Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ingo Focken"'
Autor:
Norbert Furtmann, Marion Schneider, Nadja Spindler, Bjoern Steinmann, Ziyu Li, Ingo Focken, Joachim Meyer, Dilyana Dimova, Katja Kroll, Wulf Dirk Leuschner, Audrey Debeaumont, Magali Mathieu, Christian Lange, Werner Dittrich, Jochen Kruip, Thorsten Schmidt, Joerg Birkenfeld
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Next-generation multi-specific antibody therapeutics (MSATs) are engineered to combine several functional activities into one molecule to provide higher efficacy compared to conventional, mono-specific antibody therapeutics. However, highly engineere
Externí odkaz:
https://doaj.org/article/98e82558dbcc41848215d30e62e1cd5e
Autor:
Delphine Valente, Christine Mauriac, Thorsten Schmidt, Ingo Focken, Jochen Beninga, Brian Mackness, Huawei Qiu, Pascale Vicat, Abdullah Kandira, Katarina Radošević, Srini Rao, John Darbyshire, Mostafa Kabiri
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Monoclonal antibodies (mAbs) are among the fastest growing and most effective therapies for myriad diseases. Multispecific antibodies are an emerging class of novel therapeutics that can target more than one tumor- or immune-associated modulators per
Externí odkaz:
https://doaj.org/article/131fb11c1c2b4c5080fd734830439d0d
Autor:
Rebecca Broeckel, Julie M Fox, Nicole Haese, Craig N Kreklywich, Soila Sukulpovi-Petty, Alfred Legasse, Patricia P Smith, Michael Denton, Carsten Corvey, Shiv Krishnan, Lois M A Colgin, Rebecca M Ducore, Anne D Lewis, Michael K Axthelm, Marie Mandron, Pierre Cortez, Jonathan Rothblatt, Ercole Rao, Ingo Focken, Kara Carter, Gopal Sapparapau, James E Crowe, Michael S Diamond, Daniel N Streblow
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 6, p e0005637 (2017)
Chikungunya virus (CHIKV) is a mosquito-borne virus that causes a febrile syndrome in humans associated with acute and chronic debilitating joint and muscle pain. Currently no licensed vaccines or therapeutics are available to prevent or treat CHIKV
Externí odkaz:
https://doaj.org/article/5f7ecbe755064591abb3daf909919650
Autor:
Audrey Debeaumont, Joachim Meyer, Wulf Dirk Leuschner, Jochen Kruip, Joerg Birkenfeld, Nadja Spindler, Norbert Furtmann, Katja Kroll, Ingo Focken, Bjoern Steinmann, Magali Mathieu, Werner Dittrich, Christian M. Lange, Dilyana Dimova, Ziyu Li, Thorsten Schmidt, M. Schneider
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Next-generation multi-specific antibody therapeutics (MSATs) are engineered to combine several functional activities into one molecule to provide higher efficacy compared to conventional, mono-specific antibody therapeutics. However, highly engineere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb39be2d54ff87cd04ff0fa33366b6ed
https://doi.org/10.1080/19420862.2021.1955433
https://doi.org/10.1080/19420862.2021.1955433
Autor:
Richard H. Kimura, Ataya Sathirachinda, Sharon S. Hori, Arutselvan Natarajan, Jochen Kruip, Chantal Carrez, Susanta K. Sarkar, Ohad Ilovich, Ingo Focken, Mathias Gebauer, Ingrid Sassoon, Veronique Blanc, Sanjiv S. Gambhir, Christian Lange, Ananth Srinivasan
Publikováno v:
Radiology. 276:191-198
To develop and compare three copper 64 ((64)Cu)-labeled antibody fragments derived from a CA6-targeting antibody (huDS6) as immuno-positron emission tomography (immuno-PET)-based companion diagnostic agents for an antibody-drug conjugate by using huD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f9a88bb811afc2d2d29b074f4e578c
https://doi.org/10.1148/radiol.15140058
https://doi.org/10.1148/radiol.15140058
Autor:
Lois M. A. Colgin, Carsten Corvey, Patricia P. Smith, Michael K. Axthelm, Pierre Cortez, Jonathan Rothblatt, Marie Mandron, Julie M. Fox, Michael Denton, Rebecca Broeckel, Ercole Rao, Michael S. Diamond, Daniel N. Streblow, Craig N. Kreklywich, Ingo Focken, Shiv Krishnan, Alfred W. Legasse, Gopal Sapparapau, Anne D. Lewis, James E. Crowe, Soila Sukulpovi-Petty, Kara Carter, Rebecca M. Ducore, Nicole N. Haese
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 11, Iss 6, p e0005637 (2017)
PLoS Neglected Tropical Diseases, Vol 11, Iss 6, p e0005637 (2017)
Chikungunya virus (CHIKV) is a mosquito-borne virus that causes a febrile syndrome in humans associated with acute and chronic debilitating joint and muscle pain. Currently no licensed vaccines or therapeutics are available to prevent or treat CHIKV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1c78c8c79e62524034600181fe4f333
https://doi.org/10.1371/journal.pntd.0005637
https://doi.org/10.1371/journal.pntd.0005637
Autor:
Katrin Schroeter, Andreas W. Herling, Zoller Gerhard, Dieter Schmoll, Sven Ruf, Marco Müller, Guido Haschke, Stefanie Keil, Ingo Focken, Maike Glien
Publikováno v:
Journal of medicinal chemistry. 53(24)
Acetyl CoA carboxylase isoforms 1 and 2 (ACC1/2) are key enzymes of fat utilization and their inhibition is considered to improve aspects of the metabolic syndrome. To identify pharmacological inhibitors of ACC1/2, a high throughput screen was perfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::789b9f1127212fb7e9be9880bf1ee320
https://pubmed.ncbi.nlm.nih.gov/21082864
https://pubmed.ncbi.nlm.nih.gov/21082864
Autor:
Stefan Bartoschek, Siegfried Stengelin, Christian Griesinger, K. Ulrich Wendt, Teresa Carlomagno, Viktoria Dietrich, Thomas Klabunde, Ingo Focken, Elisabeth Defossa
Publikováno v:
Angewandte Chemie (International ed. in English). 49(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12269e5990be5b20aaaf3d7842b6ae83
https://pubmed.ncbi.nlm.nih.gov/20084646
https://pubmed.ncbi.nlm.nih.gov/20084646