Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Ingrid Mai"'
Autor:
Gunilla Einecke, Lutz Fritsche, Hans-H. Neumayer, Petra Glander, Markus Giessing, Manuela Schütz, Klemens Budde, Ingrid Mai
Publikováno v:
Nephrology Dialysis Transplantation. 20:1463-1470
Recent developments have proposed the cyclosporin (CsA) concentration at 2 h post-dose (C(2)) as the best single time-point predictor of the extent of CsA exposure and as the optimal basis for monitoring immunosuppressive therapy in renal transplant
Publikováno v:
Bundesgesundheitsblatt Gesundheitsforsch.Gesundheitsschutz. 48:397-400
Im Rahmen der 12. Novelle des Arzneimittelgesetzes wurden erstmals Definitionen fur die klinische Prufung und die nichtinterventionelle Prufung im Gesetzestext verankert. Andere Begriffe, wie der systematische Heilversuch, der individuelle Heilversuc
Autor:
Ivar Roots, Bruno Frank, Klemens Budde, Ingrid Mai, Bernhard Uehleke, Steffen Bauer, Elke S. Perloff, Andreas Johne
Publikováno v:
Clinical Pharmacology & Therapeutics. 76:330-340
Objective Hyperforin (HYF) has been discussed as a potential cause of the reduction in the bioavailability of numerous drugs seen with St John's wort (SJW) comedication. This study compared the effects of 2 SJW preparations with high and low HYF cont
Autor:
Dieter Haffner, Steffen Bauer, Klemens Budde, Anne-Kathrin Pieper, Franziska Buhle, Hans-Hellmut Neumayer, Ingrid Mai, Uwe Querfeld
Publikováno v:
Nephrology Dialysis Transplantation. 19:2630-2633
Background. After renal transplantation, patients with insufficient graft function may require phosphate binders. It is still unknown if sevelamer, a new calcium-free phosphate binder, interferes with the uptake of immunosuppressants. We studied its
Autor:
Johannes Waiser, Ingrid Mai, Hans-Hellmut Neumayer, Lutz Fritsche, Torsten Slowinski, Klemens Budde, Gunilla Einecke
Publikováno v:
Nephrology Dialysis Transplantation. 19:215-222
Background. Cyclosporin A (CyA) is a drug with a narrow therapeutic window and highly variable pharmacokinetics. Therapeutic drug monitoring is essential and conventionally has been guided by trough levels (C 0 ). Recent evidence indicates that a sin
Publikováno v:
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz. 46:1061-1067
Das Interesse an Arzneimittelwechselwirkungen mit Johanniskraut (Hypericum perforatum L.) hat in den letzten Jahren eine Vielzahl von prospektiven klinischen Studien initiiert. Diese zeigten, dass eine Mehrfachgabe von Johanniskrautzubereitungen zu e
Autor:
P. Hambach, Lutz Fritsche, Ingrid Mai, Petra Glander, Klemens Budde, Johannes Waiser, K. P. Braun, H.-H. Neumayer
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 41:470-476
Objective: Mycophenolate mofetil (MMF) is routinely used as an immunosuppressant in a fixed daily dose regimen although it shows marked fluctuations in pharmacokinetics, and despite the fact that in regard to the active metabolite, mycophenolic acid
Autor:
Janusz Feber, Doris Franke, Claire LeBlanc, Miriam Hansen, Ingrid Mai, Nathalie Lepage, Guido Filler
Publikováno v:
Scopus-Elsevier
This study describes the pharmacokinetics of mycophenolate mofetil (MMF) in 15 pediatric patients with vasculitis and connective tissue disease involving the kidney. Patients included 10 with systemic lupus erythematosus (SLE), 1 with antiphospholipi
Autor:
Hans-Hellmut Neumayer, Hagen Krüger, Elke Störmer, Steffen Bauer, Ivar Roots, Andreas Johne, Ingrid Mai, Klemens Budde
Publikováno v:
British Journal of Clinical Pharmacology. 55:203-211
Aim This study investigated the effects of St John's wort extract (SJW) on the pharmacokinetics and metabolism of the immunosuppressant cyclosporin A (CSA). Methods In an open-label study, 11 renal transplant patients received 600 mg SJW extract dail
Autor:
Krikor Dikranian, Stefanie Pesditschek, John W. Olney, Suresh Govindarajalu, Mark Dzietko, Marco Sifringer, Ellen Reith, Dana Pospischil, Chrysanthy Ikonomidou, Ingrid Mai, Petra Bittigau, Kerstin Genz
Publikováno v:
Proceedings of the National Academy of Sciences. 99:15089-15094
Epilepsy is the most common neurological disorder of young humans. Each year 150,000 children in the United States experience their first seizure. Antiepileptic drugs (AEDs), used to treat seizures in children, infants, and pregnant women, cause cogn