Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Inge W Nilsen"'
Publikováno v:
Marine Drugs, Vol 11, Iss 11, Pp 4279-4293 (2013)
The screening of extracts from marine organisms is a widely used strategy to discover new drug leads. A common problem in the screening process is the generation of false positive hits through unspecific effects from the complex chemical composition
Externí odkaz:
https://doaj.org/article/d29205b896b34901b6f23ab1c976bcfc
Autor:
Inge W Nilsen, Kersti Øverbø, Linda Jensen Havdalen, Morten Elde, Dag Rune Gjellesvik, Olav Lanes
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10295 (2010)
BACKGROUND: We have previously isolated a thermolabile nuclease specific for double-stranded DNA from industrial processing water of Northern shrimps (Pandalus borealis) and developed an application of the enzyme in removal of contaminating DNA in PC
Externí odkaz:
https://doaj.org/article/525c647dc26041eea40a8b3fb69ceaa5
Publikováno v:
Fish & Shellfish Immunology. 44:66-78
Phagocyte recognition of lipopolysaccharide (LPS) is an early key event for triggering the host innate immune response necessary for clearance of invading bacteria. The ability of fishes to recognise LPS has been questioned as contradictory results h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4b3e3f75d6903cd5b197e531cd13c5
https://doi.org/10.1016/j.fsi.2015.01.018
https://doi.org/10.1016/j.fsi.2015.01.018
Publikováno v:
Marine Drugs, Vol 11, Iss 11, Pp 4279-4293 (2013)
Marine Drugs
Marine Drugs; Volume 11; Issue 11; Pages: 4279-4293
Marine Drugs
Marine Drugs; Volume 11; Issue 11; Pages: 4279-4293
The screening of extracts from marine organisms is a widely used strategy to discover new drug leads. A common problem in the screening process is the generation of false positive hits through unspecific effects from the complex chemical composition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a0a7f3fd259926cb2e24a3778c4b14a
http://www.mdpi.com/1660-3397/11/11/4279
http://www.mdpi.com/1660-3397/11/11/4279
Autor:
Kathrine Ryvold Bakkemo, David M. Irwin, Helene Mikkelsen, Marit Seppola, Bjørnar Myrnes, Ronny Helland, Inge W. Nilsen
Publikováno v:
Scientific Reports
Previous analyses of the Atlantic cod genome showed unique combinations of lacking and expanded number of genes for the immune system. The present study examined lysozyme activity, lysozyme gene distribution and expression in cod. Enzymatic assays em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece0fe9a823986c96ea04224ed8ffb1f
https://hdl.handle.net/10037/9573
https://hdl.handle.net/10037/9573
Autor:
J.M. Van Herreweghe, Geert Baggerman, Chris W. Michiels, Kristof Vanoirbeek, Lien Callewaert, Inge W. Nilsen, Paul Declerck, Bjørnar Myrnes, Lise Vanderkelen
Publikováno v:
Cellular and Molecular Life Sciences. 68:1053-1064
Lysozymes are antibacterial effectors of the innate immune system in animals that hydrolyze peptidoglycan. Bacteria have evolved protective mechanisms that contribute to lysozyme tolerance such as the production of lysozyme inhibitors, but only inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7754bfa907869c67383293acda62ec
https://doi.org/10.1007/s00018-010-0507-3
https://doi.org/10.1007/s00018-010-0507-3
Publikováno v:
Journal of Molecular Modeling. 14:777-788
It is known that bacteria contain inhibitors of lysozyme activity. The recently discovered Escherichia coli inhibitor of vertebrate lysozyme (Ivy) and its potential interactions with several goose-type (g-type) lysozymes from fish were studied using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::150c180a9dffe1e4f137cce3f9e3eef6
https://doi.org/10.1007/s00894-008-0317-9
https://doi.org/10.1007/s00894-008-0317-9
Publikováno v:
Cellular and Molecular Life Sciences. 64:2841-2847
The Atlantic salmon (Salmo salar) goose-type lysozyme gene was isolated and revealed alternative splicing within exon 2 affecting the signal peptide-encoding region. The lysozyme was produced in Escherichia coli, and the recombinant enzyme showed a h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2917bfd55ce39a5b49734bfdf97ae5c
https://doi.org/10.1007/s00018-007-7372-8
https://doi.org/10.1007/s00018-007-7372-8
Autor:
Bjørnar Myrnes, Inge W. Nilsen
Publikováno v:
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 144:403-407
Glutathione S-transferase from the digestive gland of the cold-adapted marine bivalve Icelandic scallop was purified to apparent homogeneity by single GSTrap chromatography. The enzyme appeared to be a homodimer with subunit M(r) 22,000 having an opt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45acdebc22c821215345396245677a04
https://doi.org/10.1016/j.cbpc.2006.11.011
https://doi.org/10.1016/j.cbpc.2006.11.011
Publikováno v:
Cellular and Molecular Life Sciences (CMLS). 60:2210-2218
Genome clones and expressed sequence tags (ESTs) from the ascidian Ciona intestinalis and from the larvacean Oikopleura dioica were analysed for the presence of lysozyme-encoding genes. Two genes were found to potentially code for goose-type lysozyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f4ab5401e1c3f68fbcbd0819f739ab
https://doi.org/10.1007/s00018-003-3252-z
https://doi.org/10.1007/s00018-003-3252-z