Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Ingrid Catz"'
Autor:
Glen B. Baker, Kenneth G. Warren, Christopher Power, Brian D. Sykes, Stacey N. Reinke, David Broadhurst, Ingrid Catz
Publikováno v:
Multiple Sclerosis Journal. 20:1396-1400
Metabolomics enables the provision of sensitive bio-markers of disease. We performed 800 MHz 1H-nuclear magnetic resonance (NMR) spectroscopic analyses of cerebrospinal fluid (CSF) specimens to identify biomarkers of multiple sclerosis (MS), yielding
Publikováno v:
European Journal of Neurology. 13:887-895
MBP8298 is a synthetic peptide with a sequence corresponding to amino acid residues 82-98 of human myelin basic protein (DENPVVHFFKNIVTPRT). It represents the immunodominant target for both B cells and T cells in multiple sclerosis (MS) patients with
Autor:
Jennifer L. Kanter, Raymond A. Sobel, Lawrence Steinman, William H. Robinson, Ingrid Catz, Sirisha Narayana, Peggy P. Ho, Kenneth G. Warren
Publikováno v:
Nature Medicine. 12:138-143
Recent studies suggest that increased T-cell and autoantibody reactivity to lipids may be present in the autoimmune demyelinating disease multiple sclerosis. To perform large-scale multiplex analysis of antibody responses to lipids in multiple sclero
Autor:
K.G. Warren, Ingrid Catz
Publikováno v:
Multiple Sclerosis Journal. 6:300-311
Multiple sclerosis [MS], a demyelinating disease of the central nervous system associated with inflammation and gliosis, may be an autoimmune disease with T lymphocytes and autoantibodies to myelin protein(s). This study deals exclusively with B cell
Autor:
Stefan Hausmann, Kai W. Wucherpfennig, Kenneth G. Warren, Lawrence Steinman, Jack L. Strominger, Ingrid Catz
Publikováno v:
Journal of Clinical Investigation. 100:1114-1122
Myelin basic protein (MBP) may be an important autoantigen in multiple sclerosis (MS), with the MBP(82-100) region being immunodominant for T cells and autoantibodies. The structural requirements for autoantibody recognition were compared to those pr
Autor:
Gregg Blevins, Jian-Qiang Lu, Andrew J. Walsh, R. Marc Lebel, Ingrid Catz, Alan H. Wilman, Kenneth G. Warren, Edward S. Johnson, Derek Emery, Amir Eissa, Lothar Resch
Publikováno v:
Radiology. 267(2)
To investigate the relationship between iron staining and magnetic resonance (MR) imaging measurements in postmortem subjects with multiple sclerosis (MS).Institutional ethical approval was obtained, and informed consent was obtained from the subject
Autor:
Kenneth G. Warren, Ingrid Catz
Publikováno v:
Journal of the Neurological Sciences. 115:169-176
Previous research has demonstrated that free (F) and bound (B) anti-myelin basic protein (anti-MBP) can be detected in the cerebrospinal fluid (CSF) of patients with active multiple sclerosis (MS). The purpose of this report was to determine whether
Publikováno v:
Journal of the Neurological Sciences. 109:88-95
Elevated titers of anti-myelin basic protein (anti-MBP) are highly associated with acute idiopathic unilateral optic neuritis as well as acute relapses of multiple sclerosis (MS). During acute phases of optic neuritis, free/bound antibody ratios are
Autor:
Ingrid Catz, Amir Eissa, R. Marc Lebel, Kenneth G. Warren, Derek Emery, Alan H. Wilman, Anna E. Zavodni, Jeff R. Korzan
Publikováno v:
Journal of magnetic resonance imaging : JMRI. 30(4)
Purpose To demonstrate 4.7 Tesla (T) imaging methods for visualizing lesions in multiple sclerosis in the human brain using phase susceptibility-weighting and T2 weighting. Materials and Methods Seven patients with relapsing-remitting multiple sclero
Autor:
Ingrid Catz, Kenneth G. Warren
Publikováno v:
Journal of the Neurological Sciences. 96:19-27
Immunoglobulin G (IgG) was purified by affinity chromatography from the CSF of multiple sclerosis (MS) patients and controls. In MS patients, the IgG fraction contains anti-myelin basic protein (anti-MBP), anti-MBP neutralizing antibody and an antibo