Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Inge M. Ambros"'
Autor:
Angela Martinez-Monleon, Hanna Kryh Öberg, Jennie Gaarder, Ana P. Berbegall, Niloufar Javanmardi, Anna Djos, Marek Ussowicz, Sabine Taschner-Mandl, Inge M. Ambros, Ingrid Øra, Bengt Sandstedt, Klaus Beiske, Ruth Ladenstein, Rosa Noguera, Peter F. Ambros, Lena Gordon Murkes, Gustaf Ljungman, Per Kogner, Susanne Fransson, Tommy Martinsson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract In neuroblastoma, MYCN amplification and 11q-deletion are important, although incomplete, markers of high-risk disease. It is therefore relevant to characterize additional alterations that can function as prognostic and/or predictive markers
Externí odkaz:
https://doaj.org/article/be646e3979c84617bde833d6925092df
Autor:
Karin Schmelz, Joern Toedling, Matt Huska, Maja C. Cwikla, Louisa-Marie Kruetzfeldt, Jutta Proba, Peter F. Ambros, Inge M. Ambros, Sengül Boral, Marco Lodrini, Celine Y. Chen, Martin Burkert, Dennis Guergen, Annabell Szymansky, Kathy Astrahantseff, Annette Kuenkele, Kerstin Haase, Matthias Fischer, Hedwig E. Deubzer, Falk Hertwig, Patrick Hundsdoerfer, Anton G. Henssen, Roland F. Schwarz, Johannes H. Schulte, Angelika Eggert
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Neuroblastoma is a devastating tumour in children. Here, the authors analyse multi-region patient samples using genomics and transcriptomics, revealing temporal and spatial heterogeneity and questioning the reliability of single-biopsy based diagnost
Externí odkaz:
https://doaj.org/article/2390ab09b04a41c28245bac3ed08f2c9
Autor:
Peter Peneder, Adrian M. Stütz, Didier Surdez, Manuela Krumbholz, Sabine Semper, Mathieu Chicard, Nathan C. Sheffield, Gaelle Pierron, Eve Lapouble, Marcus Tötzl, Bekir Ergüner, Daniele Barreca, André F. Rendeiro, Abbas Agaimy, Heidrun Boztug, Gernot Engstler, Michael Dworzak, Marie Bernkopf, Sabine Taschner-Mandl, Inge M. Ambros, Ola Myklebost, Perrine Marec-Bérard, Susan Ann Burchill, Bernadette Brennan, Sandra J. Strauss, Jeremy Whelan, Gudrun Schleiermacher, Christiane Schaefer, Uta Dirksen, Caroline Hutter, Kjetil Boye, Peter F. Ambros, Olivier Delattre, Markus Metzler, Christoph Bock, Eleni M. Tomazou
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Liquid biopsies enable minimally invasive applications for diagnosis and treatment monitoring. Here the authors analyse fragmentation patterns of circulating tumour DNA on multiple levels and develop a bioinformatic tool, LIQUORICE, to accurately det
Externí odkaz:
https://doaj.org/article/00ea02e3e86d482ea6b429b513216011
Autor:
Tamara Weiss, Sabine Taschner-Mandl, Lukas Janker, Andrea Bileck, Fikret Rifatbegovic, Florian Kromp, Helena Sorger, Maximilian O. Kauer, Christian Frech, Reinhard Windhager, Christopher Gerner, Peter F. Ambros, Inge M. Ambros
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Schwann cells (SCs) can acquire a repair phenotype following nerve injury. Here, the authors show that stromal SCs in ganglioneuromas express nerve-repair genes. Importantly, neuroblastoma cells respond to repair-related SCs increasing neuronal diffe
Externí odkaz:
https://doaj.org/article/bbebc8510b0142cda49d7e4b7259747d
Autor:
Tamara Weiss, Sabine Taschner-Mandl, Lukas Janker, Andrea Bileck, Fikret Rifatbegovic, Florian Kromp, Helena Sorger, Maximilian O. Kauer, Christian Frech, Reinhard Windhager, Christopher Gerner, Peter F. Ambros, Inge M. Ambros
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 10, Iss 1S, Pp 4-5 (2022)
Externí odkaz:
https://doaj.org/article/9adf3010e9a74942ac9fe980b7fa1558
Publikováno v:
Frontiers in Oncology, Vol 4 (2014)
Neuroblastoma serves as a paradigm for applying tumor genomic data for determining patient prognosis and thus for treatment allocation. MYCN status, i.e. amplified vs. non-amplified, was one of the very first biomarkers in oncology to discriminate ag
Externí odkaz:
https://doaj.org/article/263797fb779841b8aaa99bc4c16c9197
Autor:
Peter F. Ambros, Inge M. Ambros, Ruth Ladenstein, Neil Jones, Godfrey C.F. Chan, Georg Ebetsberger-Dachs, Martin Benesch, Marek Ussowicz, Roman Crazzolara, Ulrike Pötschger, Andrea Ziegler, Georg Mann, Clemens Brunner, Fikret Rifatbegovic, M. Reza Abbasi
Supplementary Table S4. Focal copy number aberrations detected in the relapse samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::632e117d0f367aa990bb4f673db4a16c
https://doi.org/10.1158/1078-0432.22468566
https://doi.org/10.1158/1078-0432.22468566
Autor:
Peter F. Ambros, Inge M. Ambros, Ruth Ladenstein, Neil Jones, Godfrey C.F. Chan, Georg Ebetsberger-Dachs, Martin Benesch, Marek Ussowicz, Roman Crazzolara, Ulrike Pötschger, Andrea Ziegler, Georg Mann, Clemens Brunner, Fikret Rifatbegovic, M. Reza Abbasi
Supplementary Fig. S1: Stepwise accumulation of segmental chromosomal aberrations (SCAs) in chromosome 7 of the case study. Supplementary Fig. S2: Whole genome views of 10 different samples of a single stage 4 neuroblastoma patient. Supplementary Fig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a39a65785ba509521a7f9feee2f63a95
https://doi.org/10.1158/1078-0432.22468581.v1
https://doi.org/10.1158/1078-0432.22468581.v1
Autor:
Peter F. Ambros, Inge M. Ambros, Ruth Ladenstein, Neil Jones, Godfrey C.F. Chan, Georg Ebetsberger-Dachs, Martin Benesch, Marek Ussowicz, Roman Crazzolara, Ulrike Pötschger, Andrea Ziegler, Georg Mann, Clemens Brunner, Fikret Rifatbegovic, M. Reza Abbasi
Purpose: Tumor relapse is the most frequent cause of death in stage 4 neuroblastomas. Since genomic information on the relapse precursor cells could guide targeted therapy, our aim was to find the most appropriate tissue for identifying relapse-seedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3864bdab69c87a14b5abcb3607932e
https://doi.org/10.1158/1078-0432.c.6526992.v1
https://doi.org/10.1158/1078-0432.c.6526992.v1
Autor:
Peter F. Ambros, Karoline Ehlert, Felix Schriegel, Marie Bernkopf, Holger N. Lode, Nikolai Siebert, Inge M. Ambros, Sabine Taschner-Mandl, Guenter Henze, Uwe Grunwald
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 148:2581-2588
Purpose Neuroblastoma (NB) is the most frequent extracranial tumor in children. The detection of bone marrow (BM) involvement is crucial for correct staging and risk-adapted treatment. We compared three methods regarding the detection of NB involveme