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Akademický článek

Effects of n-3 FA supplementation on the release of proresolving lipid mediators by blood mononuclear cells: the OmegAD study[S]

Autor: Xiuzhe Wang, Erik Hjorth, Inger Vedin, Maria Eriksdotter, Yvonne Freund-Levi, Lars-Olof Wahlund, Tommy Cederholm, Jan Palmblad, Marianne Schultzberg

Publikováno v: Journal of Lipid Research, Vol 56, Iss 3, Pp 674-681 (2015)

Specialized proresolving mediators (SPMs) induce resolution of inflammation. SPMs are derivatives of n-3 and n-6 PUFAs and may mediate their beneficial effects. It is unknown whether supplementation with PUFAs influences the production of SPMs. Alzhe

Externí odkaz: https://doaj.org/article/85d04510a8f441548ff1400100c09aa1

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Akademický článek

Reduced prostaglandin F2α release from blood mononuclear leukocytes after oral supplementation of ω3 fatty acids: the OmegAD study

Autor: Inger Vedin, Tommy Cederholm, Yvonne Freund-Levi, Hans Basun, Erik Hjorth, Gerd Faxén Irving, Maria Eriksdotter-Jönhagen, Marianne Schultzberg, Lars-Olof Wahlund, Jan Palmblad

Publikováno v: Journal of Lipid Research, Vol 51, Iss 5, Pp 1179-1185 (2010)

Omega-3 fatty acids, e.g., dokosahexaenoic acid (DHA) and eikosapentaenoic acid (EPA), ameliorate inflammatory reactions by various mechanisms, but the role of prostaglandins remains unclear. Our aim was to determine if dietary supplementation with a

Externí odkaz: https://doaj.org/article/e473dab620f946ad89e24671c779fe2e

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Akademický článek

Effects of DHA-rich n-3 fatty acid supplementation on gene expression in blood mononuclear leukocytes: the OmegAD study.

Autor: Inger Vedin, Tommy Cederholm, Yvonne Freund-Levi, Hans Basun, Anita Garlind, Gerd Faxén Irving, Maria Eriksdotter-Jönhagen, Lars-Olof Wahlund, Ingrid Dahlman, Jan Palmblad

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e35425 (2012)

Dietary fish oil, rich in n-3 fatty acids (n-3 FAs), e.g. docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), regulate inflammatory reactions by various mechanisms, e.g. gene activation. However, the effects of long-term treatment with DHA an

Externí odkaz: https://doaj.org/article/e8cc7e3d02cf4df1a63691b804dc504c

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Does Fatty Acid Composition in Subcutaneous Adipose Tissue Differ between Patients with Alzheimer’s Disease and Cohabiting Proxies?

Autor: Maria Eriksdotter, Farshad Falahati, Tommy Cederholm, Marianne Schultzberg, Hans Basun, Jan Palmblad, Yvonne Freund-Levi, Inger Vedin, Gerd Faxén-Irving, Erik Hjorth, Lars-Olof Wahlund

Publikováno v: Journal of Alzheimer's Disease. 61:515-519

Low tissue levels of the major marine ω3 fatty acids (FAs) DHA and EPA are found in Alzheimer's disease (AD). We investigated if healthy proxies to AD patients have higher levels of these ω3 FAs. We observed lower levels of EPA and DHA in subcutane

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb75212cb181d63ea47cf3a64eb4fae
https://doi.org/10.3233/jad-170359

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Effects of n-3 FA supplementation on the release of proresolving lipid mediators by blood mononuclear cells: the OmegAD study[S]

Autor: Maria Eriksdotter, Jan Palmblad, Yvonne Freund-Levi, Inger Vedin, Xiuzhe Wang, Tommy Cederholm, Marianne Schultzberg, Erik Hjorth, Lars-Olof Wahlund

Publikováno v: Journal of Lipid Research, Vol 56, Iss 3, Pp 674-681 (2015)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e1153098510c9d14c97bdb31670792b
http://www.sciencedirect.com/science/article/pii/S0022227520355954

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X-linked thrombocytopenia with thalassemia displays bone marrow reticulin fibrosis and enhanced angiogenesis: Comparisons with primary myelofibrosis

Autor: Eva Zetterberg, Inger Vedin, Victoria Hahn-Strömberg, Maria Åström, Jan Palmblad, Mats Merup

Publikováno v: American Journal of Hematology. 90:E44-E48

X-linked thrombocytopenia with thalassemia (XLTT) is caused by the mutation 216R > Q in exon 4 of the GATA1 gene. Male hemizygous patients display macrothrombocytopenia, splenomegaly, and a β-th ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4adfe1743617c4fb2d6dbe5089f74448
https://doi.org/10.1002/ajh.23907

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Effect of FCGR polymorphism on the occurrence of late-onset neutropenia and flare-free survival in rheumatic patients treated with rituximab

Autor: Bengt Fadeel, Inger Vedin, Jan Palmblad, Hans Hägglund, Daniel Tesfa, Sofia Ajeganova, Anna Linda Zignego

Publikováno v: Arthritis Research & Therapy

Background: The causes and mechanisms of late-onset neutropenia (LON) following rituximab treatment in patients with rheumatic diseases are not known. In this study, we aimed to investigate the role of established Fc gamma receptor gene (FCGR) polymo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6762eb575a8774308e62232e1ec5479
https://doi.org/10.1186/s13075-017-1241-0

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DHA-rich n-3 fatty acid supplementation decreases DNA methylation in blood leukocytes: the OmegAD study

Autor: Maria Eriksdotter, Jan Palmblad, Erik Hjorth, Gerd Faxén Irving, Tommy Cederholm, Marianne Schultzberg, Lars-Olof Wahlund, Yvonne Freund Levi, Inger Vedin, Mohsen Karimi, Hans Basun

Publikováno v: The American journal of clinical nutrition. 106(4)

Background: Dietary fish oils, rich in long-chain n-3 (ω-3) fatty acids (FAs) [e.g., docosahexaenoic acid (DHA, 22:6n-3) and eicosapentaenoic acid (EPA, 20:5n-3)], modulate inflammatory reactions through various mechanisms, including gene expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d20618230e5cfe95311e1b3b642bb9
https://pubmed.ncbi.nlm.nih.gov/28855224

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Transfer of omega-3 fatty acids across the blood-brain barrier after dietary supplementation with a docosahexaenoic acid-rich omega-3 fatty acid preparation in patients with Alzheimer's disease: the OmegAD study

Autor: Inger Vedin, Hans Basun, Norman Salem, Y Freund Levi, Tommy Cederholm, Maria Eriksdotter, Erik Hjorth, Marianne Schultzberg, G Faxén Irving, Jan Palmblad, L-O Wahlund, Bengt Vessby

Publikováno v: Journal of Internal Medicine. 275:428-436

Little is known about the transfer of essential fatty acids (FAs) across the human blood-brain barrier (BBB) in adulthood. In this study, we investigated whether oral supplementation with omega-3 (n-3) FAs would change the FA profile of the cerebrosp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58bb2739a2f23ea6c35da0c34a04aada
https://doi.org/10.1111/joim.12166

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Simple advice on lifestyle habits and long-term changes in biomarkers of inflammation and vascular adhesion in healthy middle-aged men

Autor: M.-L. Hellénius, M Heimbürger, Tommy Cederholm, Peter Stenvinkel, Inger Vedin, Jan Palmblad, Per Sjögren

Publikováno v: European Journal of Clinical Nutrition. 64:1450-1456

Lifestyle habits, vascular function and inflammation are components in the development of cardiovascular disease (CVD). We investigated whether simple advice on dietary and exercise habits given (at a single time point) to hypercholesterolemic men af

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bdf7f8861ec6bc09a8792bd218331c6
https://doi.org/10.1038/ejcn.2010.182

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