Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ingrid B.J. Joseph"'
Autor:
David R. Stover, Dennis Benjamin, Pia Challita-Eid, Ingrid B.J. Joseph, Fernando Doñate, Daniel S. Pereira, Ying Li, Jeffrey Coleman, Steven Duniho, Ruth Moser, Faisal Malik, Claudia Guevara, Hector Aviña, Rossana Nadell, Jimmy Ou, Monica Leavitt, Alla Verlinsky, Linnette Capo, Zili An, Karen Morrison, Kendall Morrison, Arthur Raitano, Michael Mattie
Here, we report the development of an antibody–drug conjugate, ASG-5ME, which targets the solute carrier receptor SLC44A4. SLC44A4 is a member of a family of putative choline transporters that we show to be markedly upregulated in a variety of epit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::510fb86e62a3f121e464a29893f6e996
https://doi.org/10.1158/1535-7163.c.6538426.v1
https://doi.org/10.1158/1535-7163.c.6538426.v1
Autor:
David R. Stover, John E. Dick, Thomas J. Kipps, Ingrid B.J. Joseph, Fernando Doñate, Pia M. Challita-Eid, Kendall Morrison, Zili An, Michael Y. Choi, Faisal Malik, Sung-Ju Moon, Peng Yang, Joseph D. Abad, Sher Karki, Hector Aviña, Ssucheng J. Hsu, Alla Verlinsky, Nathan Mbong, Liqing Jin, Claudia I. Guevara, Daniel S. Pereira
CD37 is a tetraspanin expressed on malignant B cells. Recently, CD37 has gained interest as a therapeutic target. We developed AGS67E, an antibody–drug conjugate that targets CD37 for the potential treatment of B/T-cell malignancies. It is a fully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1527556d255efa3b01de73ceaefa5731
https://doi.org/10.1158/1535-7163.c.6536874.v1
https://doi.org/10.1158/1535-7163.c.6536874.v1
Autor:
David R. Stover, John E. Dick, Thomas J. Kipps, Ingrid B.J. Joseph, Fernando Doñate, Pia M. Challita-Eid, Kendall Morrison, Zili An, Michael Y. Choi, Faisal Malik, Sung-Ju Moon, Peng Yang, Joseph D. Abad, Sher Karki, Hector Aviña, Ssucheng J. Hsu, Alla Verlinsky, Nathan Mbong, Liqing Jin, Claudia I. Guevara, Daniel S. Pereira
Figure S1: AGS67E Binds To B-Cells With High Affinity and Induces Cytotoxicity. Figure S2: AGS67E and AGS67C Internalize Into B Cell Lymphma Cells. Figure S3: AGS67E But Not AGS67C Exhibits Anti-Tumor Activity In MOLM-13 Xenografts. Figure S4: AGS67C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a083c06965c0eadcd1fd9019b5efb71f
https://doi.org/10.1158/1535-7163.22501707
https://doi.org/10.1158/1535-7163.22501707
Autor:
David R. Stover, Dennis Benjamin, Pia Challita-Eid, Ingrid B.J. Joseph, Fernando Doñate, Daniel S. Pereira, Ying Li, Jeffrey Coleman, Steven Duniho, Ruth Moser, Faisal Malik, Claudia Guevara, Hector Aviña, Rossana Nadell, Jimmy Ou, Monica Leavitt, Alla Verlinsky, Linnette Capo, Zili An, Karen Morrison, Kendall Morrison, Arthur Raitano, Michael Mattie
Figure S1. Proteolytic release of MMAE from ASG-5ME; Figure S2. SLC44A4 RNA expression in normal and tumor specimens from combined Oncomine data sets; Figure S3: Expression of SLC44A4 in OVCAR-5 cells determined by FACS.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed5c9b6bfa05d8cb976b95011b8f210
https://doi.org/10.1158/1535-7163.22506523
https://doi.org/10.1158/1535-7163.22506523
Autor:
David R. Stover, Karen Morrison, Daniel S. Pereira, Ingrid B.J. Joseph, Fernando Doñate, Hector Aviña, Alla Verlinsky, Linnette Capo, Josh T. Snyder, Dawn Ratay Lortie, Wendy Liu, Joseph D. Abad, Peng Yang, Zili An, Arthur Raitano, Pia M. Challita-Eid, Kendall Morrison
SLITRK6 is a member of the SLITRK family of neuronal transmembrane proteins that was discovered as a bladder tumor antigen using suppressive subtractive hybridization. Extensive immunohistochemistry showed SLITRK6 to be expressed in multiple epitheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57c7e29afe45a3470c1c88725becfe7e
https://doi.org/10.1158/1535-7163.c.6537600
https://doi.org/10.1158/1535-7163.c.6537600
Autor:
David R. Stover, Karen Morrison, Daniel S. Pereira, Ingrid B.J. Joseph, Fernando Doñate, Hector Aviña, Alla Verlinsky, Linnette Capo, Josh T. Snyder, Dawn Ratay Lortie, Wendy Liu, Joseph D. Abad, Peng Yang, Zili An, Arthur Raitano, Pia M. Challita-Eid, Kendall Morrison
Details on how the IHC reagent reported in this paper was generated and validated.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a45130ccf051fe615d169867a44dd0d
https://doi.org/10.1158/1535-7163.22504038
https://doi.org/10.1158/1535-7163.22504038
Autor:
David R. Stover, Pia M. Challita-Eid, Daniel S. Pereira, Ingrid B.J. Joseph, John Atkinson, Daulet Satpayev, Wendy Liu, Rossana Nadell, Faisal Malik, Yuriy Shostak, Ryuichi Moriya, Jimmy Ou, Peng Yang, Karen Morrison, Sher Karki, Hector Aviña, Linnette Capo, Zili An, Kendall Morrison, Arthur Raitano, Fernando Doñate
Supplemental Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::071a72a470db5adede0722ce6e0e19a7
https://doi.org/10.1158/1078-0432.22460346
https://doi.org/10.1158/1078-0432.22460346
Autor:
David R. Stover, Pia M. Challita-Eid, Daniel S. Pereira, Ingrid B.J. Joseph, John Atkinson, Daulet Satpayev, Wendy Liu, Rossana Nadell, Faisal Malik, Yuriy Shostak, Ryuichi Moriya, Jimmy Ou, Peng Yang, Karen Morrison, Sher Karki, Hector Aviña, Linnette Capo, Zili An, Kendall Morrison, Arthur Raitano, Fernando Doñate
Supplemental Table 1. Quantification of ENPP3 Expression in Various Carcinomas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81085b4cbfb6ad90b94dc083d54e1849
https://doi.org/10.1158/1078-0432.22460334
https://doi.org/10.1158/1078-0432.22460334
Autor:
David R. Stover, Pia M. Challita-Eid, Daniel S. Pereira, Ingrid B.J. Joseph, John Atkinson, Daulet Satpayev, Wendy Liu, Rossana Nadell, Faisal Malik, Yuriy Shostak, Ryuichi Moriya, Jimmy Ou, Peng Yang, Karen Morrison, Sher Karki, Hector Aviña, Linnette Capo, Zili An, Kendall Morrison, Arthur Raitano, Fernando Doñate
Supplemental Figure 3A. Mapping of AGS16-7.8 binding to different ENNP3 domains. Supplemental Figure 3B. Western blots for mapping recognition of epitopes in ENPP3 ECD fragments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5387e7e6807e85977f0434db317afc
https://doi.org/10.1158/1078-0432.22460367
https://doi.org/10.1158/1078-0432.22460367
Autor:
David R. Stover, Pia M. Challita-Eid, Daniel S. Pereira, Ingrid B.J. Joseph, John Atkinson, Daulet Satpayev, Wendy Liu, Rossana Nadell, Faisal Malik, Yuriy Shostak, Ryuichi Moriya, Jimmy Ou, Peng Yang, Karen Morrison, Sher Karki, Hector Aviña, Linnette Capo, Zili An, Kendall Morrison, Arthur Raitano, Fernando Doñate
Supplemental Figure 5. Immunostaining for cleaved PARP-1 and PPH3 in tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308f0beaa45333a37d91cb29a05884ef
https://doi.org/10.1158/1078-0432.22460355
https://doi.org/10.1158/1078-0432.22460355