Phenotype-guided targeted therapy based on functional signal transduction pathway activity in recurrent ovarian cancer patients: The STAPOVER study protocol

Autor: Phyllis van der Ploeg, Cynthia SE. Hendrikse, Anna MJ. Thijs, Hans M. Westgeest, Huberdina PM. Smedts, M Caroline Vos, Mathilde Jalving, Christianne AR. Lok, Ingrid A. Boere, Maaike APC. van Ham, Petronella B. Ottevanger, Anneke M. Westermann, Constantijne H. Mom, Roy I. Lalisang, Sandrina Lambrechts, Ruud LM. Bekkers, Jurgen MJ. Piek

Publikováno v: Heliyon, Vol 10, Iss 1, Pp e23170- (2024)

Objective: Ovarian cancer is the fifth cause of cancer-related death among women. The benefit of targeted therapy for ovarian cancer patients is limited even if treatment is stratified by molecular signature. There remains a high unmet need for alter

Externí odkaz: https://doaj.org/article/ec80d08ac0c84967956ced20e2dd05ff

Ten-year experience of a national multidisciplinary tumour board for cancer and pregnancy in the Netherlands

Autor: Joosje H. Heimovaara, Ingrid A. Boere, Jorine de Haan, Kristel van Calsteren, Frédéric Amant, Lia van Zuylen, Christine A.R. Lok, C.A.R. Lok, L. van Zuylen, I.A. Boere, F. Amant, C.C.M. Beerendonk, M. Bellido-Casado, J.J. Beltman, M.E.M.M. Bos, J.J. Duvekot, C.G., Gerestein, S. Gordijn, C.J.M. de Groot, M. van Grotel, S.N. Han, B.C. Heeres, M.M. van den Heuvel-Eibrink, A. Houwink, D.R. Huitema, PhW. Koken, L.B. Koppert, P.J. Lugtenburg, P.B. Ottevanger, R.C. Painter, P.M.P. Poortmans, E.M. Roes, L. van der Scheer, C.P. Schröder, B.B.M. Suelmann, K.P.M. Suijkerbuijk, G. van Tienhoven, N.E. van Trommel, J.W. Trum, J. van der Velden, I.J.H. Vriens, P.O. Witteveen

Publikováno v: Heimovaara, J H, Boere, I A, de Haan, J, van Calsteren, K, Amant, F, van Zuylen, L, Lok, C A R, the Dutch Advisory Board for Cancer during Pregnancy, Lok, C A R, van Zuylen, L, Boere, I A, Amant, F, Beerendonk, C C M, Bellido-Casado, M, Beltman, J J, Bos, M E M M, Duvekot, J J, Gerestein, C G, Gordijn, S, de Groot, C J M, van Grotel, M, Han, S N, Heeres, B C, van den Heuvel-Eibrink, M M, Houwink, A, Huitema, D R, Koken, P, Koppert, L B, Lugtenburg, P J, Ottevanger, P B, Painter, R C, Poortmans, P M P, Roes, E M, van der Scheer, L, Schröder, C P, Suelmann, B B M, Suijkerbuijk, K P M, van Tienhoven, G, van Trommel, N E, Trum, J W, van der Velden, J, Vriens, I J H & Witteveen, P O 2022, ' Ten-year experience of a national multidisciplinary tumour board for cancer and pregnancy in the Netherlands ', European Journal of Cancer, vol. 171, pp. 13-21 . https://doi.org/10.1016/j.ejca.2022.04.040
European Journal of Cancer, 171, 13-21. Pergamon
European Journal of Cancer, 171, 13-21. Elsevier Ltd.
European Journal of Cancer, 171, 13-21. ELSEVIER SCI LTD
European Journal of Cancer, 171, 13-21
European Journal of Cancer, 171, pp. 13-21
European Journal of Cancer, 171, 13-21. Elsevier Limited

Contains fulltext : 252036.pdf (Publisher’s version ) (Closed access) BACKGROUND: Most physicians encounter pregnant women with cancer incidentally, leading to a lack of expertise or confidence to inform and treat these patients based on the most r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb870c0ecb6e659780a111f08cb40158
https://doi.org/10.1016/j.ejca.2022.04.040

The effectiveness of monotherapy with PI3K/AKT/mTOR pathway inhibitors in ovarian cancer: A meta-analysis

Autor: Ruud L.M. Bekkers, Phyllis van der Ploeg, Sandrina Lambrechts, Jurgen M.J. Piek, Hans M. Westgeest, Anna M.J. Thijs, Aniek Uittenboogaard, Anja van de Stolpe, Ingrid A. Boere

Publikováno v: Gynecologic Oncology, 163(2), 433-444. Elsevier Science

Objective. To determine the clinical benefit of monotherapy with PI3K/AKT/mTOR inhibitors in patients diagnosed with advanced or recurrent ovarian cancer and to investigate the predictive value of current PI3K/AKT/ mTOR biomarkers on therapy response

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d4a86c00b11c2413b6be3b738bbee7
https://doi.org/10.1016/j.ygyno.2021.07.008

2022-RA-598-ESGO Prognostic factors for adverse obstetric outcomes in pregnant cancer patients an update on 2174 cases registered in the INCIP registry

Autor: Charlotte Maggen, Joosje Heimovaara, Kristel van Calsteren, Elyce Cardonick, Annouschka Laenen, Roman G Shmakov, Vera Wolters, Mina Mhallem Gziri, Christianne Lok, Evgeniya Polushkina, Jeroen Blommaert, Michael Halaska, Robert Fruscio, Alvaro Cabrera-Garcia, Ingrid A Boere, Petronella Ottevanger, Giovanna Scarfone, Jorine de Haan, Frédéric Amant

Publikováno v: Fertility/Pregnancy.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e58b04c7486cb4c51caec754b223fe56
https://doi.org/10.1136/ijgc-2022-esgo.370

Management of pregnancy in women with cancer

Autor: Charlotte Maggen, Ingrid A. Boere, Elyce Cardonick, Liesbeth Lenaerts, Joosje Heimovaara, Vera E. R. A. Wolters, Frédéric Amant

Publikováno v: International Journal of Gynecological Cancer
International Journal of Gynecological Cancer, 31(3), 314-322. BMJ Publishing Group

As the incidence of cancer in pregnancy has been increasing in recent decades, more specialists are confronted with a complex oncologic–obstetric decision-making process. With the establishment of (inter)national registries, including the Internati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3fa89aab9fad6538cc5b6ca3917d6d1
https://doi.org/10.1136/ijgc-2020-001776