Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ingo Amm"'
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140363 (2015)
The Saccharomyces cerevisiae heat shock proteins Hsp31, Hsp32, Hsp33 and Hsp34 belong to the DJ-1/ThiJ/PfpI superfamily which includes the human protein DJ-1 (PARK7) as the most prominent member. Mutations in the DJ-1 gene are directly linked to auto
Externí odkaz:
https://doaj.org/article/a8157dc66a2b463b86e36946bb0c5b58
Autor:
Ingo Amm, Marion Weberruss, Andrea Hellwig, Johannes Schwarz, Marianna Tatarek-Nossol, Christian Lüchtenborg, Martina Kallas, Britta Brügger, Ed Hurt, Wolfram Antonin
Publikováno v:
Journal of Cell Biology. 222
Nuclear pore complexes (NPCs) are embedded in the nuclear envelope and built from ∼30 different nucleoporins (Nups) in multiple copies, few are integral membrane proteins. One of these transmembrane nucleoporins, Ndc1, is thought to function in NPC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9fc1d4319a3ca8a72c8728ff93070b5
https://doi.org/10.1083/jcb.202210059
https://doi.org/10.1083/jcb.202210059
Autor:
Ingo Amm, Marion H Weberruss, Andrea Hellwig, Johannes Schwarz, Marianna Tatarek-Nossol, Christian Lüchtenborg, Martina Kallas, Britta Brügger, Ed Hurt, Wolfram Antonin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d07a16f6d061fee2b1048f26382c773e
https://doi.org/10.15252/rc.2022103944
https://doi.org/10.15252/rc.2022103944
Autor:
Ingo Amm, Marion Weberruss, Andrea Hellwig, Johannes Schwarz, Marianna Tatarek-Nossol, Christian Lüchtenborg, Martina Kallas, Britta Brügger, Ed Hurt, Wolfram Antonin
The nuclear pore complex (NPC) embedded in the double nuclear membrane is built from ~30 different nucleoporins (Nups) in multiple copies, of which a few are integral nuclear membrane proteins. One of these transmembrane Nups is Ndc1, which is though
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6537d6c933fb4590404bb2766c6bdd22
https://doi.org/10.1101/2022.07.31.501833
https://doi.org/10.1101/2022.07.31.501833
Publikováno v:
Analytical Biochemistry. 515:14-21
Protein misfolding and protein aggregation are causes of severe diseases as neurodegenerative disorders, diabetes and cancer. Therefore, the cell has to constantly monitor the folding status of its proteome. Chaperones and components of the ubiquitin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6402dcc16812bd4aa6b2cae148428bc0
https://doi.org/10.1016/j.ab.2016.09.012
https://doi.org/10.1016/j.ab.2016.09.012
Publikováno v:
Journal of Biological Chemistry. 290:4677-4687
For the assembly of protein complexes in the cell, the presence of stoichiometric amounts of the respective protein subunits is of utmost importance. A surplus of any of the subunits may trigger unspecific and harmful protein interactions and has to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e47f056d7969a9fcd31a365e940a7a59
https://doi.org/10.1074/jbc.m114.596064
https://doi.org/10.1074/jbc.m114.596064
Autor:
Ingo Amm, Dieter H. Wolf
Publikováno v:
FEBS letters. 590(12)
Most misfolded cytosolic proteins in the cell are eliminated by the ubiquitin-proteasome system. In yeast, polyubiquitination of misfolded cytosolic proteins is triggered mainly by the action of two ubiquitin ligases Ubr1, formerly discovered as reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd45a781e986dc2cddb973700fadc89
https://pubmed.ncbi.nlm.nih.gov/27173001
https://pubmed.ncbi.nlm.nih.gov/27173001
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 10, p e0140363 (2015)
PLoS ONE, Vol 10, Iss 10, p e0140363 (2015)
The Saccharomyces cerevisiae heat shock proteins Hsp31, Hsp32, Hsp33 and Hsp34 belong to the DJ-1/ThiJ/PfpI superfamily which includes the human protein DJ-1 (PARK7) as the most prominent member. Mutations in the DJ-1 gene are directly linked to auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1bfc0498e08b29272d75e1d0bafc2f
https://pubmed.ncbi.nlm.nih.gov/26466368
https://pubmed.ncbi.nlm.nih.gov/26466368
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. (1):182-196
Mistakes are part of our world and constantly occurring. Due to transcriptional and translational failures, genomic mutations or diverse stress conditions like oxidation or heat misfolded proteins are permanently produced in every compartment of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da5daca3f5ba62e1f92e17320542899