Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Inge M. M. Lakeman"'
Autor:
Barbara Rentroia-Pacheco, Domenico Bellomo, Inge M. M. Lakeman, Marlies Wakkee, Loes M. Hollestein, David van Klaveren
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Nested case–control (NCC) designs are efficient for developing and validating prediction models that use expensive or difficult-to-obtain predictors, especially when the outcome is rare. Previous research has focused on how to d
Externí odkaz:
https://doaj.org/article/15095719da6b4ddaae30480a1597cc54
Autor:
Leila Dorling, Sara Carvalho, Jamie Allen, Michael T. Parsons, Cristina Fortuno, Anna González-Neira, Stephan M. Heijl, Muriel A. Adank, Thomas U. Ahearn, Irene L. Andrulis, Päivi Auvinen, Heiko Becher, Matthias W. Beckmann, Sabine Behrens, Marina Bermisheva, Natalia V. Bogdanova, Stig E. Bojesen, Manjeet K. Bolla, Michael Bremer, Ignacio Briceno, Nicola J. Camp, Archie Campbell, Jose E. Castelao, Jenny Chang-Claude, Stephen J. Chanock, Georgia Chenevix-Trench, NBCS Collaborators, J. Margriet Collée, Kamila Czene, Joe Dennis, Thilo Dörk, Mikael Eriksson, D. Gareth Evans, Peter A. Fasching, Jonine Figueroa, Henrik Flyger, Marike Gabrielson, Manuela Gago-Dominguez, Montserrat García-Closas, Graham G. Giles, Gord Glendon, Pascal Guénel, Melanie Gündert, Andreas Hadjisavvas, Eric Hahnen, Per Hall, Ute Hamann, Elaine F. Harkness, Mikael Hartman, Frans B. L. Hogervorst, Antoinette Hollestelle, Reiner Hoppe, Anthony Howell, kConFab Investigators, SGBCC Investigators, Anna Jakubowska, Audrey Jung, Elza Khusnutdinova, Sung-Won Kim, Yon-Dschun Ko, Vessela N. Kristensen, Inge M. M. Lakeman, Jingmei Li, Annika Lindblom, Maria A. Loizidou, Artitaya Lophatananon, Jan Lubiński, Craig Luccarini, Michael J. Madsen, Arto Mannermaa, Mehdi Manoochehri, Sara Margolin, Dimitrios Mavroudis, Roger L. Milne, Nur Aishah Mohd Taib, Kenneth Muir, Heli Nevanlinna, William G. Newman, Jan C. Oosterwijk, Sue K. Park, Paolo Peterlongo, Paolo Radice, Emmanouil Saloustros, Elinor J. Sawyer, Rita K. Schmutzler, Mitul Shah, Xueling Sim, Melissa C. Southey, Harald Surowy, Maija Suvanto, Ian Tomlinson, Diana Torres, Thérèse Truong, Christi J. van Asperen, Regina Waltes, Qin Wang, Xiaohong R. Yang, Paul D. P. Pharoah, Marjanka K. Schmidt, Javier Benitez, Bas Vroling, Alison M. Dunning, Soo Hwang Teo, Anders Kvist, Miguel de la Hoya, Peter Devilee, Amanda B. Spurdle, Maaike P. G. Vreeswijk, Douglas F. Easton
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-17 (2022)
Abstract Background Protein truncating variants in ATM, BRCA1, BRCA2, CHEK2, and PALB2 are associated with increased breast cancer risk, but risks associated with missense variants in these genes are uncertain. Methods We analyzed data on 59,639 brea
Externí odkaz:
https://doaj.org/article/45c3e08cffb0447d8b0bfc7a2f10352e
Autor:
Mar Rodríguez-Girondo, Inge M. M. Lakeman, André G. Uitterlinden, Andy C. H. Lee, Peter Devilee, Bruno H. Stricker, Antonis C. Antoniou, Jeroen van Rooij, Sara R.A. Wijnant, Marjanka K. Schmidt, Rikje Ruiter, Maryam Kavousi
Publikováno v:
Genetics in Medicine, 22(11), 1803-1811. NATURE PUBLISHING GROUP
Genetics in Medicine, 22(11), 1803-1811. Lippincott Williams & Wilkins
Genetics in Medicine
Genetics in Medicine, 22(11), 1803-1811. Lippincott Williams & Wilkins
Genetics in Medicine
Purpose We evaluated the performance of the recently extended Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm (BOADICEA version 5) in a Dutch prospective cohort, using a polygenic risk score (PRS) based on 313 breast
Autor:
Lambertus A. Kiemeney, Inge M. M. Lakeman, Mar Rodríguez-Girondo, Tara W J van der Grinten, Jennifer H. Barrett, Thomas P. Potjer, Mark M. Iles, Christi J. van Asperen, Nienke van der Stoep, Nelleke A. Gruis, Sander Bollen
Publikováno v:
Journal of Medical Genetics, 58(11), 760-766. BMJ PUBLISHING GROUP
Journal of Medical Genetics
Journal of Medical Genetics, 58, 760-766
Journal of Medical Genetics, 2021(58), 760-766. BMJ Publishing Group
Journal of Medical Genetics, 58, 11, pp. 760-766
Journal of Medical Genetics
Journal of Medical Genetics, 58, 760-766
Journal of Medical Genetics, 2021(58), 760-766. BMJ Publishing Group
Journal of Medical Genetics, 58, 11, pp. 760-766
BackgroundFamilial clustering of melanoma suggests a shared genetic predisposition among family members, but only 10%–40% of familial cases carry a pathogenic variant in a known high-risk melanoma susceptibility gene. We investigated whether a mela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ab7607027d0f8c06f5ea07758f8d20
https://jmg.bmj.com/content/jmedgenet/early/2020/09/28/jmedgenet-2020-107251.full.pdf
https://jmg.bmj.com/content/jmedgenet/early/2020/09/28/jmedgenet-2020-107251.full.pdf
Autor:
Douglas F. Easton, Manuela Gago-Dominguez, Marina Bermisheva, Marike Gabrielson, Michael J. Madsen, Antoinette Hollestelle, Joe Dennis, Roger L. Milne, Per Hall, Andreas Hadjisavvas, Muriel A. Adank, Melissa C. Southey, Anthony Howell, Qin Wang, Thilo Dörk, Elza Khusnutdinova, Nicola J. Camp, Miguel de la Hoya, Pascal Guénel, Archie Campbell, Gord Glendon, Javier Benitez, Sgbcc Investigators, Manjeet K. Bolla, Jonine D. Figueroa, Paolo Radice, Maaike P.G. Vreeswijk, William G. Newman, Soo Hwang Teo, Anna Jakubowska, Paul D.P. Pharoah, Sara Margolin, Thomas U. Ahearn, Mitul Shah, Eric Hahnen, Matthias W. Beckmann, Dimitrios Mavroudis, Elinor J. Sawyer, Paolo Peterlongo, Artitaya Lophatananon, Melanie Gündert, Maria A. Loizidou, Xueling Sim, Irene L. Andrulis, Ignacio Briceño, Mehdi Manoochehri, Rita K. Schmutzler, Maija Suvanto, Sara Carvalho, Amanda B. Spurdle, Georgia Chenevix-Trench, Marjanka K. Schmidt, Graham G. Giles, Peter A. Fasching, Inge M. M. Lakeman, Vessela N. Kristensen, Leila Dorling, Annika Lindblom, Harald Surowy, Jan C. Oosterwijk, Diana Torres, Nur Aishah Taib, Xiaohong R. Yang, D. Gareth Evans, Päivi Auvinen, Heli Nevanlinna, Sabine Behrens, Arto Mannermaa, Christi J. van Asperen, Anna González-Neira, Ian Tomlinson, Thérèse Truong, Heiko Becher, J. Margriet Collée, Jenny Chang-Claude, Mikael Hartman, Michael T. Parsons, Jamie Allen, Henrik Flyger, Sue K. Park, Craig Luccarini, Sung-Won Kim, Stephan M. Heijl, Montserrat Garcia-Closas, Cristina Fortuno, Jingmei Li, Peter Devilee, Yon-Dschun Ko, Reiner Hoppe, Stig E. Bojesen, Regina Waltes, Frans B. L. Hogervorst, Alison M. Dunning, Kenneth Muir, Mikael Eriksson, Bas Vroling, Jan Lubinski, Jose E. Castelao, Stephen J. Chanock, Natalia Bogdanova, Anders Kvist, Michael Bremer, Emmanouil Saloustros, Kamila Czene, kConFab Investigators, Elaine F. Harkness, Audrey Y. Jung, Ute Hamann
BACKGROUNDProtein truncating variants in ATM, BRCA1, BRCA2, CHEK2 and PALB2 are associated with increased breast cancer risk, but risks associated with missense variants in these genes are uncertain.METHODSCombining 59,639 breast cancer cases and 53,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a24075c2663579276f6ee62770dd244
https://doi.org/10.1101/2021.09.02.21262369
https://doi.org/10.1101/2021.09.02.21262369
Autor:
Mar Rodríguez-Girondo, Edith Olah, Andy C. H. Lee, Hanne Meijers-Heijboer, Christi J. van Asperen, Maaike P.G. Vreeswijk, Nicoline Hoogerbrugge, Peter Devilee, Caroline Seynaeve, Jan C. Oosterwijk, Florentine Hilbers, Inge M. M. Lakeman, Antoinette Hollestelle, Hans F. A. Vasen
Publikováno v:
Journal of Medical Genetics, 56(9), 581-589. Journal of Medical Genetics
Journal of Medical Genetics, 56, 9, pp. 581-589
Lakeman, I M M, Hilbers, F S, Rodríguez-Girondo, M, Lee, A, Vreeswijk, M P G, Hollestelle, A, Seynaeve, C, Meijers-Heijboer, H, Oosterwijk, J C, Hoogerbrugge, N, Olah, E, Vasen, H F A, van Asperen, C J & Devilee, P 2019, ' Addition of a 161-SNP polygenic risk score to family history-based risk prediction: Impact on clinical management in non-BRCA1/2 breast cancer families ', Journal of Medical Genetics, vol. 56, no. 9, pp. 581-589 . https://doi.org/10.1136/jmedgenet-2019-106072
Journal of Medical Genetics, 56(9), 581-589. BMJ Publishing Group
JOURNAL OF MEDICAL GENETICS, 56(9), 581-589. BMJ PUBLISHING GROUP
Journal of medical genetics, 56(9), 581-589. BMJ Publishing Group
Journal of Medical Genetics, 56, 581-589
Journal of Medical Genetics, 56, 9, pp. 581-589
Lakeman, I M M, Hilbers, F S, Rodríguez-Girondo, M, Lee, A, Vreeswijk, M P G, Hollestelle, A, Seynaeve, C, Meijers-Heijboer, H, Oosterwijk, J C, Hoogerbrugge, N, Olah, E, Vasen, H F A, van Asperen, C J & Devilee, P 2019, ' Addition of a 161-SNP polygenic risk score to family history-based risk prediction: Impact on clinical management in non-BRCA1/2 breast cancer families ', Journal of Medical Genetics, vol. 56, no. 9, pp. 581-589 . https://doi.org/10.1136/jmedgenet-2019-106072
Journal of Medical Genetics, 56(9), 581-589. BMJ Publishing Group
JOURNAL OF MEDICAL GENETICS, 56(9), 581-589. BMJ PUBLISHING GROUP
Journal of medical genetics, 56(9), 581-589. BMJ Publishing Group
Journal of Medical Genetics, 56, 581-589
BackgroundThe currently known breast cancer-associated single nucleotide polymorphisms (SNPs) are presently not used to guide clinical management. We explored whether a genetic test that incorporates a SNP-based polygenic risk score (PRS) is clinical
Autor:
Rita K. Schmutzler, Eric Hahnen, Anne Brédart, C. J. van Asperen, C. Ernst, Inge M. M. Lakeman, B. Blümcke, R. Remy, Peter Devilee, Kerstin Rhiem, J. Dick, Anja Tüchler, Dominique Stoppa-Lyonnet
Publikováno v:
Annals of Oncology. 32:S1104
Publikováno v:
Current Genetic Medicine Reports, 7(2), 124-135. SPRINGERNATURE
Current Genetic Medicine Reports, 7(2), 124-135. Springer US
Current Genetic Medicine Reports, 7(2), 124-135. Springer US
Purpose of review - Breast cancer is the most common cancer among females in developed countries. Strategies such as early detection by breast cancer screening can reduce the burden of disease but have disadvantages including overdiagnosis and increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d2bb2f0eac1448abef349c894772b9
https://hdl.handle.net/1887/3195905
https://hdl.handle.net/1887/3195905