Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Inge M. N. Wortel"'
Autor:
Kalijn F. Bol, Gerty Schreibelt, Martine Bloemendal, Wouter W. van Willigen, Simone Hins-de Bree, Anna L. de Goede, Annemiek J. de Boer, Kevin J. H. Bos, Tjitske Duiveman-de Boer, Michel A. M. Olde Nordkamp, Tom G. M. van Oorschot, Carlijn J. Popelier, Jeanne M. Pots, Nicole M. Scharenborg, Mandy W. M. M. van de Rakt, Valeska de Ruiter, Wilmy S. van Meeteren, Michelle M. van Rossum, Sandra J. Croockewit, Bouke J. Koeneman, Jeroen H. A. Creemers, Inge M. N. Wortel, Caroline Angerer, Mareke Brüning, Katja Petry, Andrzej Dzionek, Astrid A. van der Veldt, Dirk J. van Grünhagen, Johanna E. M. Werner, Johannes J. Bonenkamp, John B. A. G. Haanen, Marye J. Boers-Sonderen, Rutger H. T. Koornstra, Martijn F. Boomsma, Erik H. J. Aarntzen, Martin Gotthardt, James Nagarajah, Theo J. M. de Witte, Carl G. Figdor, Johannes H. W. de Wilt, Johannes Textor, Jan Willem B. de Groot, Winald R. Gerritsen, I. Jolanda M. de Vries
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Autologous natural dendritic cells (nDCs) treatment can induce tumor-specific immune responses and clinical responses in cancer patients. In this phase III clinical trial (NCT02993315), 148 patients with resected stage IIIB/C melanoma were r
Externí odkaz:
https://doaj.org/article/245269452ff04a81b46a9a6846fb6516
Publikováno v:
Cells, Vol 9, Iss 3, p 690 (2020)
Our immune system can destroy most cells in our body, an ability that needs to be tightly controlled. To prevent autoimmunity, the thymic medulla exposes developing T cells to normal “self” peptides and prevents any responders from entering the b
Externí odkaz:
https://doaj.org/article/08a9170f8f104805b9e61fcb2e07e1b1
Autor:
Inge M N Wortel, Johannes Textor
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 2, p e1010918 (2023)
Two decades of in vivo imaging have revealed how diverse T-cell motion patterns can be. Such recordings have sparked the notion of search "strategies": T cells may have evolved ways to search for antigen efficiently depending on the task at hand. Mat
Externí odkaz:
https://doaj.org/article/25d5ae36eef34bfab63dccdbee7329c3
Publikováno v:
PLoS Pathogens, Vol 18, Iss 12, p e1011028 (2022)
Listeria monocytogenes (Lm) is a food-borne pathogen that causes severe bacterial gastroenteritis, with high rates of hospitalization and mortality. Lm is ubiquitous in soil, water and livestock, and can survive and proliferate at low temperatures. F
Externí odkaz:
https://doaj.org/article/90bb744437804f11a6cfe40faca5dafb
Autor:
Kim Monkhorst, Johannes Textor, Michel M van den Heuvel, Katrien Grünberg, Jeroen H A Creemers, Carl G Figdor, I Jolanda M de Vries, Lieke L van der Woude, Mark A J Gorris, Inge M N Wortel, Kiek Verrijp, Berber Piet, Willemijn S M E Theelen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 10 (2022)
Background Immunotherapy is currently part of the standard of care for patients with advanced-stage non-small cell lung cancer (NSCLC). However, many patients do not respond to this treatment, therefore combination strategies are being explored to in
Externí odkaz:
https://doaj.org/article/663cd6a76af94357ad61372c788c6ddb
Autor:
Leonie van Steijn, Inge M N Wortel, Clément Sire, Loïc Dupré, Guy Theraulaz, Roeland M H Merks
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 2, p e1009156 (2022)
Lymphocytes have been described to perform different motility patterns such as Brownian random walks, persistent random walks, and Lévy walks. Depending on the conditions, such as confinement or the distribution of target cells, either Brownian or L
Externí odkaz:
https://doaj.org/article/d287ed4aded643598f220f86d6e0e51e
We recently conducted an exploratory analysis of murine T cell receptor (TCR) repertoire data (biorxiv doi:10.1101/2022.11.23.517563).Specifically, we analyzed the complement-determining region 3 (CDR3) of the TCRβ chain from naïve CD4+T cell popul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8df714bf24b53357b493c459d77e2d32
Autor:
Johannes Textor, Franka Buytenhuijs, Dakota Rogers, Ève Mallet Gauthier, Shabaz Sultan, Inge M. N. Wortel, Kathrin Kalies, Anke Fähnrich, René Pagel, Heather J. Melichar, Jürgen Westermann, Judith N. Mandl
SummaryThe T cell receptor (TCR) determines the specificity and affinity for both foreign and self-peptides presented by MHC. It is established that self-pMHC reactivity impacts T cell function, but it has been challenging to identify TCR sequence fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edc9027d2582ce5a6cf550c31dc65956
https://doi.org/10.1101/2022.11.23.517563
https://doi.org/10.1101/2022.11.23.517563
Listeria monocytogenes (Lm) is a food-borne pathogen that causes severe bacterial gastroenteritis, with high rates of hospitalization and mortality. Lm is ubiquitous in soil, water and livestock, and can survive and proliferate at low temperatures. F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebc263987a80c64267225f9312b3180f
https://doi.org/10.1101/2022.07.21.500464
https://doi.org/10.1101/2022.07.21.500464
Autor:
Lieke L van der Woude, Mark A J Gorris, Inge M N Wortel, Jeroen H A Creemers, Kiek Verrijp, Kim Monkhorst, Katrien Grünberg, Michel M van den Heuvel, Johannes Textor, Carl G Figdor, Berber Piet, Willemijn S M E Theelen, I Jolanda M de Vries
Publikováno v:
Journal for Immunotherapy of Cancer, 10
Journal for Immunotherapy of Cancer, 10, 10
Journal for Immunotherapy of Cancer, 10, 10
BackgroundImmunotherapy is currently part of the standard of care for patients with advanced-stage non-small cell lung cancer (NSCLC). However, many patients do not respond to this treatment, therefore combination strategies are being explored to inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f72befe4acddd9e0159627d71ac430c
http://hdl.handle.net/2066/283861
http://hdl.handle.net/2066/283861