Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Inger Hedlund"'
Publikováno v:
Acta Pharmacologica et Toxicologica. 40:337-346
The use of lidocaine as an oral antiarrhythmic drug is limited by its rapid disposition in the liver. In accordance with this we found that the drug was completely extracted during one passage through the perfused rat liver. The drug binds to rat liv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f877e5a6aca2456f7f33ee7fe04493d5
https://doi.org/10.1111/j.1600-0773.1977.tb02086.x
https://doi.org/10.1111/j.1600-0773.1977.tb02086.x
Publikováno v:
Acta Pharmacologica et Toxicologica. 41:39-48
When the local anaesthetic drug lidocaine is added to liver microsomes biphasic type I spectral change titration curves can be observed. A high-affinity and a low-affinity phase is observed. In the present study we have found that microsomes from fem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d34a60e901044275576fa1baf5272a9
https://doi.org/10.1111/j.1600-0773.1977.tb02121.x
https://doi.org/10.1111/j.1600-0773.1977.tb02121.x
Addition of lidocaine to liver microsomes results in biphasic type I spectral titration curves. A high-affinity and a low-affinity binding phase exist. In this study we have found that microsomes from female rats have a marked high affinity phase, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9388c38bb0433c7f95ceb2595045c28b
https://doi.org/10.1016/b978-0-08-021523-5.50073-0
https://doi.org/10.1016/b978-0-08-021523-5.50073-0
