Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Ingemar, Qvarfordt"'
Autor:
Magnus Paulsson, Eduardo I. Cardenas, Karlhans F. Che, Bettina Brundin, Margaretha Smith, Ingemar Qvarfordt, Anders Lindén
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundBacterial infection causes accumulation of neutrophils that release antimicrobial proteins including heparin-binding protein (HBP). In human airways, this neutrophil accumulation can be re-capitulated via intrabronchial exposure to lipopoly
Externí odkaz:
https://doaj.org/article/d1708e069af64652964cb9f0315168e5
Autor:
Magnus Paulsson, Louise Thelaus, Kristian Riesbeck, Ingemar Qvarfordt, Margaretha E. Smith, Anders Lindén, Adam Linder
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-4 (2021)
Abstract Objectives Ventilator-associated pneumonia (VAP) is difficult to diagnose using clinical criteria and no biomarkers have yet been proved to be sufficiently accurate. The use of the neutrophil-derived Heparin-binding protein (HBP) as a biomar
Externí odkaz:
https://doaj.org/article/c2021c547827471a9a7f5be4ce300a09
Autor:
Marit Stockfelt, Karin Christenson, Anders Andersson, Lena Björkman, Médea Padra, Bettina Brundin, Koustav Ganguly, Helga Asgeirsdottir, Sara Lindén, Ingemar Qvarfordt, Johan Bylund, Anders Lindén
Publikováno v:
Journal of Innate Immunity, Pp 1-10 (2020)
There is incomplete mechanistic understanding of the mobilization of neutrophils in the systemic and local compartment in smokers with chronic obstructive pulmonary disease (COPD). In this pilot study, we characterized how the adhesion molecules CD11
Externí odkaz:
https://doaj.org/article/d59aaacc23e44e66b11390798994fd31
Autor:
Magnus Paulsson, Karlhans F. Che, Jonas Ahl, Johan Tham, Linda Sandblad, Margaretha E. Smith, Ingemar Qvarfordt, Yu-Ching Su, Anders Lindén, Kristian Riesbeck
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Pathogens causing pneumonia utilize the complement regulator vitronectin to evade complement-mediated killing. Although vitronectin is associated with several chronic lung diseases, the role of bronchoalveolar vitronectin in pneumonia has not been st
Externí odkaz:
https://doaj.org/article/0033cbeded09497b8469640ea452603c
Autor:
Maria, Hess-Wargbaner, Gunnar, Jacobsson, Denny, Björk, Annika, Edholm, Ingemar, Qvarfordt, Pär-Daniel, Sundvall, Peter, Ulleryd, Christina, Åhrén
Publikováno v:
Lakartidningen. 119
Optimizing antibiotic use to control the spread of antimicrobial resistance is a global health priority. The Swedish strategic programme against antibiotic resistance (Strama) has for many years supported the rational use of antibiotics. A key elemen
Autor:
Anders Andersson, Sara K. Lindén, Ingemar Qvarfordt, Anders Lindén, Bettina Brundin, Theodore J. Standiford, Michael W. Newstead, Helga Asgeirsdottir, Médea Padra, Karlhans Fru Che, Melissa Kovach
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Chronic obstructive pulmonary disease (COPD) is a progressive inflammatory lung disease with high morbidity and mortality. The IL-36 family are proinflammatory cytokines that are known to shape innate immune responses, including those critical to bac
Autor:
Michael Landreh, Ákos Végvári, Peter Bergman, Birgitta Agerberth, Anders Lindén, Astrid Gräslund, Melanie D. Balhuizen, Cecilia Wallin, Margaretha E. Smith, Maarten Coorens, Edwin J.A. Veldhuizen, Salma Al-Adwani, Ingemar Qvarfordt
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, 10(1). NLM (Medline)
Scientific Reports
Scientific Reports, 10(1). NLM (Medline)
Scientific Reports
Arginine residues of the antimicrobial peptide LL-37 can be citrullinated by peptidyl arginine deiminases, which reduce the positive charge of the peptide. Notably, citrullinated LL-37 has not yet been detected in human samples. In addition, function
Autor:
Nikolaos, Pournaras, Anders, Andersson, Melissa A, Kovach, Médea, Padra, Karlhans F, Che, Bettina, Brundin, Shigemi, Yoshihara, Steven, Bozinovski, Sara K, Lindén, Per-Anders, Jansson, Magnus C, Sköld, Ingemar, Qvarfordt, Anders, Lindén
Publikováno v:
International journal of chronic obstructive pulmonary disease. 17
Type 2 diabetes mellitus (T2DM) and metabolic syndrome (MetS) are common comorbidities in chronic obstructive pulmonary disease (COPD), but the underlying pathogenic mechanisms are poorly understood. Given that these morbidities all display increased
Autor:
Médea, Padra, John, Benktander, János T, Padra, Anders, Andersson, Bettina, Brundin, Sara, Tengvall, Karin, Christenson, Ingemar, Qvarfordt, Robert, Gad, Magnus, Paulsson, Nikolaos, Pournaras, Anders, Lindén, Sara K, Lindén
Publikováno v:
American journal of respiratory cell and molecular biology. 65(6)
Chronic obstructive pulmonary disease (COPD) is associated with colonization by bacterial pathogens and repeated airway infections, leading to exacerbations and impaired lung function. The highly glycosylated mucins in the mucus lining the airways ar
Autor:
Margaretha E Smith, Steven Bozinovski, Carina Malmhäll, Margareta Sjöstrand, Pernilla Glader, Per Venge, Pieter S Hiemstra, Gary P Anderson, Anders Lindén, Ingemar Qvarfordt
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e75032 (2013)
We tested the hypothesis that activation of the innate immune response induces an imbalance in the proteolytic homeostasis in the peripheral airways of healthy subjects, towards excess serine or gelatinase proteinase activity. During bronchoscopy, 18
Externí odkaz:
https://doaj.org/article/097a50799582498f901ee40875231daf