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pro vyhledávání: '"Inge L. Werkman"'
Autor:
Inge L. Werkman, Marissa L. Dubbelaar, Pieter van der Vlies, Jelkje J. de Boer-Bergsma, Bart J. L. Eggen, Wia Baron
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-18 (2020)
Abstract Background Multiple sclerosis (MS) is an inflammation-mediated demyelinating disease of the central nervous system that eventually results in secondary axonal degeneration due to remyelination failure. Successful remyelination is orchestrate
Externí odkaz:
https://doaj.org/article/093370fa1b464b87adfed57d7737a7d8
Publikováno v:
Cellular and Molecular Life Sciences
Macroglia, comprising astrocytes and oligodendroglial lineage cells, have long been regarded as uniform cell types of the central nervous system (CNS). Although regional morphological differences between these cell types were initially described afte
Publikováno v:
Journal of Neurochemistry, 156(5). Blackwell Publishing Ltd
Journal of Neurochemistry
Journal of Neurochemistry
Remyelination is a regenerative process that is essential to recover saltatory conduction and to prevent neurodegeneration upon demyelination. The formation of new myelin involves the differentiation of oligodendrocyte progenitor cells (OPCs) toward
Autor:
Sho Morioka, Daiki Kajioka, Yusuke Yamaoka, Rochelle M. Ellison, Turan Tufan, Inge L. Werkman, Shinji Tanaka, Brady Barron, Satoshi T. Ito, Sarah Kucenas, Mark D. Okusa, Kodi S. Ravichandran
Publikováno v:
Cell. 185:4887-4903.e17
Our bodies turn over billions of cells daily via apoptosis and are in turn cleared by phagocytes via the process of "efferocytosis." Defects in efferocytosis are now linked to various inflammatory diseases. Here, we designed a strategy to boost effer
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports, 10(1):532. Nature Publishing Group
Scientific Reports
Scientific Reports, 10(1):532. Nature Publishing Group
Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system which eventually results in axonal loss mainly due to failure of remyelination. Previously we have shown that the persistent presence of stable astrocyte-derived
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports, 8(1):2113. Nature Publishing Group
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports, 8(1):2113. Nature Publishing Group
Multiple sclerosis (MS) is a chronic inflammatory disease characterized by the formation of demyelinated lesions in the central nervous system. At later stages of the disease repair in the form of remyelination often fails, which leads to axonal dege