Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ingo Vogt"'
Autor:
Cécile Otten, Jessica Knox, Gwénola Boulday, Mathias Eymery, Marta Haniszewski, Martin Neuenschwander, Silke Radetzki, Ingo Vogt, Kristina Hähn, Coralie De Luca, Cécile Cardoso, Sabri Hamad, Carla Igual Gil, Peter Roy, Corinne Albiges‐Rizo, Eva Faurobert, Jens P von Kries, Mónica Campillos, Elisabeth Tournier‐Lasserve, W Brent Derry, Salim Abdelilah‐Seyfried
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 10, Pp 1-17 (2018)
Abstract Cerebral cavernous malformations (CCMs) are vascular lesions in the central nervous system causing strokes and seizures which currently can only be treated through neurosurgery. The disease arises through changes in the regulatory networks o
Externí odkaz:
https://doaj.org/article/617fa245aa464ddcaa674cdeaafda0b5
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 9, p e1005111 (2016)
The molecular mechanisms that translate drug treatment into beneficial and unwanted effects are largely unknown. We present here a novel approach to detect gene-drug and gene-side effect associations based on the phenotypic similarity of drugs and si
Externí odkaz:
https://doaj.org/article/3bd24ce2ca304e35ab379a5b8ad5573a
Publikováno v:
Nucleic Acids Research
Nucleic Acids Res. 43, D900-D906 (2015)
Nucleic Acids Res. 43, D900-D906 (2015)
Perturbations of mammalian organisms including diseases, drug treatments and gene perturbations in mice affect organ systems differently. Some perturbations impair relatively few organ systems while others lead to highly heterogeneous or systemic eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c908f997dcd97e755010e77cdc38b66
https://doi.org/10.1093/nar/gku948
https://doi.org/10.1093/nar/gku948
Autor:
Jordi Mestres, Ingo Vogt
Publikováno v:
Molecular Informatics. 38:1980701
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5b4d7e0e611381569f6f7e8ce86e24f
https://doi.org/10.1002/minf.201980701
https://doi.org/10.1002/minf.201980701
Autor:
Jordi Mestres, Ingo Vogt
Publikováno v:
Molecular Informatics. 38:1900032
With the advent of increasing computational power and large-scale data acquisition, network analysis has become an attractive tool to study the organisation of complex systems and the interrelation of their constituent entities in various scientific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb601eada2983ddffe8c91b35fc42b2d
https://doi.org/10.1002/minf.201900032
https://doi.org/10.1002/minf.201900032
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 9, p e1005111 (2016)
PLoS Computational Biology
PLoS Comput. Biol. 12, DOI: 10.1371/journal.pcbi.1005111 (2016)
PLoS Computational Biology
PLoS Comput. Biol. 12, DOI: 10.1371/journal.pcbi.1005111 (2016)
The molecular mechanisms that translate drug treatment into beneficial and unwanted effects are largely unknown. We present here a novel approach to detect gene-drug and gene-side effect associations based on the phenotypic similarity of drugs and si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab5715f85ef9e89ccaa6140a2e051a11
http://europepmc.org/articles/PMC5038975?pdf=render
http://europepmc.org/articles/PMC5038975?pdf=render
Publikováno v:
Molecular Diversity. 12:25-40
We design and analyze compound selectivity sets of antagonists with differential selectivity against seven biogenic amine G-protein coupled receptors. The selectivity sets consist of a total of 267 antagonists and contain a spectrum of in part closel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140cc59e7c2511c008be92a74034f157
https://doi.org/10.1007/s11030-008-9071-2
https://doi.org/10.1007/s11030-008-9071-2
Autor:
Stefan Peters, Josef Opatrný, Peter Imbusch, Bernard Lavallé, Peter Fleer, Jochen Plötz, Rudolf Kerscher, Rainer Huhle, Raymund Buve, Hans-Jürgen Prien, Christa Wetzel, Kai-Ingo Vogt, Manuel Paulus, Paula Bruno, José Antonio Zanca
Publikováno v:
Iberoamericana. América Latina-España-Portugal, Vol 9, Iss 35, Pp 271-299 (2014)
IBEROAMERICANA, Vol. 9, Núm. 35 (2009)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407c0001f815f5dbcbd9a315aa1d7301
Publikováno v:
Genome Med. 6:52 (2014)
Genome Medicine
Genome Medicine
Background The incomplete understanding of disease causes and drug mechanisms of action often leads to ineffective drug therapies or side effects. Therefore, new approaches are needed to improve treatment decisions and to elucidate molecular mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea55d82ba1d7d319a8c5fe8145226345
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=32268
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=32268
Autor:
Ingo Vogt, José Batista, Dagmar Stumpfe, Michael Gütschow, Maxim Frizler, Jürgen Bajorath, Mihiret T. Sisay
Publikováno v:
ChemMedChem. 4:52-54
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c845c90360e7b7764bb90b787dd8d796
https://doi.org/10.1002/cmdc.200800304
https://doi.org/10.1002/cmdc.200800304