Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Inge S Zuhorn"'
Autor:
Changsen Leng, Arend W Overeem, Fernando Cartón-Garcia, Qinghong Li, Karin Klappe, Jeroen Kuipers, Yingying Cui, Inge S Zuhorn, Diego Arango, Sven C D van IJzendoorn
Publikováno v:
PLoS Biology, Vol 17, Iss 11, p e3000531 (2019)
Recycling endosomes regulate plasma membrane recycling. Recently, recycling endosome-associated proteins have been implicated in the positioning and orientation of the mitotic spindle and cytokinesis. Loss of MYO5B, encoding the recycling endosome-as
Externí odkaz:
https://doaj.org/article/1b4a66d3c270420c97d3c8248a67f1c8
Autor:
Bhagyashree S. Joshi, Inge S. Zuhorn
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 102134- (2023)
Summary: Here, we present a protocol using genetic engineering techniques to prepare small extracellular vesicles (sEVs) enriched in the chaperone protein DNAJB6. We describe steps to prepare cell lines overexpressing DNAJB6, followed by the isolatio
Externí odkaz:
https://doaj.org/article/ac884dc55b954567aea88275495d0288
Publikováno v:
Acta Biomaterialia, 155, 507-520. ELSEVIER SCI LTD
Targeted drug delivery requires -among others- specific interaction of nanocarriers with cell surface receptors enabling efficient internalization into the targeted cells. Thus, identification of receptors allowing efficient nanocarrier uptake is ess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8155efbffe01ddc987177557bf02fbe4
https://doi.org/10.1016/j.actbio.2022.11.010
https://doi.org/10.1016/j.actbio.2022.11.010
Autor:
Juan Villar-Vesga, Julián Henao-Restrepo, Daniëlle C. Voshart, David Aguillon, Andrés Villegas, Diana Castaño, Julián D. Arias-Londoño, Inge S. Zuhorn, Laís Ribovski, Lara Barazzuol, Gloria P. Cardona-Gómez, Rafael Posada-Duque
Publikováno v:
Frontiers in Aging Neuroscience, Vol 12 (2020)
Evidence suggests that extracellular vesicles (EVs) act as mediators and biomarkers of neurodegenerative diseases. Two distinct forms of Alzheimer disease (AD) are known: a late-onset sporadic form (SAD) and an early-onset familial form (FAD). Recent
Externí odkaz:
https://doaj.org/article/b8a7c53b691342daba3e611386f296c6
Autor:
Huaiying Zhang, Damla Keskin, Willy H. de Haan-Visser, Guangyue Zu, Patrick van Rijn, Inge S. Zuhorn
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1964 (2021)
Gene therapy is a promising treatment for hereditary diseases, as well as acquired genetic diseases, including cancer. Facing the complicated physiological and pathological environment in vivo, developing efficient non-viral gene vectors is needed fo
Externí odkaz:
https://doaj.org/article/d7ab6458ceae48b59d21b301d3a768ab
Autor:
Natalia Ortí-Casañ, Yingying Wu, Petrus J. W. Naudé, Peter P. De Deyn, Inge S. Zuhorn, Ulrich L. M. Eisel
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia. Accumulating experimental evidence shows the important linkage between tumor necrosis factor-α (TNF) and AD, but the exact role of TNF in A
Externí odkaz:
https://doaj.org/article/b25979966f3a451cbf0782759e37c72d
Autor:
Laís Ribovski, Yong Liu, Reinier Bron, Jeroen Bussmann, Inge S. Zuhorn, Winant L van Os, Xiaobo Tian, Alexander Kros, Huaiying Zhang, Guangyue Zu
Publikováno v:
Biomaterials Science, 9(21), 7092-7103. ROYAL SOC CHEMISTRY
Biomaterials Science. Royal Society of Chemistry (RSC)
Biomaterials Science
Biomaterials Science. Royal Society of Chemistry (RSC)
Biomaterials Science
Glioblastoma (GBM) is a devastating primary brain tumor resistant to conventional therapies. A major obstacle to GBM treatment is the blood-brain barrier (BBB), or blood-glioma barrier, which prevents the transport of systemically administered (chemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44a04b768994742fb7363d93d6d244cb
https://doi.org/10.1039/d0bm01536a
https://doi.org/10.1039/d0bm01536a
Publikováno v:
Pharmaceutics, 14(11):2485. MDPI AG
Pharmaceutics; Volume 14; Issue 11; Pages: 2485
Pharmaceutics; Volume 14; Issue 11; Pages: 2485
Cell-derived extracellular vesicles (EVs) are effectors of cell-to-cell communication that are in the spotlight as promising candidates for in vivo drug delivery because of their ability to enter cells and deliver cargo. For example, proteins of inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62fd113e962c5b4bbec9a03186a38a43
https://research.rug.nl/en/publications/82d774ee-eb28-4f17-bfb9-aedca6d6299a
https://research.rug.nl/en/publications/82d774ee-eb28-4f17-bfb9-aedca6d6299a
Autor:
Natalia Ortí-Casañ, Inge S. Zuhorn, Petrus J. W. Naudé, Peter P. De Deyn, Pauline E. M. van Schaik, Harald Wajant, Ulrich L. M. Eisel
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 119(37). NATL ACAD SCIENCES
Tumor necrosis factor-α (TNF-α) is a pleiotropic, proinflammatory cytokine related to different neurodegenerative diseases, including Alzheimer’s disease (AD). Although the linkage between increased TNF-α levels and AD is widely recognized, TNF-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d246ac3edd86a222892bc0fa3ed33af
https://research.rug.nl/en/publications/ce6884f7-27c9-4de4-9608-dc561848e0b3
https://research.rug.nl/en/publications/ce6884f7-27c9-4de4-9608-dc561848e0b3
Autor:
Yuanke Liang, Daniëlle Voshart, Judith T. M. L. Paridaen, Nynke Oosterhof, Dong Liang, Arun Thiruvalluvan, Inge S. Zuhorn, Wilfred F. A. den Dunnen, Guojun Zhang, Haoyu Lin, Lara Barazzuol, Frank A. E. Kruyt
Publikováno v:
Cellular and molecular life sciences, 79(8):398. SPRINGER BASEL AG
Glioblastoma (GBM), a highly malignant and lethal brain tumor, is characterized by diffuse invasion into the brain and chemo-radiotherapy resistance resulting in poor prognosis. In this study, we examined the involvement of the cell adhesion molecule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1511793e511b6bf67dae4af297904edf
https://research.rug.nl/en/publications/89fb25ea-fe83-48c2-8de8-dc8b68a05225
https://research.rug.nl/en/publications/89fb25ea-fe83-48c2-8de8-dc8b68a05225
