Strategy inference during learning via cognitive activity-based credit assignment models

Autor: Ashwin James, Patricia Reynaud-Bouret, Giulia Mezzadri, Francesca Sargolini, Ingrid Bethus, Alexandre Muzy

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)

Abstract We develop a method for selecting meaningful learning strategies based solely on the behavioral data of a single individual in a learning experiment. We use simple Activity-Credit Assignment algorithms to model the different strategies and c

Externí odkaz: https://doaj.org/article/d9a707e3465548d29d0d28ab2b52d824

A two-hit story: Seizures and genetic mutation interaction sets phenotype severity in SCN1A epilepsies

Autor: Ana Rita Salgueiro-Pereira, Fabrice Duprat, Paula A. Pousinha, Alexandre Loucif, Vincent Douchamps, Cristina Regondi, Marion Ayrault, Martine Eugie, Marion I. Stunault, Andrew Escayg, Romain Goutagny, Vadym Gnatkovsky, Carolina Frassoni, Hélène Marie, Ingrid Bethus, Massimo Mantegazza

Publikováno v: Neurobiology of Disease, Vol 125, Iss , Pp 31-44 (2019)

SCN1A (NaV1.1 sodium channel) mutations cause Dravet syndrome (DS) and GEFS+ (which is in general milder), and are risk factors in other epilepsies. Phenotypic variability limits precision medicine in epilepsy, and it is important to identify factors

Externí odkaz: https://doaj.org/article/8709f3f818c945c2a74432572ef04cdb

The Amyloid Precursor Protein C-Terminal Domain Alters CA1 Neuron Firing, Modifying Hippocampus Oscillations and Impairing Spatial Memory Encoding

Autor: Paula A. Pousinha, Xavier Mouska, Daniela Bianchi, Mariana Temido-Ferreira, Joana Rajão-Saraiva, Rui Gomes, Sebastian P. Fernandez, Ana Rita Salgueiro-Pereira, Carine Gandin, Elisabeth F. Raymond, Jacques Barik, Romain Goutagny, Ingrid Bethus, Luisa V. Lopes, Michele Migliore, Hélène Marie

Publikováno v: Cell Reports, Vol 29, Iss 2, Pp 317-331.e5 (2019)

Summary: There is a growing consensus that Alzheimer's disease (AD) involves failure of the homeostatic machinery, which underlies the firing stability of neural circuits. What are the culprits leading to neuron firing instability? The amyloid precur

Externí odkaz: https://doaj.org/article/90855fdcacba470a93f8234bea3604cb

Episodic Memory formation: A review of complex Hippocampus input pathways

Autor: Krubeal Danieli, Alice Guyon, Ingrid Bethus

Publikováno v: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 126:110757

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e7a1cad64f718a50dbc4905c5da10075
https://doi.org/10.1016/j.pnpbp.2023.110757

A two-hit story: Seizures and genetic mutation interaction sets phenotype severity in SCN1A epilepsies

Autor: Romain Goutagny, Hélène Marie, Ingrid Bethus, Martine Eugie, Andrew Escayg, Ana Rita Salgueiro-Pereira, Paula A. Pousinha, Marion I. Stunault, Vincent Douchamps, Alexandre J.C. Loucif, Vadym Gnatkovsky, Marion Ayrault, Fabrice Duprat, Massimo Mantegazza, Carolina Frassoni, Cristina Regondi

Publikováno v: Neurobiology of Disease
Neurobiology of Disease, Elsevier, 2019, 125, pp.31-44. ⟨10.1016/j.nbd.2019.01.006⟩
Neurobiology of Disease, Vol 125, Iss, Pp 31-44 (2019)
Neurobiology of Disease, 2019, 125, pp.31-44. ⟨10.1016/j.nbd.2019.01.006⟩

International audience; SCN1A (NaV1.1 sodium channel) mutations cause Dravet syndrome (DS) and GEFS+ (which is in general milder), and are risk factors in other epilepsies. Phenotypic variability limits precision medicine in epilepsy, and it is impor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3146c1da3b3f4b3000af24b4e3fcb4c7
https://hal.archives-ouvertes.fr/hal-02166065