Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ingeborg Pohl"'
Autor:
Ingeborg Pohl, Horst Spielmann, Andrea Seiler, Susanne Bremer, K. Becker, Elke Genschow, Nicole Clemann, Gabriele Scholz
Publikováno v:
Alternatives to Laboratory Animals. 32:209-244
A detailed report is presented on the performance of the embryonic stem cell test (EST) in a European Centre for the Validation of Alternative Methods (ECVAM)-sponsored formal validation study on three in vitro tests for embryotoxicity. Twenty coded
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc72b467e9d1886a98149c5ef21dfdb
https://doi.org/10.1177/026119290403200305
https://doi.org/10.1177/026119290403200305
Autor:
Ingeborg Pohl
Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfängen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen für die historische wie auch die disziplingesch
Publikováno v:
Toxicology in Vitro. 15:447-453
To offer a sensitive and predictive in vitro method to assess germ cell mutagenicity, we established primordial germ (PG) cell-derived permanent female and male embryonic germ (EG) cell lines of the mouse (strain BALB/cJ). The differences in developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a69d0a0ae9a6255a9b8d45a5c160e9d
https://doi.org/10.1016/s0887-2333(01)00050-9
https://doi.org/10.1016/s0887-2333(01)00050-9
Autor:
Hans Raabe, Jacqueline Southee, Suzanne Bremer, Martin Paparella, Ingeborg Pohl, Gabriele Scholz, Horst Spielmann, Elke Genschow
Publikováno v:
Toxicology in Vitro. 13:675-681
Pluripotent embryonic stem cells (ES cells) of the mouse (cell-line D3) can be maintained in the undifferentiated state in the presence of LIF (Leukaemia Inhibitory Factor). Upon withdrawal of LIF, these cells differentiate into various cell types un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8c4a619e7eff1b135a3790dc955fbc
https://doi.org/10.1016/s0887-2333(99)00046-6
https://doi.org/10.1016/s0887-2333(99)00046-6
Publikováno v:
Toxicology in Vitro. 7:551-556
Mouse embryonic stem (ES) cell line D3 was used to establish conditions for a reproducible differentiation of ES cells in culture. ES cells can be maintained in an undifferentiated state by cultivation on a feeder layer of embryonic fibroblasts. ES c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8be83d3880e66476525f0932675b6b5
https://doi.org/10.1016/0887-2333(93)90064-c
https://doi.org/10.1016/0887-2333(93)90064-c
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 8(4)
The earliest identified state of a specific cell in mammalian embryonic development is the embryonic stem cell (ES cell). The murine ES cell line D3 was used to establish conditions that allow a reproducible differentiation of ES cells in culture. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb73c4dcead5db7b4528d8d34b31afa
https://pubmed.ncbi.nlm.nih.gov/20692966
https://pubmed.ncbi.nlm.nih.gov/20692966
Autor:
Andrea, Seiler, Anke, Visan, Ingeborg, Pohl, Elke, Genschow, Roland, Buesen, Horst, Spielmann
Publikováno v:
ALTEX. 19
Blastocyst-derived pluripotent embryonic stem (ES) cells of the mouse can be induced to differentiate in culture into a variety of cell types, including cardiac muscle cells. In the embryonic stem cell test (EST) the capacity of ES cells of the mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5dc6b955f0c8135f9941f1af8355e98b
https://pubmed.ncbi.nlm.nih.gov/12096331
https://pubmed.ncbi.nlm.nih.gov/12096331
Autor:
Gabriele, Scholz, Ingeborg, Pohl, Andrea, Seiler, Susanne, Bremer, Nigel A., Brown, Aldert H., Piersma, Hermann Georg, Holzhütter, Horst, Spielmann
Publikováno v:
ALTEX. 15(1)
The results of the experimental prevalidation of three in vitro embryotoxicity tests in an ECVAM study are reported: the rat whole embryo culture assay (WEC), the micromass assay (MM) and the embryonic stem cell test (EST). Three test chemicals assig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77ac5c20777ae87bd4378795877cd9c5
https://pubmed.ncbi.nlm.nih.gov/11208261
https://pubmed.ncbi.nlm.nih.gov/11208261
Autor:
Marc Fiszman, Austin Smith, Anna M. Wobus, Ian Chambers, Elke Genschow, Hans R. Schöler, Eckhard Wolf, Maurizio Pesce, Nicholas Hole, Ingeborg Pohl, Craig Stracey, Pascale Chenevier, Svetlana Vassilieva, Horst Spielmann, Christian Dani, Martina Klemm, Eugen Kolossov, Hitoshi Niwa, Jürgen Rohwedel, Tom Burdon, Wilhelm Bloch, G. J. Ji, Konstantinos Anastassiadis, Juergen Hescheler, David I. Gottlieb, James E. Huettner, Katja Prelle, Heinrich Sauer, Kenneth R. Boheler, H.-W. Denker, Jacques Samarut, Bertrand Pain, Bernd K. Fleischmann, Ivan Vassiliev, Klaus Addicks, Maria Wartenberg, Gabriele Scholz, Kaomei Guan
Publikováno v:
Cells Tissues Organs. 165:256-256
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b323724f6ff88249e67d6585783c9cdb
https://doi.org/10.1159/000016690
https://doi.org/10.1159/000016690