Výsledky vyhledávání - "Inge, Seibold"

Lack of TNFR2 expression by CD4+T cells exacerbates experimental colitis

Autor: Johanna M. Dayer Schneider, Inge Seibold, Nikolina Saxer-Sekulic, Bruno E. Paredes, Leslie Saurer, Christoph Mueller

Publikováno v: European Journal of Immunology. 39:1743-1753

TNF plays fundamental roles in the induction and perpetuation of inflammation. The effects of TNF are mediated through TNF receptor (TNFR) 1 or 2. As these two receptors mediate different functions, selective targeting of one receptor may represent a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::caa5ce7ab6808be025c5e294d7bfcd6b
https://doi.org/10.1002/eji.200839132

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Lack of TNFR2 expression by CD4(+) T cells exacerbates experimental colitis

Autor: Johanna, Dayer Schneider, Inge, Seibold, Nikolina, Saxer-Sekulic, Bruno E, Paredes, Leslie, Saurer, Christoph, Mueller

Publikováno v: European journal of immunology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::93ff221291a164bc55d0515726faa1fa

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Transmembrane tumor necrosis factor is a potent inducer of colitis even in the absence of its secreted form

Autor: Silvia Rihs, Martin A. Imboden, Caroline Buri, Christoph Mueller, Inge Seibold, Nadia Corazza, Thomas Brunner

Publikováno v: Gastroenterology. 127:816-825

Background & Aims: Tumor necrosis factor (TNF) is cleaved proteolytically from a 26-kilodalton transmembrane precursor protein into secreted 17-kilodalton monomers. Transmembrane (tm) and secreted trimeric TNF are biologically active and may mediate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9abacde0dc4e36ad468d716cdcb60df
https://doi.org/10.1053/j.gastro.2004.06.036

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Virus-Induced Activation of Self-Specific TCRαβ CD8αα Intraepithelial Lymphocytes Does Not Abolish Their Self-Tolerance in the Intestine

Autor: Leslie Saurer, Inge Seibold, Claudio Vallan, Christoph Mueller, Silvia Rihs, Tilman Dumrese

Publikováno v: Scopus-Elsevier

TCRαβ CD8αα intestinal intraepithelial lymphocytes (IEL) represent an enigmatic subset of T cells, particularly, in regard to their potential functions and the apparent persistence of cells expressing self-specific TCR. We have used mice that are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed75211072df1c0b5053e2069965089
https://doi.org/10.4049/jimmunol.172.7.4176

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Cutting Edge: Stimulation with the Cognate Self-Antigen Induces Expression of the Ly49A Receptor on Self-Reactive T Cells Which Modulates Their Responsiveness

Autor: Christoph Mueller, Inge Seibold, Leslie Saurer, Claudio Vallan, Werner Held

Publikováno v: The Journal of Immunology. 171:6334-6338

NK cell self-tolerance is maintained by inhibitory receptors specific for MHC class I molecules. Inhibitory NK receptors are also expressed on memory CD8 T cells but their biological relevance on T cells is unclear. In this study, we describe the exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a58f47ab4d2c31bb6d02c0923215589
https://doi.org/10.4049/jimmunol.171.12.6334

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Virus-induced activation of self-specific TCR alpha beta CD8 alpha alpha intraepithelial lymphocytes does not abolish their self-tolerance in the intestine

Autor: Leslie, Saurer, Inge, Seibold, Silvia, Rihs, Claudio, Vallan, Tilman, Dumrese, Christoph, Mueller

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 172(7)

TCRalphabeta CD8alphaalpha intestinal intraepithelial lymphocytes (IEL) represent an enigmatic subset of T cells, particularly, in regard to their potential functions and the apparent persistence of cells expressing self-specific TCR. We have used mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::51564699d51c00da76778e42953bd891
https://pubmed.ncbi.nlm.nih.gov/15034030

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