Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Inger, Øynebråten"'
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-12 (2024)
Abstract The cytokine IL-12p70 is crucial for T helper 1 (Th1) polarization and the generation of type 1 immunity required to fight cancer and pathogens. Therefore, strategies to optimize the production of IL-12p70 by human dendritic cells (DCs) may
Externí odkaz:
https://doaj.org/article/11169d30924549af9a3b3e8a61c709a5
Autor:
Christian Winther Wold, Panagiotis F. Christopoulos, Maykel A. Arias, Deborah Elikplim Dzovor, Inger Øynebråten, Alexandre Corthay, Kari Tvete Inngjerdingen
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Fungal polysaccharides can exert immunomodulating activity by triggering pattern recognition receptors (PRRs) on innate immune cells such as macrophages. Here, we evaluate six polysaccharides isolated from the medicinal fungus Inonotus obliq
Externí odkaz:
https://doaj.org/article/2c0b065120dd49d3a363ac344ab27225
Autor:
Adrian Eek Mariampillai, Sissel Hauge, Inger Øynebråten, Gro Elise Rødland, Alexandre Corthay, Randi G. Syljuåsen
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Recent studies suggest that inhibition of the ATR kinase can potentiate radiation-induced antitumor immune responses, but the extent and mechanisms of such responses in human cancers remain scarcely understood. We aimed to assess whether the ATR inhi
Externí odkaz:
https://doaj.org/article/7fea646455fc4b5b8ee5d1fb69887e1b
Autor:
Astri Frafjord, Linn Buer, Clara Hammarström, Henrik Aamodt, Per Reidar Woldbæk, Odd Terje Brustugun, Åslaug Helland, Inger Øynebråten, Alexandre Corthay
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Tumor-specific T helper (Th) cells have a central role in the immune response against cancer. However, there exist distinct Th cell subsets with very different and antagonizing properties. Some Th subsets such as Th1 protect against cancer, while oth
Externí odkaz:
https://doaj.org/article/2b51742e4f6f426790d9afff1e6a5702
Autor:
Algirdas Grevys, Jeannette Nilsen, Kine M. K. Sand, Muluneh B. Daba, Inger Øynebråten, Malin Bern, Martin B. McAdam, Stian Foss, Tilman Schlothauer, Terje E. Michaelsen, Gregory J. Christianson, Derry C. Roopenian, Richard S. Blumberg, Inger Sandlie, Jan Terje Andersen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
The development of IgG and albumin-based therapeutics with increased half-lives needs more efficient screening procedures. Here the authors report a human endothelial cell-based recycling assay enabling screening of IgG and albumin variants without c
Externí odkaz:
https://doaj.org/article/99bc76e2016a473a870d99a7c561cd47
Autor:
Branislava Stankovic, Heidi Anine Korsmo Bjørhovde, Renate Skarshaug, Henrik Aamodt, Astri Frafjord, Elisabeth Müller, Clara Hammarström, Kahsai Beraki, Espen S. Bækkevold, Per Reidar Woldbæk, Åslaug Helland, Odd Terje Brustugun, Inger Øynebråten, Alexandre Corthay
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death in the world. Immunological analysis of the tumor microenvironment (immunoscore) shows great promise for improved prognosis and prediction of response to immunotherapy. H
Externí odkaz:
https://doaj.org/article/23f4e3550d51486b9033e97b07bfce84
Autor:
Elisabeth Müller, Martin Speth, Panagiotis F. Christopoulos, Anna Lunde, Ajna Avdagic, Inger Øynebråten, Alexandre Corthay
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Triggering or enhancing antitumor activity of tumor-associated macrophages is an attractive strategy for cancer treatment. We have previously shown that the cytokine interferon-γ (IFN-γ), a type II IFN, could synergize with toll-like receptor (TLR)
Externí odkaz:
https://doaj.org/article/fce3ae6c41d14a9ca4215b91e582e8c5
IL-12p70 is crucial for T helper 1 polarization and the generation of type 1 immunity that is required to fight cancer and intracellular pathogens. Therefore, strategies to optimize the production of IL-12p70 by dendritic cells (DCs) may significantl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::784a8381a875b59c4dc7a0733ba79e64
https://doi.org/10.1101/2022.10.03.510527
https://doi.org/10.1101/2022.10.03.510527
Generation and Functional In Vitro Analysis of Semliki Forest Virus Vectors Encoding TNF-α and IFN-γ
Autor:
Baiba Kurena, Elisabeth Müller, Panagiotis F. Christopoulos, Ingvild Bjellmo Johnsen, Branislava Stankovic, Inger Øynebråten, Alexandre Corthay, Anna Zajakina
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Cytokine gene delivery by viral vectors is a promising novel strategy for cancer immunotherapy. Semliki Forest virus (SFV) has many advantages as a delivery vector, including the ability to (i) induce p53-independent killing of tumor cells via apopto
Externí odkaz:
https://doaj.org/article/f48e56ba43c4412fa9d2c0e29a2fec30
Autor:
Elisabeth Müller, Panagiotis F. Christopoulos, Sanjib Halder, Anna Lunde, Kahsai Beraki, Martin Speth, Inger Øynebråten, Alexandre Corthay
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Tumor-associated macrophages may either promote or suppress tumor growth depending on their activation status. Interferon-γ (IFN-γ) has been identified as a key factor for inducing tumoricidal M1 phenotype in macrophages. However, it remains unclea
Externí odkaz:
https://doaj.org/article/f4537a9af3614cf5a8c5dd66a2591084