Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Inge van Rooy"'
Autor:
Jos J.M. Drabbels, Erik H. Rozemuller, Robert Welleweerd, Geert W. Haasnoot, Guro M. Johnsen, Inge van Rooy, Anne Cathrine Staff, Michael Eikmans, Frans H.J. Claas, Nienke Westerink
Publikováno v:
Hla
HLA: Immune Response Genetics, 96(2), 179-185. WILEY
HLA: Immune Response Genetics, 96(2), 179-185. WILEY
Polymorphic sites in the HLA-G gene may influence expression and function of the protein. Knowledge of the association between high-resolution HLA-G alleles and 3-prime untranslated (3 ' UTR) haplotypes is useful for studies on the role of HLA-G in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc3e722976b3232153dbe533dc6fe552
https://doi.org/10.1111/tan.13909
https://doi.org/10.1111/tan.13909
Autor:
Mihaela Skobe, Catharina de Lange Davies, Inge van Rooy, Sjoerd Hak, Jun Tang, Yiming Zhao, Edward A. Fisher, Zahi A. Fayad, Willem J. M. Mulder, Celso de Mello Donegá, Francois Fay, Andries Meijerink, Aurelian Radu
Publikováno v:
ACS nano, 7(11), 10362-10370. American Chemical Society
In the current study we show the dissociation and tumor accumulation dynamics of dual labeled near infrared (NIR) quantum dot core self-assembled lipidic nanoparticles (SALNPs) in a mouse model upon intravenous administration. Using advanced in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::585933f89fd32d386c8619b2c59503e5
https://doi.org/10.1021/nn404782p
https://doi.org/10.1021/nn404782p
Publikováno v:
European Journal of Pharmaceutical Sciences. 45:330-335
In our previous study, phage display selections were performed by in situ perfusion of a random peptide library through a mouse brain. This yielded two peptides (GLA and GYR) that showed significant binding to human brain endothelial cells (hCMEC/D3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2cb49340b5d027a02f9982e711c941
https://doi.org/10.1016/j.ejps.2011.11.015
https://doi.org/10.1016/j.ejps.2011.11.015
Autor:
Raymond M. Schiffelers, Heike Dinter-Heidorn, Shin-Ying Wu, Wim E. Hennink, Enrico Mastrobattista, Inge van Rooy, Gert Storm
Publikováno v:
International Journal of Pharmaceutics. 416:448-452
Neurotensin-degrading enzyme (NTDE) inhibitors hold great potential for treating psychotic disorders. However, brain uptake of such compounds in vivo is generally low due to the presence of the blood–brain barrier. In this study, liposomal formulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50be24249a94b8f41fb1b075ecc0d95
https://doi.org/10.1016/j.ijpharm.2011.01.017
https://doi.org/10.1016/j.ijpharm.2011.01.017
Publikováno v:
Nanomedicine. 2:169-181
At present, there are no intravenously administered nucleic acid-based therapeutics that have been approved for human use. This reflects the difficulties in applying nucleic acid-based drugs: they are nuclease sensitive and have difficulties in reach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a87149bc25885f2a84819690e7e60f
https://doi.org/10.2217/17435889.2.2.169
https://doi.org/10.2217/17435889.2.2.169
Autor:
Erik H. Rozemuller, Remco Malestein, Robert Welleweerd, Maarten T. Penning, Hanneke W. M. van Deutekom, Raul Kooter, Inge van Rooy, Job Geerligs, Frans-Paul Ruzius, Michelle van Heck, Pieter Meulenberg
Publikováno v:
Human Immunology. 78:174
Aim HLA genes are the most polymorphic genes in the human genome. The encoded HLA molecules play a pivotal role in generating a target dependent immune response. Several HLA molecules are even associated with a specific disease or drug responsiveness
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1c77d029cab4c1d52384960acfb3268
https://doi.org/10.1016/j.humimm.2017.06.220
https://doi.org/10.1016/j.humimm.2017.06.220
Autor:
Inge van Rooy, Omid C. Farokhzad, Aneta J. Mieszawska, Canturk Ozcan, David P. Cormode, Artiom Petrov, Zahi A. Fayad, YongTae Kim, Matthew P. Labarre, Bram Priem, Robert Langer, Willem J. M. Mulder, Anita Gianella
Publikováno v:
Bioconjugate chemistry, 24(9), 1429-1434. American Chemical Society
For advanced treatment of diseases such as cancer, multi component, multi functional nanoparticles hold great promise. In the current study we report the synthesis of a complex nanoparticle (NP) system with dual drug loading as well as diagnostic pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1757eba4fd004b1b7be3cc6b81f67dd7
https://pubmed.ncbi.nlm.nih.gov/23957728
https://pubmed.ncbi.nlm.nih.gov/23957728
Autor:
Maarten T. Penning, Claudia Rebel, Michelle van Heck, Inge van Rooy, Nienke Westerink, Erik H. Rozemuller
Publikováno v:
Human Immunology. 77:95
Aim Strong association of HLA molecules with autoimmune and inflammatory diseases have been identified, strengthening the value of HLA genetic screening for diagnostic purposes. There’s a strong association between Ankylosing Spondylitis (AS) and H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c88963b7716649515ed180a6744090f5
https://doi.org/10.1016/j.humimm.2016.07.145
https://doi.org/10.1016/j.humimm.2016.07.145
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 150(1)
In many different studies nanocarriers modified with targeting ligands have been used to target to the brain. Many ligands have been successful, but it is difficult to compare results from different studies to determine which targeting ligand is the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4a19ccb9670a41054e8730d0270738
https://pubmed.ncbi.nlm.nih.gov/21087646
https://pubmed.ncbi.nlm.nih.gov/21087646
Publikováno v:
International journal of pharmaceutics. 331(2)
Small interfering RNA (siRNA) molecules are the functional mediators of a post-transcriptional gene silencing process known as RNA interference (RNAi). The silencing of genes involved in diseases, using siRNA, is considered a very promising therapeut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5bc0df399c87e79f0d48f280b5cb95
https://pubmed.ncbi.nlm.nih.gov/17187949
https://pubmed.ncbi.nlm.nih.gov/17187949