Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Inge Bruggeman"'
Autor:
Marjolein Carron, Attila Placido Sachslehner, Munevver Burcu Cicekdal, Inge Bruggeman, Suzan Demuynck, Bahar Golabi, Elfride De Baere, Wim Declercq, Erwin Tschachler, Kris Vleminckx, Leopold Eckhart
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Cornified skin appendages, such as hair and nails, are major evolutionary innovations of terrestrial vertebrates. Human hair and nails consist largely of special intermediate filament proteins, known as hair keratins, which are expressed und
Externí odkaz:
https://doaj.org/article/a710d9a58fc84d2b8c16e5cff7cd038f
Autor:
Karel F. A. Van Damme, Pieter Hertens, Arne Martens, Elisabeth Gilis, Dario Priem, Inge Bruggeman, Amelie Fossoul, Jozefien Declercq, Helena Aegerter, Andy Wullaert, Tino Hochepied, Esther Hoste, Lieselotte Vande Walle, Mohamed Lamkanfi, Savvas N. Savvides, Dirk Elewaut, Bart N. Lambrecht, Geert van Loo
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract A20 serves as a critical brake on NF-κB-dependent inflammation. In humans, polymorphisms in or near the TNFAIP3/A20 gene have been linked to various inflammatory disorders, including systemic lupus erythematosus (SLE) and rheumatoid arthrit
Externí odkaz:
https://doaj.org/article/0bf2e4c99bae45e2afbc4924a4035aa2
Autor:
Philippe De Groote, Sasker Grootjans, Saskia Lippens, Chantal Eichperger, Kirsten Leurs, Irene Kahr, Giel Tanghe, Inge Bruggeman, Wouter De Schamphelaire, Corinne Urwyler, Peter Vandenabeele, Jurgen Haustraete, Wim Declercq
Publikováno v:
BioTechniques, Vol 60, Iss 5, Pp 252-259 (2016)
In contrast to most common gene delivery techniques, lentiviral vectors allow targeting of almost any mammalian cell type, even non-dividing cells, and they stably integrate in the genome. Therefore, these vectors are a very powerful tool for biomedi
Externí odkaz:
https://doaj.org/article/0c60e177baf14bdba81dd1ed7bc1ad13
Autor:
Yves Dondelinger, Wim Declercq, Sylvie Montessuit, Ria Roelandt, Amanda Goncalves, Inge Bruggeman, Paco Hulpiau, Kathrin Weber, Clark A. Sehon, Robert W. Marquis, John Bertin, Peter J. Gough, Savvas Savvides, Jean-Claude Martinou, Mathieu J.M. Bertrand, Peter Vandenabeele
Publikováno v:
Cell Reports, Vol 7, Iss 4, Pp 971-981 (2014)
Although mixed lineage kinase domain-like (MLKL) protein has emerged as a specific and crucial protein for necroptosis induction, how MLKL transduces the death signal remains poorly understood. Here, we demonstrate that the full four-helical bundle d
Externí odkaz:
https://doaj.org/article/861d16d1f33d45d7a36b240ef8000808
Publikováno v:
Communications Biology, Vol 1, Iss 1, Pp 1-13 (2018)
COMMUNICATIONS BIOLOGY
COMMUNICATIONS BIOLOGY
Necroptotic signaling converges in the assembly of a cytosolic signaling platform, the necrosome, with the activation of its downstream effector, MLKL. RIPK1 and RIPK3, key components of the necrosome, act as signaling intermediates for the activatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6adbe9acde0bff1ddfee42773d79e36b
http://link.springer.com/article/10.1038/s42003-017-0007-1
http://link.springer.com/article/10.1038/s42003-017-0007-1
Autor:
Kathrin Weber, Inge Bruggeman, Peter Vandenabeele, Yves Dondelinger, Yann Estornes, Serge Lebecque, Mathieu J.M. Bertrand, Marion MacFarlane, Adam Peall
Publikováno v:
Cell Death & Disease
CELL DEATH & DISEASE
Cell Death and Disease, Vol 9, Iss 5, Pp 1-13 (2018)
CELL DEATH & DISEASE
Cell Death and Disease, Vol 9, Iss 5, Pp 1-13 (2018)
The sensitivity of cells to death receptor-induced apoptosis is commonly controlled by multiple checkpoints in order to limit induction of excessive or unnecessary death. Although cytotoxic in various cancer cells, tumor necrosis factor (TNF)-related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8eb9ee23f3f36863d1411ce77ed371d
http://europepmc.org/articles/PMC5931557
http://europepmc.org/articles/PMC5931557
Autor:
Sylvie Montessuit, Amanda Gonçalves, Robert W. Marquis, Wim Declercq, Paco Hulpiau, Peter Vandenabeele, Clark A. Sehon, John Bertin, Ria Roelandt, Inge Bruggeman, Mathieu J.M. Bertrand, Jean-Claude Martinou, Peter J. Gough, Yves Dondelinger, Savvas N. Savvides, Kathrin Weber
Publikováno v:
Cell Reports, Vol 7, Iss 4, Pp 971-981 (2014)
Cell reports
CELL REPORTS
Cell reports
CELL REPORTS
SummaryAlthough mixed lineage kinase domain-like (MLKL) protein has emerged as a specific and crucial protein for necroptosis induction, how MLKL transduces the death signal remains poorly understood. Here, we demonstrate that the full four-helical b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a4fc317879467a1d55fd483cda0e53
http://www.sciencedirect.com/science/article/pii/S2211124714003283
http://www.sciencedirect.com/science/article/pii/S2211124714003283
Autor:
Tom Delanghe, Dario Priem, Tinneke Delvaeye, Franky Van Herreweghe, Peter Vandenabeele, Mathieu J.M. Bertrand, Yves Dondelinger, Diego Rojas-Rivera, Inge Bruggeman
Publikováno v:
Nature cell biology. 19(10)
TNF is a master proinflammatory cytokine whose pathogenic role in inflammatory disorders can, in certain conditions, be attributed to RIPK1 kinase-dependent cell death. Survival, however, is the default response of most cells to TNF stimulation, indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8c973a5363862e187f57135657aebc
https://pubmed.ncbi.nlm.nih.gov/28920952
https://pubmed.ncbi.nlm.nih.gov/28920952
Autor:
Irene Kahr, Kirsten Leurs, Peter Vandenabeele, Wouter De Schamphelaire, Wim Declercq, Jurgen Haustraete, Chantal Eichperger, Sasker Grootjans, Giel Tanghe, Inge Bruggeman, Saskia Lippens, Corinne Urwyler, Philippe De Groote
Publikováno v:
BioTechniques. 60(5)
In contrast to most common gene delivery techniques, lentiviral vectors allow targeting of almost any mammalian cell type, even non-dividing cells, and they stably integrate in the genome. Therefore, these vectors are a very powerful tool for biomedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d04f26481a6a5310537855b61e75f1
https://pubmed.ncbi.nlm.nih.gov/27177818
https://pubmed.ncbi.nlm.nih.gov/27177818
Autor:
Inge Bruggeman, Wim Declercq, Michael Devos, Philippe De Groote, Barbara Gilbert, Saskia Lippens, Kirsten Leurs, Peter Vandenabeele
Publikováno v:
Experimental dermatology. 22(7)
Loss of functional hairless (HR) transcriptional repressor leads to utricle formation and congenital hair loss both in mice and men. Studies in mice have shown that this is preceded by overexpression of caspase-14 at the infundibulum in the hair foll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd0c29218283ba804f3e3327a082ab14
https://pubmed.ncbi.nlm.nih.gov/23800061
https://pubmed.ncbi.nlm.nih.gov/23800061