Zobrazeno 1 - 10
of 331
pro vyhledávání: '"Ingram, N"'
Autor:
Ingram, N., Abou-Saleh, R.H., Race, Amanda D., Loadman, Paul, Bushby, R.J., Evans, S.D., Coletta, P.L.
Yes
Therapeutic microbubbles (thMBs) contain drug-filled liposomes linked to microbubbles and targeted to vascular proteins. Upon the application of a destructive ultrasound trigger, drug uptake to tumour is improved. However, the structure of t
Therapeutic microbubbles (thMBs) contain drug-filled liposomes linked to microbubbles and targeted to vascular proteins. Upon the application of a destructive ultrasound trigger, drug uptake to tumour is improved. However, the structure of t
Externí odkaz:
http://hdl.handle.net/10454/19981
Autor:
Ingram, N., McVeigh, L.E., Abou-Saleh, R.H., Batchelor, D.V.B., Loadman, Paul, McLaughlan, J.R., Markham, A.F., Evans, S.D., Coletta, P.L.
Yes
Advanced drug delivery systems, such as ultrasound-mediated drug delivery, show great promise for increasing the therapeutic index. Improvements in delivery by altering the ultrasound parameters have been studied heavily in vitro but relativ
Advanced drug delivery systems, such as ultrasound-mediated drug delivery, show great promise for increasing the therapeutic index. Improvements in delivery by altering the ultrasound parameters have been studied heavily in vitro but relativ
Externí odkaz:
http://hdl.handle.net/10454/19630
Autor:
Charalambous, A., Mico, V., McVeigh, L.E., Marston, G., Ingram, N., Volpato, M., Peyman, S.A., McLaughlan, J.R., Wierzbicki, Antonia, Loadman, Paul, Bushby, R.J., Markham, A.F., Evans, S.D., Coletta, P.L.
Yes
The hydrophobicity of a drug can be a major challenge in its development and prevents the clinical translation of highly potent anti-cancer agents. We have used a lipid-based nanoemulsion termed Lipid-Oil-Nanodroplets (LONDs) for the encapsu
The hydrophobicity of a drug can be a major challenge in its development and prevents the clinical translation of highly potent anti-cancer agents. We have used a lipid-based nanoemulsion termed Lipid-Oil-Nanodroplets (LONDs) for the encapsu
Externí odkaz:
http://hdl.handle.net/10454/18516
Autor:
Ingram, N., McVeigh, L.E., Abou-Saleh, R.H., Maynard, J., Peyman, S.A., McLaughlan, J.R., Fairclough, M., Marston, G., Valleley, E.M.A., Jimenez-Macias, J.L., Charalambous, A., Townley, W., Haddrick, M., Wierzbicki, A., Wright, A., Volpato, M., Simpson, P.B., Treanor, D.E., Thomson, N.H., Loadman, Paul, Bushby, R.J., Johnson, B.R.G., Jones, P.F., Evans, T., Freear, S., Markham, A.F., Evans, S.D., Coletta, P.L.
Yes
Most cancer patients receive chemotherapy at some stage of their treatment which makes improving the efficacy of cytotoxic drugs an ongoing and important goal. Despite large numbers of potent anti-cancer agents being developed, a major obsta
Most cancer patients receive chemotherapy at some stage of their treatment which makes improving the efficacy of cytotoxic drugs an ongoing and important goal. Despite large numbers of potent anti-cancer agents being developed, a major obsta
Externí odkaz:
http://hdl.handle.net/10454/17999
Akademický článek
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Delivery of chemotherapy drugs specifically to cancer cells raises local drug doses in tumors and therefore kills more cancer cells while reducing side effects in other tissues, thereby improving oncological and quality of life outcomes. Cubosomes, l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::1cc777969c15ec3683ff6f71237d4ad9
https://eprints.whiterose.ac.uk/189509/8/acs.molpharmaceut.2c00439.pdf
https://eprints.whiterose.ac.uk/189509/8/acs.molpharmaceut.2c00439.pdf
Akademický článek
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Autor:
Pramanik, A, Xu, Z, Shamsuddin, SH, Khaled, YS, Ingram, N, Maisey, T, Tomlinson, D, Coletta, PL, Jayne, D, Hughes, TA, Tyler, AII, Millner, PA
Nanomedicines, while having been approved for cancer therapy, present many challenges such as low stability, rapid clearance, and nonspecificity leading to off-target toxicity. Cubosomes are porous lyotropic liquid crystalline nanoparticles that have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::35ede4d2635e23ddf7ff7fb7e4bee4f4
https://eprints.whiterose.ac.uk/184492/7/acsami.1c21655.pdf
https://eprints.whiterose.ac.uk/184492/7/acsami.1c21655.pdf