Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Ingo B, Leibiger"'
Autor:
Francesca Lazzeri-Barcelo, Nuria Oliva-Vilarnau, Marion Baniol, Barbara Leibiger, Olaf Bergmann, Volker M. Lauschke, Ingo B. Leibiger, Noah Moruzzi, Per-Olof Berggren
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Longitudinal monitoring of liver function in vivo is hindered by the lack of high-resolution non-invasive imaging techniques. Using the anterior chamber of the mouse eye as a transplantation site, we have established a platform for longitudi
Externí odkaz:
https://doaj.org/article/2eda5aaab39e4b1b93164e67176e1475
Autor:
Robert Bränström, Pim P. van Krieken, Robin Fröbom, C. Christofer Juhlin, Ivan Shabo, Barbara Leibiger, Ingo B. Leibiger, Per-Olof Berggren, Craig A. Aspinwall
Publikováno v:
Cell Transplantation, Vol 33 (2024)
The parathyroid cell is a vital regulator of extracellular calcium levels, operating through the secretion of parathyroid hormone (PTH). Despite its importance, the regulation of PTH secretion remains complex and not fully understood, representing a
Externí odkaz:
https://doaj.org/article/e08b538003074edf8f6c2ca62bcfbaf1
Expression of truncated Kir6.2 promotes insertion of functionally inverted ATP-sensitive K+ channels
Autor:
Benjamin A. Heitz, Robert Bränström, Wei Yang, Yiding Huang, Tilo Moede, Ingo B. Leibiger, Barbara Leibiger, Liu Qi Chen, Jia Yu, Shao-Nian Yang, Olof Larsson, S. Scott Saavedra, Per-Olof Berggren, Craig A. Aspinwall
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract ATP-sensitive K+ (KATP) channels couple cellular metabolism to electrical activity in many cell types. Wild-type KATP channels are comprised of four pore forming (Kir6.x) and four regulatory (sulfonylurea receptor, SURx) subunits that each c
Externí odkaz:
https://doaj.org/article/87b22a90ce764dbc9e3214f3647c135f
Autor:
Jia Yu, Barbara Leibiger, Shao-Nian Yang, Stephen B. Shears, Ingo B. Leibiger, Per-Olof Berggren, Christopher J. Barker
Publikováno v:
Biomolecules, Vol 13, Iss 6, p 885 (2023)
Multiple inositol polyphosphate phosphatase (MINPP1) is an enigmatic enzyme that is responsible for the metabolism of inositol hexakisphosphate (InsP6) and inositol 1,3,4,5,6 pentakisphosphate (Ins(1,3,4,5,6)P5 in mammalian cells, despite being restr
Externí odkaz:
https://doaj.org/article/6ffb397ad7494abf9d89ea895e39da7c
Autor:
Robert Bränström, Erik Berglund, Robin Fröbom, Ingo B. Leibiger, Barbara Leibiger, Craig A. Aspinwall, Olof Larsson, Per-Olof Berggren
Publikováno v:
Biochemistry and Biophysics Reports, Vol 30, Iss , Pp 101260- (2022)
Background: The ATP-sensitive K+ (K(ATP)) channel is found in a variety of tissues extending from the heart and vascular smooth muscles to the endocrine pancreas and brain. Common to all K(ATP) channels is the pore-forming subunit Kir6.x, a member of
Externí odkaz:
https://doaj.org/article/04ad32cb51f140e8ac20d35b11721ce8
Autor:
Ingo B. Leibiger, Per-Olof Berggren
Publikováno v:
Molecular Metabolism, Vol 6, Iss 9, Pp 1002-1009 (2017)
Background: Diabetes mellitus has reached epidemic proportions and requires new strategies for treatment. Unfortunately, the efficacy of treatment regimens on maintaining/re-gaining functional beta cell mass can, at the present, only be determined in
Externí odkaz:
https://doaj.org/article/2ce08552737e414b85c6fc205b916e41
Autor:
Barbara Leibiger, Tilo Moede, Ismael Valladolid-Acebes, Meike Paschen, Montse Visa, Ingo B. Leibiger, Per-Olof Berggren
Publikováno v:
Metabolites, Vol 11, Iss 6, p 387 (2021)
The pancreatic islets of Langerhans consist of endocrine cells that secrete peptide hormones into the blood circulation in response to metabolic stimuli. When transplanted into the anterior chamber of the eye (ACE), pancreatic islets engraft and main
Externí odkaz:
https://doaj.org/article/6669e463aece4bb4b111a710db503a85
Autor:
Barbara Leibiger, Tilo Moede, Meike Paschen, Na-Oh Yunn, Jong Hoon Lim, Sung Ho Ryu, Teresa Pereira, Per-Olof Berggren, Ingo B. Leibiger
Publikováno v:
Cell Reports, Vol 13, Iss 1, Pp 15-22 (2015)
Insulin resistance is a syndrome that affects multiple insulin target tissues, each having different biological functions regulated by insulin. A remaining question is to mechanistically explain how an insulin target cell/tissue can be insulin resist
Externí odkaz:
https://doaj.org/article/579433b1afa946ba860b86f60e89c2ef
Publikováno v:
Methods in Molecular Biology ISBN: 9781071628065
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9292a196338575ebbd84e3626c83f7a7
https://doi.org/10.1007/978-1-0716-2807-2_2
https://doi.org/10.1007/978-1-0716-2807-2_2
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2592
The anterior chamber of the eye is a highly vascularized and innervated location that is also particularly rich in oxygen and immune privileged. This uncommon transplantation site offers unique possibilities for the observation of the transplanted ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29a95cc4e1c66d7e5879ec8a0a861dc3
https://pubmed.ncbi.nlm.nih.gov/36507983
https://pubmed.ncbi.nlm.nih.gov/36507983