Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ingo M. Irmler"'
Autor:
Bianca Hoffmann, Carl-Magnus Svensson, Maria Straßburger, Björn Gebser, Ingo M. Irmler, Thomas Kamradt, Hans Peter Saluz, Marc Thilo Figge
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The assessment of bone damage is required to evaluate disease severity and treatment efficacy both in arthritis patients and in experimental arthritis models. Today there is still a lack of in vivo methods that enable the quantification of a
Externí odkaz:
https://doaj.org/article/cacc0218165e466c83adae775fca26db
Autor:
Jan Dudeck, Ralf Stumm, Norman Häfner, Isabel Meininger, Sebastian Drube, Christiane Göpfert, Anna-Lena Müller, Anne Dudeck, Ingo M. Irmler, Matthias Gaestel, Mandy Beyer, Franziska Weber, Dagmar Schütz, Florian Kraft, Thomas Kamradt, Tatiana Yakovleva
Publikováno v:
The Journal of Immunology. 197:3662-3668
The IL-1R family member IL-33R mediates Fcε-receptor-I (FcεRI)-independent activation of mast cells leading to NF-κB activation and consequently the production of cytokines. IL-33 also induces the activation of MAPKs, such as p38. We aimed to defi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c919ea09484c3271689f836a56a2ac
https://doi.org/10.4049/jimmunol.1600658
https://doi.org/10.4049/jimmunol.1600658
Autor:
Maria Straßburger, Ingo M. Irmler, Carl-Magnus Svensson, Bianca Hoffmann, Marc Thilo Figge, Hans Peter Saluz
Publikováno v:
Scientific Reports
The use of animal models of arthritis is a key component in the evaluation of therapeutic strategies against the human disease rheumatoid arthritis (RA). Here we present quantitative measurements of bone degradation characterised by the cortical bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c6b4a7190472585605d6505414f07c
http://europepmc.org/articles/PMC5349516
http://europepmc.org/articles/PMC5349516
Autor:
Thomas Opfermann, Philipp Grosse-Gehling, M. Khalid, Thomas Kamradt, Hans-Peter Saluz, Jörg Steinbach, Lydia Würbach, Martin Walther, Stephan Preusche, Peter Gebhardt, Ingo M. Irmler
Publikováno v:
Applied Radiation and Isotopes. 69:852-857
We examined the production, separation, and characterization of (89)Zr, including supplementation of a commercial Cyclone(®) 18/9 with a self-made Solid Target System (STS). Obtained [(89)Zr]Zr-oxalate was used for the labeling of anti-B cell antibo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2f80cb0482597c02c23207d9ae5c5a
https://doi.org/10.1016/j.apradiso.2011.02.040
https://doi.org/10.1016/j.apradiso.2011.02.040
Publikováno v:
Annals of the Rheumatic Diseases
Objectives Clinical evidence suggests that neurological lesions can protect from arthritis. Acute cerebral ischaemia induces severe immunosuppression, resulting in enhanced susceptibility to infections. We aimed to determine if stroke-induced immunos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2323b0ad5b9ffc83cf89e65b9af801d5
https://pubmed.ncbi.nlm.nih.gov/24326006
https://pubmed.ncbi.nlm.nih.gov/24326006
Autor:
Thomas Kamradt, Peter Gebhardt, Rolf Bräuer, Thomas Opfermann, Ingo M. Irmler, Hans Peter Saluz, Mieczyslaw Gajda
Publikováno v:
Arthritis Research & Therapy
Introduction The purpose of this work was to establish and validate combined small animal positron emission tomography - computed tomography (PET/CT) as a new in vivo imaging method for visualisation and quantification of joint inflammation. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d26f623947d71e432b18a345e31141
https://doi.org/10.1186/ar3176
https://doi.org/10.1186/ar3176
Autor:
Jürgen Bernhagen, Christina Pfirschke, Uta Schurigt, Rolf Bräuer, Marion Hückel, Tobias Janik, Ria Baumgrass, Ingo M. Irmler, Mieczyslaw Gajda
Publikováno v:
Arthritis and rheumatism. 58(10)
Objective Interactions of immune cells, such as activated T helper cells, with fibroblast-like synoviocytes (FLS) play a crucial role in the joint destruction during human rheumatoid arthritis (RA). This study was undertaken to investigate the expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b70da158f44e29c6e455824aa66db25
https://pubmed.ncbi.nlm.nih.gov/18821693
https://pubmed.ncbi.nlm.nih.gov/18821693
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 179(9)
Proinflammatory Th1 responses are believed to be involved in the induction and perpetuation of rheumatoid arthritis. However, the role of IFN-γ, the major cytokine produced by Th1 cells, is still incompletely defined. In the present study, we invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a8fb9748e5e4ef71424c75900200f85
https://pubmed.ncbi.nlm.nih.gov/17947698
https://pubmed.ncbi.nlm.nih.gov/17947698
Autor:
Philipp Grosse-Gehling, Thomas Kamradt, Hans-Peter Saluz, Stephan Preusche, Jörg Steinbach, Peter Gebhardt, Ingo M. Irmler, Thomas Opfermann, Martin Walther, Lydia Würbach
Publikováno v:
Nuclear Medicine and Biology. 37:697
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b4a04d138e2a5fbf242a40026a9dd72
https://doi.org/10.1016/j.nucmedbio.2010.04.032
https://doi.org/10.1016/j.nucmedbio.2010.04.032