Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Inge de Reus"'
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Akademický článek
Peptide-mediated ‘miniprep’ isolation of extracellular vesicles is suitable for high-throughput proteomics
Autor: Jaco C. Knol, Inge de Reus, Tim Schelfhorst, Robin Beekhof, Meike de Wit, Sander R. Piersma, Thang V. Pham, Egbert F. Smit, Henk M.W. Verheul, Connie R. Jiménez
Publikováno v: EuPA Open Proteomics, Vol 11, Iss C, Pp 11-15 (2016)
Extracellular vesicles (EVs) are cell-secreted membrane vesicles enclosed by a lipid bilayer derived from endosomes or from the plasma membrane. Since EVs are released into body fluids, and their cargo includes tissue-specific and disease-related mol
Externí odkaz: https://doaj.org/article/bb4a8f3db5ab4f28ad192f7a0c7580f1
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2
Effects of Cancer Presence and Therapy on the Platelet Proteome
Autor: Henk J. Broxterman, Henk L. Dekker, Henk M.W. Verheul, Mirjam G.A. oude Egbrink, Connie R. Jimenez, Jaco C. Knol, Thang V. Pham, Maudy Walraven, Siamack Sabrkhany, Sander R. Piersma, Inge de Reus, Arjan W. Griffioen
Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, 22
International Journal of Molecular Sciences, 22(15):8236. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, Vol 22, Iss 8236, p 8236 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 15; Pages: 8236
Walraven, M, Sabrkhany, S, Knol, J C, Dekker, H, de Reus, I, Piersma, S R, Pham, T V, Griffioen, A W, Broxterman, H J, Oude Egbrink, M, Verheul, H M W & Jimenez, C R 2021, ' Effects of Cancer Presence and Therapy on the Platelet Proteome ', International Journal of Molecular Sciences, vol. 22, no. 15, 8236 . https://doi.org/10.3390/ijms22158236
International journal of molecular sciences, 22(15):8236. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, 22, 15
Contains fulltext : 238212.pdf (Publisher’s version ) (Open Access) Platelets are involved in tumor angiogenesis and cancer progression. Previous studies indicated that cancer could affect platelet content. In the current study, we investigated whe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb6dbcb1574f3512b03e398858f1a79
http://europepmc.org/articles/PMC8347210
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3
Proteome analysis of non-small cell lung cancer cell line secretomes and patient sputum reveals biofluid biomarker candidates for cisplatin response prediction
Autor: Remco Nagel, Thang V. Pham, Connie R. Jimenez, Franziska Böttger, Egbert F. Smit, Tieneke B M Schaaij-Visser, Ruud H. Brakenhoff, Sander R. Piersma, Inge de Reus, Erik Thunnissen
Publikováno v: Böttger, F, Schaaij-Visser, T B, de Reus, I, Piersma, S R, Pham, T V, Nagel, R, Brakenhoff, R H, Thunnissen, E, Smit, E F & Jimenez, C R 2019, ' Proteome analysis of non-small cell lung cancer cell line secretomes and patient sputum reveals biofluid biomarker candidates for cisplatin response prediction ', Journal of Proteomics, vol. 196, pp. 106-119 . https://doi.org/10.1016/j.jprot.2019.01.018
Journal of Proteomics, 196, 106-119. Elsevier
Molecular markers are urgently needed to select non-small cell lung cancer (NSCLC) patients most likely to benefit from platinum-based chemotherapies. Of particular interest are proteins that can be found in biofluids like sputum for non-invasive det
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075b66444116b293a3b6e923fea8e836
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85061200372&origin=inward
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4
Feasibility of label-free phosphoproteomics and application to base-line signaling of colorectal cancer cell lines
Autor: Sander R. Piersma, Thang V. Pham, Connie R. Jimenez, Bharath K. Sampadi, Jaco C. Knol, Henk M.W. Verheul, Inge de Reus, Mariette Labots, Yasushi Ishihama
Publikováno v: Journal of Proteomics, 127, 247-258. Elsevier
Piersma, S R, Knol, J C, de Reus, I, Labots, M, Sampadi, B K, Pham, T V, Ishihama, Y, Verheul, H M W & Jimenez, C R 2015, ' Feasibility of label-free phosphoproteomics and application to base-line signaling of colorectal cancer cell lines ', Journal of Proteomics, vol. 127, pp. 247-258 . https://doi.org/10.1016/j.jprot.2015.03.019
Robust phosphopeptide enrichment methods with minimal fractionation are required to profile signaling network analysis in cancer cell lines and tissues. We assessed performance of single-shot LC-MS/MS label-free phosphoproteomics using TiOx-based pho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edae3cd790e6561a4f2e4e0701fedeac
https://research.vumc.nl/en/publications/0f889d35-5e79-4d83-bd39-faadaa4949ee
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5
Whole gel processing procedure for GeLC-MS/MS based proteomics
Autor: Meike de Wit, Connie R. Jimenez, Sander R. Piersma, Jaco C. Knol, Marc O. Warmoes, Inge de Reus
Publikováno v: Piersma, S R, Warmoes, M O, de Wit, M, de Reus, I, Knol, J C & Jimenez, C R 2013, ' Whole gel processing procedure for GeLC-MS/MS based proteomics ', Proteome Science, vol. 11, 17 . https://doi.org/10.1186/1477-5956-11-17
Proteome Science, 11:17. BioMed Central
Proteome Science
Background SDS-PAGE followed by in-gel digestion (IGD) is a popular workflow in mass spectrometry-based proteomics. In GeLC-MS/MS, a protein lysate of a biological sample is separated by SDS-PAGE and each gel lane is sliced in 5–20 slices which, af
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::742b7848369f7dc32f8771ccf37b4971
https://research.vumc.nl/en/publications/e9ebbe62-8654-4d6f-a93e-abc31b47aee4
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7
Abstract 572: Proteomics analysis of the effect of fluorouracil (5FU) and 5FU/leucovorin (LV) on colorectal cancer (CRC) in patients
Autor: Sander R. Piersma, Erik Meijer, Inge de Reus, Kees Smid, Godefridus J. Peters, Thang V. Pham, Connie R. Jimenez
Publikováno v: Cancer Research. 75:572-572
Background: 5FU is widely used and inhibits thymidylate synthase (TS); LV given in combination with 5FU enhances TS inhibition. TS levels and inhibition are associated with survival in advanced disease. The large variation in response between patient
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9b10abd170de24c93a36dcc3b00f8f37
https://doi.org/10.1158/1538-7445.am2015-572
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Abstract 2007: Phosphoproteomics scaled-down to tumor biopsies for future TKI treatment selection
Autor: Gerrit A. Meijer, Mariette Labots, Sander R. Piersma, Jaco C. Knol, Henk M.W. Verheul, Robin Beekhof, Thang V. Pham, Johannes C. van der Mijn, Connie R. Jimenez, Richard R. de Haas, Nicole C.T. van Grieken, Inge de Reus
Publikováno v: Cancer Research. 75:2007-2007
Introduction Mass spectrometry-based phosphoproteomics of cancer cell- and tissue lysates provides a unique approach to evaluate the cell signaling network, revealing information on aberrantly activated signaling pathways and potential drug targets.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b6cf69bd07443c970ea3223de1f34725
https://doi.org/10.1158/1538-7445.am2015-2007
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9
Abstract 2488: Novel candidate protein biomarkers for cisplatin response prediction in non-small cell lung cancer
Autor: Remco Nagel, Thang V. Pham, Connie R. Jimenez, Ruud H. Brakenhoff, Sander R. Piersma, Frederik B. Thunnissen, Inge de Reus, Tieneke B M Schaaij-Visser, Anton Berns, Egbert F. Smit
Publikováno v: Cancer Research. 73:2488-2488
The five-year survival rate for non-small cell lung cancer (NSCLC) is still less than twenty percent in part due to treatment failure and lack of biomarkers for personalized therapy. Most NSCLC patients are treated by chemotherapy and cisplatin is st
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c1c60a7b263f5a8a2ff0cac296e36e1b
https://doi.org/10.1158/1538-7445.am2013-2488
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