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Autor:
Niloufar Haque, Sabiha Khatoon, Hitoshi Tanimukai, Jin-Jing Pei, Cheng-Xin Gong, Ezzat El-Akkad, Jian-Zhi Wang, Inge Grundke-Iqba, Ichiro Tsujio, K. Iqbal, Alejandra del C. Alonso
Publikováno v:
Journal of Molecular Neuroscience. 20:425-430
Neurofibrillary degeneration has primary and pivotal involvement in the pathogenesis of Alzheimer disease (AD) and other tauopathies. The inhibition of this lesion offers a promising therapeutic approach. The microtubule- associated protein (MAP) tau