Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Inga-Marie Schaefer"'
Autor:
Inga-Marie Schaefer, Yuexiang Wang, Cher-wei Liang, Nacef Bahri, Anna Quattrone, Leona Doyle, Adrian Mariño-Enríquez, Alexandra Lauria, Meijun Zhu, Maria Debiec-Rychter, Susanne Grunewald, Jaclyn F. Hechtman, Armelle Dufresne, Cristina R. Antonescu, Carol Beadling, Ewa T. Sicinska, Matt van de Rijn, George D. Demetri, Marc Ladanyi, Christopher L. Corless, Michael C. Heinrich, Chandrajit P. Raut, Sebastian Bauer, Jonathan A. Fletcher
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-6 (2017)
In gastrointestinal stromal tumours early mutations in known genes are frequently followed by chromosome 14q deletion. Here the authors find mutations resulting in loss of MAX protein expression conserved between primary tumours and metastases in the
Externí odkaz:
https://doaj.org/article/f99b7b0f7dfb4944b7bbfdf9272bbf4d
Autor:
Henriette Quack, Luise Erpenbeck, Hendrik A. Wolff, Thilo Sprenger, Cornelia S. Seitz, Michael P. Schön, Steffen Neumann, Kathrin Stanek, B. Michael Ghadimi, Beate Michels, Peter Middel, Inga-Marie Schaefer, Torsten Liersch, Lena-Christin Conradi
Publikováno v:
Case Reports in Oncology, Vol 6, Iss 3, Pp 609-615 (2013)
Leukocytoclastic vasculitis is a multicausal systemic inflammatory disease of the small vessels, histologically characterized by inflammation and deposition of both nuclear debris and fibrin in dermal postcapillary venules. The clinical picture typic
Externí odkaz:
https://doaj.org/article/fa063515e38a4c9ea38338a24576acdc
Publikováno v:
Case Reports in Oncology, Vol 4, Iss 3, Pp 505-511 (2011)
Imatinib mesylate, as treatment for gastrointestinal stromal tumors (GIST), has dramatically changed the prognosis for survival – not only because it is efficacious, but also because it attracted attention to this malignant disease. GIST is now a w
Externí odkaz:
https://doaj.org/article/ffcdcc2b66f64ade9e0a1f885e825acb
Autor:
Tserendulam Batsukh, Yvonne Schulz, Stephan Wolf, Tamara I Rabe, Thomas Oellerich, Henning Urlaub, Inga-Marie Schaefer, Silke Pauli
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52640 (2012)
BACKGROUND: Mutations in the chromodomain helicase DNA binding protein 7 gene (CHD7) lead to CHARGE syndrome, an autosomal dominant multiple malformation disorder. Proteins involved in chromatin remodeling typically act in multiprotein complexes. We
Externí odkaz:
https://doaj.org/article/c390eda618624a06ad2d805e6c3fef91
Autor:
Inga-Marie Schaefer, Matthew L. Hemming, Meijun Z. Lundberg, Matthew P. Serrata, Isabel Goldaracena, Ninning Liu, Peng Yin, Joao A. Paulo, Steven P. Gygi, Suzanne George, Jeffrey A. Morgan, Monica M. Bertagnolli, Ewa T. Sicinska, Chen Chu, Shanshan Zheng, Adrian Mariño-Enríquez, Jason L. Hornick, Chandrajit P. Raut, Wen-Bin Ou, George D. Demetri, Sinem K. Saka, Jonathan A. Fletcher
Publikováno v:
British Journal of Cancer. 127:2072-2085
Advanced gastrointestinal stromal tumour (GIST) is characterised by genomic perturbations of key cell cycle regulators. Oncogenic activation of CDK4/6 results in RB1 inactivation and cell cycle progression. Given that single-agent CDK4/6 inhibitor th
Publikováno v:
Surgical Oncology Clinics of North America. 31:321-340
Autor:
Inga‐Marie Schaefer, Xiaohua Qian
Publikováno v:
Cancer Cytopathology.
Autor:
Inga-Marie Schaefer, Jason L. Hornick
Publikováno v:
Semin Diagn Pathol
The SWItch Sucrose Non-Fermentable (SWI/SNF) chromatin remodeling complex is a large multi-subunit protein assembly that orchestrates chromatin compaction and accessibility for gene transcription in an ATP-dependent manner. As a key epigenetic regula
Autor:
Silvia Stacchiotti, Anna Maria Frezza, George D. Demetri, Jean-Yves Blay, Jyoti Bajpai, Giacomo G. Baldi, Elizabeth H. Baldini, Robert S. Benjamin, Sylvie Bonvalot, Judith V.M.G. Bovée, Dario Callegaro, Paolo G. Casali, Sandra P. D'Angelo, Elizabeth J. Davis, Angelo P. Dei Tos, Elizabeth G. Demicco, Jayesh Desai, Palma Dileo, Mikael Eriksson, Hans Gelderblom, Suzanne George, Rebecca A. Gladdy, Mrinal M. Gounder, Abha A. Gupta, Rick Haas, Andrea Hayes, Peter Hohenberger, Kevin B. Jones, Robin L. Jones, Bernd Kasper, Akira Kawai, David G. Kirsch, Eugenie S. Kleinerman, Axel Le Cesne, Roberta Maestro, Javier Martin Broto, Robert G. Maki, Aisha B. Miah, Emanuela Palmerini, Shreaskumar R. Patel, Chandrajit P. Raut, Albiruni R.A. Razak, Damon R. Reed, Piotr Rutkowski, Roberta G. Sanfilippo, Marta Sbaraglia, Inga-Marie Schaefer, Dirk C. Strauss, Sandra J. Strauss, William D. Tap, David M. Thomas, Annalisa Trama, Jonathan C. Trent, Winette T.A. van der Graaf, Winan J. van Houdt, Margaret von Mehren, Breelyn A. Wilky, Christopher D.M. Fletcher, Alessandro Gronchi, Rosalba Miceli, Andrew J. Wagner
Publikováno v:
Cancer Treatment Reviews, 110. ELSEVIER SCI LTD
Background: In ultra-rare sarcomas (URS) the conduction of prospective, randomized trials is challenging. Data from retrospective observational studies (ROS) may represent the best evidence available. ROS implicit limitations led to poor acceptance b
Publikováno v:
Am J Clin Pathol
Objectives The SWI/SNF complex core subunit SMARCB1 is inactivated in a variety of neoplasms that share characteristic “rhabdoid” cytomorphology. The aim of this study was to evaluate SMARCB1-deficient soft tissue neoplasms on cytology to identif