Systemic Immunotherapy with Micellar Resiquimod-Polymer Conjugates Triggers a Robust Antitumor Response in a Breast Cancer Model.

Autor: Kakwere H; Molecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Palo Alto, CA, 94305, USA., Zhang H; Molecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Palo Alto, CA, 94305, USA., Ingham ES; Department of Biomedical Engineering, University of California (Davis), Davis, CA, 95616, USA., Nura-Raie M; Molecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Palo Alto, CA, 94305, USA., Tumbale SK; Molecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Palo Alto, CA, 94305, USA., Allen R; Department of Biomedical Engineering, University of California (Davis), Davis, CA, 95616, USA., Tam SM; Department of Biomedical Engineering, University of California (Davis), Davis, CA, 95616, USA., Wu B; Molecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Palo Alto, CA, 94305, USA., Liu C; Molecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Palo Alto, CA, 94305, USA., Kheirolomoom A; Molecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Palo Alto, CA, 94305, USA., Fite BZ; Molecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Palo Alto, CA, 94305, USA., Ilovitsh A; Molecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Palo Alto, CA, 94305, USA., Lewis JS; Department of Biomedical Engineering, University of California (Davis), Davis, CA, 95616, USA., Ferrara KW; Molecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University, Palo Alto, CA, 94305, USA.

Publikováno v: Advanced healthcare materials [Adv Healthc Mater] 2021 May; Vol. 10 (10), pp. e2100008. Date of Electronic Publication: 2021 Mar 01.

Immune modulation resulting from MR-guided high intensity focused ultrasound in a model of murine breast cancer.

Autor: Fite BZ; Department of Radiology, Stanford University, 3165 Porter Dr, Palo Alto, CA, 94305, USA., Wang J; Department of Radiology, Stanford University, 3165 Porter Dr, Palo Alto, CA, 94305, USA., Kare AJ; Department of Radiology, Stanford University, 3165 Porter Dr, Palo Alto, CA, 94305, USA.; Department of Biomedical Engineering, Stanford University, Palo Alto, CA, 94305, USA., Ilovitsh A; Department of Radiology, Stanford University, 3165 Porter Dr, Palo Alto, CA, 94305, USA., Chavez M; Department of Biomedical Engineering, Stanford University, Palo Alto, CA, 94305, USA., Ilovitsh T; Department of Radiology, Stanford University, 3165 Porter Dr, Palo Alto, CA, 94305, USA., Zhang N; Department of Radiology, Stanford University, 3165 Porter Dr, Palo Alto, CA, 94305, USA., Chen W; Department of Radiology, Stanford University, 3165 Porter Dr, Palo Alto, CA, 94305, USA., Robinson E; Department of Radiology, Stanford University, 3165 Porter Dr, Palo Alto, CA, 94305, USA., Zhang H; Department of Biomedical Engineering, University of California Davis, Davis, CA, 95616, USA., Kheirolomoom A; Department of Radiology, Stanford University, 3165 Porter Dr, Palo Alto, CA, 94305, USA., Silvestrini MT; Department of Biomedical Engineering, University of California Davis, Davis, CA, 95616, USA., Ingham ES; Department of Biomedical Engineering, University of California Davis, Davis, CA, 95616, USA., Mahakian LM; Department of Biomedical Engineering, University of California Davis, Davis, CA, 95616, USA., Tam SM; Department of Biomedical Engineering, University of California Davis, Davis, CA, 95616, USA., Davis RR; Department of Pathology and Laboratory Medicine, School of Medicine, University of California Davis, Sacramento, CA, 95817, USA., Tepper CG; Department of Biochemistry and Molecular Medicine, School of Medicine, University of California Davis, Sacramento, CA, 95817, USA., Borowsky AD; Department of Pathology and Laboratory Medicine, School of Medicine, University of California Davis, Sacramento, CA, 95817, USA., Ferrara KW; Department of Radiology, Stanford University, 3165 Porter Dr, Palo Alto, CA, 94305, USA. kwferrar@stanford.edu.

Publikováno v: Scientific reports [Sci Rep] 2021 Jan 13; Vol. 11 (1), pp. 927. Date of Electronic Publication: 2021 Jan 13.

Low-frequency ultrasound-mediated cytokine transfection enhances T cell recruitment at local and distant tumor sites.

Autor: Ilovitsh T; Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305.; Department of Radiology, Stanford University, Stanford, CA 94305.; Department of Biomedical Engineering, University of California, Davis, CA 95616., Feng Y; Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305.; Department of Radiology, Stanford University, Stanford, CA 94305.; Department of Biomedical Engineering, Xi'an Jiaotong University, Xi'an 710049, People's Republic of China., Foiret J; Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305.; Department of Radiology, Stanford University, Stanford, CA 94305., Kheirolomoom A; Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305.; Department of Radiology, Stanford University, Stanford, CA 94305.; Department of Biomedical Engineering, University of California, Davis, CA 95616., Zhang H; Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305.; Department of Radiology, Stanford University, Stanford, CA 94305.; Department of Biomedical Engineering, University of California, Davis, CA 95616., Ingham ES; Department of Biomedical Engineering, University of California, Davis, CA 95616., Ilovitsh A; Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305.; Department of Radiology, Stanford University, Stanford, CA 94305.; Department of Biomedical Engineering, University of California, Davis, CA 95616., Tumbale SK; Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305.; Department of Radiology, Stanford University, Stanford, CA 94305., Fite BZ; Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305.; Department of Radiology, Stanford University, Stanford, CA 94305., Wu B; Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305.; Department of Radiology, Stanford University, Stanford, CA 94305., Raie MN; Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305.; Department of Radiology, Stanford University, Stanford, CA 94305., Zhang N; Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305.; Department of Radiology, Stanford University, Stanford, CA 94305., Kare AJ; Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305.; Department of Radiology, Stanford University, Stanford, CA 94305.; Department of Bioengineering, Stanford University, Stanford, CA 94305., Chavez M; Department of Bioengineering, Stanford University, Stanford, CA 94305., Qi LS; Department of Bioengineering, Stanford University, Stanford, CA 94305., Pelled G; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048.; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048., Gazit D; Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA 90048.; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048., Vermesh O; Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305.; Department of Radiology, Stanford University, Stanford, CA 94305., Steinberg I; Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305.; Department of Radiology, Stanford University, Stanford, CA 94305., Gambhir SS; Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305.; Department of Radiology, Stanford University, Stanford, CA 94305., Ferrara KW; Molecular Imaging Program at Stanford, Stanford University, Stanford, CA 94305; kwferrar@stanford.edu.; Department of Radiology, Stanford University, Stanford, CA 94305.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jun 09; Vol. 117 (23), pp. 12674-12685. Date of Electronic Publication: 2020 May 19.

Tumor-specific delivery of gemcitabine with activatable liposomes.

Autor: Tucci ST; University of California, Davis, Department of Biomedical Engineering, Davis, CA 95616, USA., Kheirolomoom A; University of California, Davis, Department of Biomedical Engineering, Davis, CA 95616, USA; Stanford University, Department of Radiology, 3165 Porter Drive, Palo Alto, CA 94304, USA., Ingham ES; University of California, Davis, Department of Biomedical Engineering, Davis, CA 95616, USA., Mahakian LM; University of California, Davis, Department of Biomedical Engineering, Davis, CA 95616, USA., Tam SM; University of California, Davis, Department of Biomedical Engineering, Davis, CA 95616, USA., Foiret J; Stanford University, Department of Radiology, 3165 Porter Drive, Palo Alto, CA 94304, USA., Hubbard NE; University of California, Davis, Center for Comparative Medicine, Davis, CA 95616, USA., Borowsky AD; University of California, Davis, Center for Comparative Medicine, Davis, CA 95616, USA., Baikoghli M; University of California, Davis, Department of Molecular and Cellular Biology, Davis, CA 95616, USA., Cheng RH; University of California, Davis, Department of Molecular and Cellular Biology, Davis, CA 95616, USA., Ferrara KW; Stanford University, Department of Radiology, 3165 Porter Drive, Palo Alto, CA 94304, USA. Electronic address: kwferrar@stanford.edu.

Publikováno v: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2019 Sep 10; Vol. 309, pp. 277-288. Date of Electronic Publication: 2019 Jul 10.

Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis.

Autor: Sundstrøm T; Kristian Gerhard Jebsen Brain Tumour Research Centre, Department of Biomedicine, University of Bergen, Jonas Lies vei 91, 5009, Bergen, Norway.; Department of Clinical Medicine, University of Bergen, Haukelandsveien 22, 5021, Bergen, Norway.; Department of Neurosurgery, Haukeland University Hospital, Haukelandsveien 22, 5021, Bergen, Norway., Prestegarden L; Kristian Gerhard Jebsen Brain Tumour Research Centre, Department of Biomedicine, University of Bergen, Jonas Lies vei 91, 5009, Bergen, Norway.; Department of Clinical Medicine, University of Bergen, Haukelandsveien 22, 5021, Bergen, Norway.; Department of Dermatology, Haukeland University Hospital, Haukelandsveien 22, 5021, Bergen, Norway., Azuaje F; NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84 Val Fleuri, 1526, Luxembourg, Luxembourg.; Present address: Proteome and Genome Research Unit, Department of Oncology, Luxembourg Institute of Health, 1A-B, rue Thomas Edison, L-1445, Strassen, Luxembourg, Luxembourg., Aasen SN; Kristian Gerhard Jebsen Brain Tumour Research Centre, Department of Biomedicine, University of Bergen, Jonas Lies vei 91, 5009, Bergen, Norway.; Department of Oncology and Medical Physics, Haukeland University Hospital, Haukelandsveien 22, 5021, Bergen, Norway., Røsland GV; Department of Biomedicine, University of Bergen, Jonas Lies vei 91, 5009, Bergen, Norway., Varughese JK; Kristian Gerhard Jebsen Brain Tumour Research Centre, Department of Biomedicine, University of Bergen, Jonas Lies vei 91, 5009, Bergen, Norway., Bahador M; Kristian Gerhard Jebsen Brain Tumour Research Centre, Department of Biomedicine, University of Bergen, Jonas Lies vei 91, 5009, Bergen, Norway., Bernatz S; Edinger-Institute (Neurological Institute), Goethe-University Medical School, Heinrich-Hoffmann-Strasse 7, 60528, Frankfurt am Main, Germany., Braun Y; Edinger-Institute (Neurological Institute), Goethe-University Medical School, Heinrich-Hoffmann-Strasse 7, 60528, Frankfurt am Main, Germany., Harter PN; Edinger-Institute (Neurological Institute), Goethe-University Medical School, Heinrich-Hoffmann-Strasse 7, 60528, Frankfurt am Main, Germany., Skaftnesmo KO; Institute of Marine Research, Nordnesgaten 50, 5005, Bergen, Norway., Ingham ES; Department of Biomedical Engineering, University of California Davis, 451 East Health Sciences Drive, Davis, CA, 95616, USA., Mahakian LM; Department of Biomedical Engineering, University of California Davis, 451 East Health Sciences Drive, Davis, CA, 95616, USA., Tam S; Department of Biomedical Engineering, University of California Davis, 451 East Health Sciences Drive, Davis, CA, 95616, USA., Tepper CG; Department of Biochemistry and Molecular Medicine, UC Davis Comprehensive Cancer Center, 4645 Second Avenue, Sacramento, CA, 95817, USA., Petersen K; Computational Biology Unit, Department of Informatics, University of Bergen, Thormøhlensgate 55, 5008, Bergen, Norway., Ferrara KW; Department of Biomedical Engineering, University of California Davis, 451 East Health Sciences Drive, Davis, CA, 95616, USA., Tronstad KJ; Department of Biomedicine, University of Bergen, Jonas Lies vei 91, 5009, Bergen, Norway., Lund-Johansen M; Department of Clinical Medicine, University of Bergen, Haukelandsveien 22, 5021, Bergen, Norway.; Department of Neurosurgery, Haukeland University Hospital, Haukelandsveien 22, 5021, Bergen, Norway., Beschorner R; Institute of Pathology and Neuropathology, Department of Neuropathology, University of Tuebingen, Tuebingen, Germany., Bjerkvig R; Kristian Gerhard Jebsen Brain Tumour Research Centre, Department of Biomedicine, University of Bergen, Jonas Lies vei 91, 5009, Bergen, Norway.; NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, 84 Val Fleuri, 1526, Luxembourg, Luxembourg., Thorsen F; Kristian Gerhard Jebsen Brain Tumour Research Centre, Department of Biomedicine, University of Bergen, Jonas Lies vei 91, 5009, Bergen, Norway. frits.thorsen@uib.no.; The Molecular Imaging Center, Department of Biomedicine, University of Bergen, Jonas Lies vei 91, 5009, Bergen, Norway. frits.thorsen@uib.no.

Publikováno v: Acta neuropathologica communications [Acta Neuropathol Commun] 2019 Apr 10; Vol. 7 (1), pp. 55. Date of Electronic Publication: 2019 Apr 10.