Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Inger Helene Madshus"'
Autor:
Juliana Bentes Hughes, Marianne Skeie Rødland, Max Hasmann, Inger Helene Madshus, Espen Stang
Publikováno v:
Pharmaceuticals, Vol 5, Iss 7, Pp 674-689 (2012)
ErbB2 is an important oncogenic protein involved in carcinogenesis of, among others, breast, gastric, and ovarian carcinoma. Over-expression of ErbB2 is found in almost 20% of breast cancers, and this results in proliferative and anti-apoptotic signa
Externí odkaz:
https://doaj.org/article/2402d2be1fae4e4eae3203bea07191ec
Autor:
Inger Helene Madshus, Espen Stang, Camilla Haslekås, Marianne Skeie Rødland, Kamilla Breen, Nina Marie Pedersen
Overexpression of the epidermal growth factor receptor (EGFR), ErbB2, and ErbB3 promotes growth and antiapoptotic signaling. Overexpression of ErbB2 in breast cancer is associated with poor clinical outcome, and ways of down-regulating ErbB2 are impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617d5c6b51194a2a74672c243123e69d
https://doi.org/10.1158/1541-7786.c.6542235.v1
https://doi.org/10.1158/1541-7786.c.6542235.v1
ErbB2, a member of the epidermal growth factor receptor family, is overexpressed in a number of human cancers. In contrast to the epidermal growth factor receptor, ErbB2 is normally endocytosis resistant. However, ErbB2 can be down-regulated by inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35fc4890cb4759dfe32f7e3e24ae7d87
https://doi.org/10.1158/1541-7786.c.6541519
https://doi.org/10.1158/1541-7786.c.6541519
Autor:
Inger Helene Madshus, Espen Stang, Camilla Haslekås, Marianne Skeie Rødland, Kamilla Breen, Nina Marie Pedersen
Supplementary Data from Expression of Epidermal Growth Factor Receptor or ErbB3 Facilitates Geldanamycin-Induced Down-Regulation of ErbB2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e81af25c9e067034b4c38452aac506c
https://doi.org/10.1158/1541-7786.22519014
https://doi.org/10.1158/1541-7786.22519014
Supplementary Figures S1-S8 from Geldanamycin-Induced Down-Regulation of ErbB2 from the Plasma Membrane Is Clathrin Dependent but Proteasomal Activity Independent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7131f8696c32ddd0dd3aaab985cdfc
https://doi.org/10.1158/1541-7786.22516873
https://doi.org/10.1158/1541-7786.22516873
Autor:
Nina Marie Pedersen, Kamilla Breen, Inger Helene Madshus, Espen Stang, Sissel Beate Rønning, Malgorzata Magdalena Sak, Vibeke Bertelsen
Publikováno v:
Carcinogenesis. 33:1031-1039
The oncoprotein ErbB3 is overexpressed in several human cancers, for example in pancreatic adenocarcinoma and in ovarian cancers, and ErbB3-containing heterodimers have been demonstrated to be potent signaling units in carcinogenesis. This especially
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27677256c97437f03050351a8917a5e7
https://doi.org/10.1093/carcin/bgs128
https://doi.org/10.1093/carcin/bgs128
Publikováno v:
Journal of Immunotherapy. 34:550-555
The epidermal growth factor receptor (EGFR) is overexpressed in several epithelial tumors such as breast, ovarian, and colon cancers. Nimotuzumab and Cetuximab are antibodies that inhibit ligand binding upon interaction with the EGFR, thereby indirec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74bdc27945a1d8ce6c97b7cfc0261623
https://doi.org/10.1097/cji.0b013e31822a5ca6
https://doi.org/10.1097/cji.0b013e31822a5ca6
Publikováno v:
Experimental Cell Research. 317:1804-1816
CIN85 has been demonstrated to interact with a number of proteins involved in endocytosis and intracellular sorting. However, the exact functional role of CIN85 in endocytosis remains unclear. We have investigated whether CIN85 plays a role in EGF-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185a0290ffca62a122fcf54e73889f03
https://doi.org/10.1016/j.yexcr.2011.05.016
https://doi.org/10.1016/j.yexcr.2011.05.016
Autor:
Lene E. Johannessen, Marianne Skeie Rødland, Kamilla Breen, Inger Helene Madshus, Espen Stang, Malgorzata Magdalena Sak, Linton M. Traub, Vibeke Bertelsen
Publikováno v:
Traffic. 12:507-520
The roles of EGF receptor (EGFR) kinase activity and ubiquitination in EGFR endocytosis have been controversial. The adaptor protein and ubiquitin ligase Cbl has reportedly been required. Consistently, we now report that siRNA-mediated knock-down of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1691939e2a93f4485f484190a9edef43
https://doi.org/10.1111/j.1600-0854.2011.01162.x
https://doi.org/10.1111/j.1600-0854.2011.01162.x
Autor:
Inger Helene Madshus, Espen Stang
Publikováno v:
Journal of Cell Science. 122:3433-3439
The epidermal growth factor receptor (EGFR; also known as ErbB1) is one of four related receptor tyrosine kinases. These receptors (EGFR, ErbB2, ErbB3 and ErbB4) are frequently overexpressed in cancer and such overexpression is associated with poor c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acd371205421a9e2411a6a82e982e6b9
https://doi.org/10.1242/jcs.050260
https://doi.org/10.1242/jcs.050260