Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ingo Stammberger"'
Autor:
Tim Becker, Jan Heitkötter, Anna K. Krome, Andrea Schiefer, Kenneth Pfarr, Alexandra Ehrens, Miriam Grosse, Birthe Sandargo, Ingo Stammberger, Marc Stadler, Marc P. Hübner, Stefan Kehraus, Achim Hoerauf, Karl G. Wagner
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 386 (2024)
Toxicological studies are a part of the drug development process and the preclinical stages, for which suitable vehicles ensuring easy and safe administration are crucial. However, poor aqueous solubility of drugs complicates vehicle screening for or
Externí odkaz:
https://doaj.org/article/67c81d037ce842dc8ccd3f679297af6f
Publikováno v:
International Journal of Toxicology. 25:25-33
Receptor binding and signaling and the mitogenic potential of insulin glulisine (glulisine), regular human insulin (RHI), and Asp(B10) were compared in vivo and in vitro. Insulin and insulin-like growth factor 1 (IGF-1) receptor binding was studied w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e86ac52a38ca963221d0b76ba3b10f97
https://doi.org/10.1080/10915810500488379
https://doi.org/10.1080/10915810500488379
Publikováno v:
International Journal of Toxicology. 21:181-189
Insulin glargine (LANTUS) is a new insulin analog that has a prolonged duration of action with no pronounced peak of activity, rendering it an ideal basal insulin for the treatment of diabetes. The aim of these studies was to assess the reproductive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b797f47e4508ed101c762be8e51136c
https://doi.org/10.1080/10915810290096315
https://doi.org/10.1080/10915810290096315
Publikováno v:
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology. 103:73-78
1. In vitro , some nucleotoxic or potentially nucleotoxic agents were tested with freshly isolated liver and brain cells from chick embryos as well as with thymic cells of the rat. 2. In vivo , chicken embryos were exposed to X-rays, methyl methanesu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb16686969072556ca1c0ebe4c463f9e
https://doi.org/10.1016/0742-8413(92)90230-5
https://doi.org/10.1016/0742-8413(92)90230-5
Publikováno v:
International journal of toxicology. 21(3)
Insulin glargine (LANTUS) is a new, long-acting insulin analogue with a stable profile of action. The purpose of these studies was to evaluate the carcinogenic potential of insulin glargine in rats and mice. General toxicity studies were conducted in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e863cf021dd963e4073bc108399ed6c0
https://pubmed.ncbi.nlm.nih.gov/12055018
https://pubmed.ncbi.nlm.nih.gov/12055018