02e7028bdac09cd8532d
https://doi.org/10.1016/b978-0-12-811829-0.00023-6
https://doi.org/10.1016/b978-0-12-811829-0.00023-6
Autor:
Piero Carninci, Imad Abugessaisa, Ingrid H.C.H.M. Philippens, Timo Lassmann, Luba M. Pardo, Marina Lizio, Jayson Harshbarger, Akira Hasegawa, Mizuho Sakai, Masayoshi Itoh, Margherita Francescatto, Takeya Kasukawa, Peter Heutink, Patrizia Rizzu, Alistair R. R. Forrest, Shoko Watanabe, Yoshihide Hayashizaki, Jessica Severin, Ronald E. Bontrop, Hideya Kawaji
Publikováno v:
Scientific Data
Scientific data 5(1), 2 (2018). doi:10.1038/s41597-018-0003-4
Scientific Data, Vol 5, Iss 1, Pp 1-1 (2018)
Scientific data 5(1), 2 (2018). doi:10.1038/s41597-018-0003-4
Scientific Data, Vol 5, Iss 1, Pp 1-1 (2018)
Rhesus macaque was the second non-human primate whose genome has been fully sequenced and is one of the most used model organisms to study human biology and disease, thanks to the close evolutionary relationship between the two species. But compared