Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ingeborg Dhaese"'
Autor:
Peter Brouckaert, Ingeborg Dhaese, Robrecht Thoonen, Anne Vral, Romain Lefebvre, Sarah Cosyns, Emmanuel S. Buys
Publikováno v:
Neurogastroenterology & Motility. 25:e339-e352
Background Soluble guanylate cyclase (sGC) is the principal target of nitric oxide (NO) to control gastrointestinal motility. The consequence on nitrergic signaling and gut motility of inducing a heme-free status of sGC, as induced by oxidative stres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15c8988386412e1835a67daba2a8335
https://doi.org/10.1111/nmo.12120
https://doi.org/10.1111/nmo.12120
Autor:
Peter Brouckaert, Gwen Vanneste, Emmanuel S. Buys, Ingeborg Dhaese, Romain Lefebvre, Patrick Sips
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 379:473-487
Nitric oxide (NO) activates soluble guanylate cyclase (sGC) to produce guanosine-3',5'-cyclic-monophosphate (cGMP). The aim of this study was to investigate the nitrergic regulation of jejunal motility in sGCalpha(1) knockout (KO) mice. Functional re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340cbb93034d8d355f9694e079050e5a
https://doi.org/10.1007/s00210-008-0380-x
https://doi.org/10.1007/s00210-008-0380-x
Autor:
Ingeborg Dhaese, Peter Brouckaert, Emmanuel S. Buys, Gwen Vanneste, Patrick Sips, Romain Lefebvre
Publikováno v:
The Journal of Physiology. 584:907-920
The principal target of the relaxant neurotransmitter nitric oxide (NO) is soluble guanylate cyclase (sGC). As the α1β1-isoform of sGC is the predominant one in the gastrointestinal tract, the aim of this study was to investigate the role of sGC in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b50fc3f2cbb84f94e48d043ec6c8514
https://doi.org/10.1113/jphysiol.2007.140608
https://doi.org/10.1113/jphysiol.2007.140608
Autor:
Ingeborg Dhaese, I. Van Colen, Ezio Fulcheri, Simone Ferrero, Romain Lefebvre, Giovanni Camerini, Valentino Remorgida
Publikováno v:
Neurogastroenterology & Motility.
Background The 5-HT4 receptor agonist prucalopride enhances large intestinal contractility by facilitating acetylcholine release through activation of 5-HT4 receptors on cholinergic nerves and is effective in patients with constipation. Patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7ca33043b470a1d34e5caff689dcc3
https://doi.org/10.1111/j.1365-2982.2009.01438.x
https://doi.org/10.1111/j.1365-2982.2009.01438.x
Publikováno v:
European journal of pharmacology. 628(1-3)
Hydrogen sulfide (H(2)S) has been suggested as a gaseous neuromodulator in mammals. The aim of this study was to examine the influence of H(2)S on contractility in mouse distal colon. The effect of sodium hydrogen sulfide (NaHS; H(2)S donor) on prost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc4c74e56cf1bfd67ee653639cf1686
https://pubmed.ncbi.nlm.nih.gov/19919833
https://pubmed.ncbi.nlm.nih.gov/19919833
Autor:
Ingeborg Dhaese, Romain Lefebvre
Publikováno v:
European journal of pharmacology. 606(1-3)
The relaxant effect of hydrogen sulfide (H(2)S) in the vascular tree is well established but its influence and mechanism of action in gastrointestinal smooth muscle was hardly investigated. The influence of H(2)S on contractility in mouse gastric fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b637ac64643a34bc50d671f26dddf8a9
https://pubmed.ncbi.nlm.nih.gov/19374871
https://pubmed.ncbi.nlm.nih.gov/19374871
Autor:
Gwen, Vanneste, Ingeborg, Dhaese, Patrick, Sips, Emmanuel, Buys, Peter, Brouckaert, Romain A, Lefebvre
Publikováno v:
The Journal of physiology. 584(Pt 3)
The principal target of the relaxant neurotransmitter nitric oxide (NO) is soluble guanylate cyclase (sGC). As the alpha(1)beta(1)-isoform of sGC is the predominant one in the gastrointestinal tract, the aim of this study was to investigate the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cecc8d3bdf89c48b98846eba05994289
https://pubmed.ncbi.nlm.nih.gov/17717014
https://pubmed.ncbi.nlm.nih.gov/17717014
Autor:
Romain Lefebvre, Peter Brouckaert, Ingeborg Dhaese, Patrice Sips, Emmanuel S. Buys, Gwen Vanneste
Publikováno v:
BMC Pharmacology. 5
Nitric oxide (NO) is the most important relaxant neurotransmitter in the gastric fundus. The principal target of NO is soluble guanylate cyclase (sGC). As the α1β1 isoform is most abundant in the gastrointestinal tract, the aim of this study was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac92ffb82c77eb35a50ff7a3500893bc
https://doi.org/10.1186/1471-2210-5-s1-p56
https://doi.org/10.1186/1471-2210-5-s1-p56
Publikováno v:
BMC Pharmacology. 7(Suppl 1):P15
Nitric oxide (NO) is the most important relaxant neurotransmitter in the stomach. The principal target of NO is soluble guanylate cyclase (sGC), of which two physiologically prevailing isoforms exist, namely α1β1 and α2β1. The aim of this study w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4f8a3a1cebf40d7e48eb9ca758895dd
Autor:
Ingeborg Dhaese, Emmanuel S. Buys, Peter Brouckaert, Patrick Sips, Romain Lefebvre, Gwen Vanneste
Publikováno v:
BMC Pharmacology. 5(Suppl 1):P14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456b9d951dea2e34d4266484a5b38ae2