Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Ingo Drexler"'
Autor:
Giuseppe Andreacchio, Ylenia Longo, Sara Moreno Mascaraque, Kartikan Anandasothy, Sarah Tofan, Esma Özün, Lena Wilschrey, Johannes Ptok, Dung T. Huynh, Joen Luirink, Ingo Drexler
Publikováno v:
Vaccines, Vol 12, Iss 8, p 944 (2024)
Chlamydia trachomatis remains a major global health problem with increasing infection rates, requiring innovative vaccine solutions. Modified Vaccinia Virus Ankara (MVA) is a well-established, safe and highly immunogenic vaccine vector, making it a p
Externí odkaz:
https://doaj.org/article/3bda0ec5f9ad422b8e589baa61351000
Autor:
Ylenia Longo, Sara Moreno Mascaraque, Giuseppe Andreacchio, Julia Werner, Ichiro Katahira, Elena De Marchi, Anna Pegoraro, Robert Jan Lebbink, Karl Köhrer, Patrick Petzsch, Ronny Tao, Francesco Di Virgilio, Elena Adinolfi, Ingo Drexler
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionModified Vaccinia Virus Ankara (MVA) is a safe vaccine vector inducing long- lasting and potent immune responses. MVA-mediated CD8+T cell responses are optimally induced, if both, direct- and cross-presentation of viral or recombinant ant
Externí odkaz:
https://doaj.org/article/c51d0799a12d4c9e9a19762506b18869
Autor:
Chaohui Lin, Edmund Osei Kuffour, Nina V. Fuchs, Christoph G.W. Gertzen, Jesko Kaiser, Maximilian Hirschenberger, Xiao Tang, Haifeng C. Xu, Oliver Michel, Ronny Tao, Alexandra Haase, Ulrich Martin, Thomas Kurz, Ingo Drexler, Boris Görg, Philipp A. Lang, Tom Luedde, Konstantin M.J. Sparrer, Holger Gohlke, Renate König, Carsten Münk
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113277- (2023)
Summary: Sensing of human immunodeficiency virus type 1 (HIV-1) DNA is mediated by the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) signaling axis. Signal transduction and regulation of this cascade is achieved by post-translat
Externí odkaz:
https://doaj.org/article/a3e194c999a94c19ad46494fc14d84d4
Autor:
Toni L. Meister, Ronny Tao, Yannick Brüggemann, Daniel Todt, Joerg Steinmann, Joerg Timm, Ingo Drexler, Eike Steinmann
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 1, Pp 189-192 (2023)
Increasing nonzoonotic human monkeypox virus (MPXV) infections urge reevaluation of inactivation strategies. We demonstrate efficient inactivation of MPXV by 2 World Health Organization‒recommended alcohol-based hand rub solutions. When compared wi
Externí odkaz:
https://doaj.org/article/4c39aaf2a3d64dd2adf54adce5bbc592
Autor:
Lisa Müller, Marcel Andrée, Wiebke Moskorz, Ingo Drexler, Sandra Hauka, Johannes Ptok, Lara Walotka, Ramona Grothmann, Jonas Hillebrandt, Anastasia Ritchie, Laura Peter, Andreas Walker, Jörg Timm, Ortwin Adams, Heiner Schaal
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
We provide follow-up data on the humoral immune response after COVID-19 vaccinations of two distinct cohorts aged below 60 and over 80 years to screen for age-related differences in the longevity and magnitude of the induction of the antibody respons
Externí odkaz:
https://doaj.org/article/22f687e3b17c44a8a83efd4129099116
Autor:
Lisa Müller, Marcel Andrée, Philipp Niklas Ostermann, Nathalie Jazmati, Greta Flüh, Johannes C. Fischer, Edwin Bölke, Eva Heger, Kanika Vanshylla, Florian Klein, Hilmar Wisplinghoff, Heiner Schaal, Ingo Drexler, Andreas Walker, Ortwin Adams, Jörg Timm
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Prophylactic vaccination against SARS-CoV-2 is one of the most important measures to contain the COVID-19 pandemic. Recently, break-through infections following vaccination against this virus have been reported. Here, we describe the humoral immune r
Externí odkaz:
https://doaj.org/article/4156753869454f42872b72dd7dd6974a
Publikováno v:
Virology Journal, Vol 16, Iss 1, Pp 1-12 (2019)
Abstract Background Recombinant Modified Vaccinia Virus Ankara has been employed as a safe and potent viral vector vaccine against infectious diseases and cancer. We generated recMVAs encoding norovirus GII.4 genotype capsid protein by using a marker
Externí odkaz:
https://doaj.org/article/8d3c0c1ba9a44c96b1e315f9540aa39a
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Modified Vaccinia virus Ankara (MVA) is an attenuated strain of vaccinia virus and currently under investigation as a promising vaccine vector against infectious diseases and cancer. MVA acquired mutations in host range and immunomodulatory genes, re
Externí odkaz:
https://doaj.org/article/7314e9e72c1b4be88217cc471438a211
Autor:
Sha Tao, Ingo Drexler
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Innate immune cells are the “doorkeepers” in the immune system and are important for the initiation of protective vaccine responses against infection. Being an essential regulatory component of the immune system in these cells, autophagy not only
Externí odkaz:
https://doaj.org/article/e78b98010f0b4e84952fa06a91ec0e11
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Cytotoxic CD8+ T cell (CTL) responses play an essential role in antiviral immunity. Here, we focused on the activation of CTL which recognize epitopes derived from viral or recombinant antigens with either early or late expression kinetics after infe
Externí odkaz:
https://doaj.org/article/502d914d24604e97a2400f8208269619