Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Ingo G H Schmidt-Wolf"'
Autor:
Jingjing Pu, Ting Liu, Amit Sharma, Liping Jiang, Feng Wei, Xiubao Ren, Ingo G. H. Schmidt-Wolf, Jian Hou
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-29 (2024)
Abstract The basic idea of modulating the immune system to better recognize and fight tumor cells has led to the successful introduction of adoptive cellular immunotherapy (ACT). ACT-based treatment regimens, in which the patient's own immune cells a
Externí odkaz:
https://doaj.org/article/285baec50f1c434e8a0e2bf8bf15f536
Autor:
Tikam Chand Dakal, Ravi Bhushan, Caiming Xu, Bhana Ram Gadi, Swaranjit Singh Cameotra, Vikas Yadav, Jarek Maciaczyk, Ingo G. H. Schmidt‐Wolf, Abhishek Kumar, Amit Sharma
Publikováno v:
MedComm, Vol 5, Iss 10, Pp n/a-n/a (2024)
Abstract Cancer stem cells (CSCs) are widely acknowledged as the drivers of tumor initiation, epithelial‐mesenchymal transition (EMT) progression, and metastasis. Originating from both hematologic and solid malignancies, CSCs exhibit quiescence, pl
Externí odkaz:
https://doaj.org/article/beddc62bbfd64063b04d64c10b0aca74
Autor:
Chunxia Zhao, Yulu Wang, Huan Wang, Amit Sharma, Yun Wu, Ingo G. H. Schmidt-Wolf, Zifeng Wang
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Background Acute myeloid leukemia, constituting a majority of leukemias, grapples with a 24% 5-year survival rate. Recent strides in research have unveiled fresh targets for drug therapies. LIM-only, a pivotal transcription factor within LIM
Externí odkaz:
https://doaj.org/article/e63cf600083a45daa69c4e3f99bf7278
Autor:
Jingjing Pu, Ting Liu, Xuzhen Wang, Amit Sharma, Ingo G. H. Schmidt-Wolf, Liping Jiang, Jian Hou
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-19 (2024)
Abstract Histone deacetylase inhibitors (HDACis) are a significant category of pharmaceuticals that have developed in the past two decades to treat multiple myeloma. Four drugs in this category have received approval from the U.S. Food and Drug Admin
Externí odkaz:
https://doaj.org/article/b434a3dee12c430db83ac99420578c56
Autor:
Aliona Wöhler, Sabine K. Gries, Rebekka J. S. Salzmann, Christina Krötz, Bingduo Wang, Paula Müller, Angelina Klein, Ingo G. H. Schmidt‐Wolf, Sebastian Schaaf, Robert Schwab, Veronika Lukacs‐Kornek, Arnulf G. Willms, Miroslaw T. Kornek
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 9, Pp n/a-n/a (2024)
Abstract Despite significant progress in the medical field, there is still a pressing need for minimal‐invasive tools to assist with decision‐making, especially in cases of polytrauma. Our team explored the potential of serum‐derived large extr
Externí odkaz:
https://doaj.org/article/913c585286314a4d9e7d8c5b654fe34d
Autor:
Desheng Lu, Jerry X Liu, Tomoyuki Endo, Haowen Zhou, Shiyin Yao, Karl Willert, Ingo G H Schmidt-Wolf, Thomas J Kipps, Dennis A Carson
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8294 (2009)
BACKGROUND:Aberrant activation of Wnt/beta-catenin signaling promotes the development of several cancers. It has been demonstrated that the Wnt signaling pathway is activated in chronic lymphocytic leukemia (CLL) cells, and that uncontrolled Wnt/beta
Externí odkaz:
https://doaj.org/article/209b7c9f1e9a401ebf47daad7ff7a248
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/dcadfd0c42334bd4b8511831ccf46389
Autor:
Tikam Chand Dakal, Bhanupriya Dhabhai, Anuja Pant, Kareena Moar, Kanika Chaudhary, Vikas Yadav, Vipin Ranga, Narendra Kumar Sharma, Abhishek Kumar, Pawan Kumar Maurya, Jarek Maciaczyk, Ingo G. H. Schmidt‐Wolf, Amit Sharma
Publikováno v:
MedComm, Vol 5, Iss 6, Pp n/a-n/a (2024)
Abstract Cancer, being the most formidable ailment, has had a profound impact on the human health. The disease is primarily associated with genetic mutations that impact oncogenes and tumor suppressor genes (TSGs). Recently, growing evidence have sho
Externí odkaz:
https://doaj.org/article/174e59053f014df09c974f1154bd9b77
Autor:
Amit Sharma, Yulu Wang, Fangfang Ge, Peng Chen, Tikam Chand Dakal, Maria Stella Carro, Ingo G. H. Schmidt-Wolf, Jarek Maciaczyk
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Glioblastoma multiforme (GBM) is probably the only tumor in which a unique epigenetic alteration, namely methylation of the MGMT gene, possesses direct clinical relevance. Now with the emergence of aberrant N6 methyladenosine (m6A) modificat
Externí odkaz:
https://doaj.org/article/5dbfe449cc4c4b0fbcf2214653ccfe50
Autor:
Yutao Li, Amit Sharma, Michèle J. Hoffmann, Dirk Skowasch, Markus Essler, Hans Weiher, Ingo G. H. Schmidt-Wolf
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionA multitude of findings from cell cultures and animal studies are available to support the anti-cancer properties of cannabidiol (CBD). Since CBD acts on multiple molecular targets, its clinical adaptation, especially in combination with
Externí odkaz:
https://doaj.org/article/bfc97979b5284464be438b1f21ebb638