Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Ingo Schiffers"'
Autor:
Che Julius Ngwa, Rabea Stratmann, Jean Pierre Musabyimana, Kristina Pannen, Jan-Hendrik Schöbel, Marcus Frings, Ingo Schiffers, Calogero Quaranta, Steffen Koschmieder, Nicolas Chatain, Gabriele Pradel, Carsten Bolm
Publikováno v:
Tropical Medicine and Infectious Disease, Vol 7, Iss 12, p 416 (2022)
Malaria is one of the deadliest tropical diseases, especially causing havoc in children under the age of five in Africa. Although the disease is treatable, the rapid development of drug resistant parasites against frontline drugs requires the search
Externí odkaz:
https://doaj.org/article/14fb282cb32d460d82cccdcd5ace6e5d
Autor:
Ingo Schiffers, Marcus Frings, Britta Maria Kübber, Khai-Nghi Truong, Kari Rissanen, Carsten Bolm
Publikováno v:
Organic Process Research & Development. 26:2811-2822
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caaaeffd5648c84b1f6e8d17a7675ae8
https://doi.org/10.1021/acs.oprd.2c00152
https://doi.org/10.1021/acs.oprd.2c00152
Publikováno v:
Chemistry - A European Journal. 21:7705-7708
A highly stereoselective vinylogous Mukaiyama Michael reaction (VMMR) leading to α-keto phosphonate-containing γ-butenolides with two stereogenic centers is described. The presented transformation is catalyzed by a combination of a commercially ava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::521b1aba3a512114210cfb9be305436a
https://doi.org/10.1002/chem.201500861
https://doi.org/10.1002/chem.201500861
Publikováno v:
Chemistry - A European Journal. 20:1691-1700
A procedure that enables high yielding access to phosphonic γ-(hydroxyalkyl)butenolides with excellent regio-, diastereo- and enantiocontrol is reported. The simultaneous construction of up to two adjacent quaternary stereogenic centers by a catalyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba7e37d915462770182b61a4b8788e5
https://doi.org/10.1002/chem.201304331
https://doi.org/10.1002/chem.201304331
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 22(41)
A mechanochemical version of the Strecker reaction for the synthesis of α-aminonitriles was developed. The milling of aldehydes, amines, and potassium cyanide in the presence of SiO2 gave the corresponding α-aminonitriles in good to high yields. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2926af7ce1a8a64e354df9362d7fc05
https://pubmed.ncbi.nlm.nih.gov/27481327
https://pubmed.ncbi.nlm.nih.gov/27481327
Publikováno v:
Organic Letters. 14:4518-4521
A series of new thiourea catalysts prepared from natural amino acids have been applied in organocatalytic asymmetric Michael additions of α-nitrocyclohexanone to nitroalkenes. The resulting addition products are formed with excellent enantioselectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5eaf233ea5fec18097317beaf5206f1
https://doi.org/10.1021/ol302005f
https://doi.org/10.1021/ol302005f
Publikováno v:
Tetrahedron. 66:6349-6357
Readily available, low molecular cyclohexane-based organocatalysts promote highly enantioselective desymmetrizations of cyclic meso-anhydrides applying alcohols and benzyl mercaptan as nucleophiles. Both succinic and glutaric anhydrides furnished the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8817a207712b2917c9ebbcf9ec7aeba0
https://doi.org/10.1016/j.tet.2010.04.121
https://doi.org/10.1016/j.tet.2010.04.121
Publikováno v:
Tetrahedron Letters. 50:3185-3188
A novel protocol for the organocatalytic conversion of arylglyoxals into the corresponding α-hydroxy arylacetic acid methyl esters has been developed. The catalyst consists of a combination of a commercially available cinchona alkaloid derivative an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0af975f25a82ef6bba85e8bc5001d23a
https://doi.org/10.1016/j.tetlet.2009.01.114
https://doi.org/10.1016/j.tetlet.2009.01.114
Publikováno v:
Chemical Reviews. 107:5683-5712
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae6a09109b2304ce2b4de62e8373b55
https://doi.org/10.1021/cr068369f
https://doi.org/10.1021/cr068369f
Publikováno v:
Organic Process Research & Development. 11:592-597
The mechanochemical technique of ball milling has been applied to the asymmetric opening of meso-anhydrides, mediated by the cinchona alkaloid quinidine. A simple workup procedure affords the products, optically active dicarboxylic acid monoesters, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c0de0364e432cd31992f8028370d6c3
https://doi.org/10.1021/op6002743
https://doi.org/10.1021/op6002743