Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Inga Siden‐Kiamos"'
Autor:
Elena Deligianni, Elisabetta Pizzi, Ioanna Kavelaki, Inga Siden-Kiamos, Filippo Umberto Sapienza, Rossella Fioravanti, Stefania Garzoli, Tomasino Pace, Marta Ponzi, Rino Ragno, Chiara Currà
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 23, Iss , Pp 87-93 (2023)
Malaria, an infectious disease with a tremendous impact on human health is caused by Plasmodium parasites, and transmitted by Anopheles mosquitoes. New approaches to control the disease involve transmission blocking strategies aiming to target the pa
Externí odkaz:
https://doaj.org/article/b4a84f3341384cad9c33280d4eec2cfb
Autor:
Claudia Camarero-Hoyos, Inés Bouzón-Arnáiz, Yunuen Avalos-Padilla, Antonino Nicolò Fallica, Lucía Román-Álamo, Miriam Ramírez, Emma Portabella, Ona Cuspinera, Daniela Currea-Ayala, Marc Orozco-Quer, Maria Ribera, Inga Siden-Kiamos, Lefteris Spanos, Valentín Iglesias, Benigno Crespo, Sara Viera, David Andreu, Elena Sulleiro, Francesc Zarzuela, Nerea Urtasun, Sandra Pérez-Torras, Marçal Pastor-Anglada, Elsa M. Arce, Diego Muñoz-Torrero, Xavier Fernàndez-Busquets
Publikováno v:
Pharmaceutics, Vol 16, Iss 10, p 1290 (2024)
Background/Objectives: YAT2150 is a first-in-class antiplasmodial compound that has been recently proposed as a new interesting drug for malaria therapy. Methods/Results: The fluorescence of YAT2150 rapidly increases upon its entry into Plasmodium, a
Externí odkaz:
https://doaj.org/article/9978acea5c204150aee39ceeca55d275
Autor:
Maria Andreadaki, Tomasino Pace, Felicia Grasso, Inga Siden‐Kiamos, Stefania Mochi, Leonardo Picci, Lucia Bertuccini, Marta Ponzi, Chiara Currà
Publikováno v:
MicrobiologyOpen, Vol 9, Iss 7, Pp n/a-n/a (2020)
Abstract Male and female Plasmodium gametocytes ingested by the Anopheles mosquitoes during a blood meal egress from the red blood cells by rupturing the two surrounding membranes, the parasitophorous vacuole and the red blood cell membranes. Protein
Externí odkaz:
https://doaj.org/article/50027665356547e2b00ca9631883daaa
Autor:
Maria Andreadaki, Eric Hanssen, Elena Deligianni, Cyrille Claudet, Kai Wengelnik, Vanessa Mollard, Geoffrey I. McFadden, Manouk Abkarian, Catherine Braun-Breton, Inga Siden-Kiamos
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Malaria parasites alternate between intracellular and extracellular stages and successful egress from the host cell is crucial for continuation of the life cycle. We investigated egress of Plasmodium berghei gametocytes, an essential process
Externí odkaz:
https://doaj.org/article/f364a0dae290472993a2c088f8fb673d
Autor:
Chiara Currà, Renate Gessmann, Tomasino Pace, Leonardo Picci, Giulia Peruzzi, Vassiliki Varamogianni-Mamatsi, Lefteris Spanos, Célia R. S. Garcia, Roberta Spaccapelo, Marta Ponzi, Inga Siden-Kiamos
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Oocyst rupture and release of malaria sporozoites is needed for transmission of parasites from vector to humans. Here the authors identify two proteins, which they name ORP1 and ORP2, that form heterodimers and are required for oocyst rupture.
Externí odkaz:
https://doaj.org/article/b3b8fc3e13a14db381a34a3a955abb2c
Autor:
Chiara Currà, Jessica Kehrer, Leandro Lemgruber, Patricia A G C Silva, Lucia Bertuccini, Fabiana Superti, Tomasino Pace, Marta Ponzi, Friedrich Frischknecht, Inga Siden-Kiamos, Gunnar R Mair
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222226 (2019)
Ookinetes, one of the motile and invasive forms of the malaria parasite, rely on gliding motility in order to establish an infection in the mosquito host. Here we characterize the protein PBANKA_0407300 which is conserved in the Plasmodium genus but
Externí odkaz:
https://doaj.org/article/c7e637ba3baf4302b2beb5d3c43f330c
Autor:
Elena Deligianni, Natalie C Silmon de Monerri, Paul J McMillan, Lucia Bertuccini, Fabiana Superti, Maria Manola, Lefteris Spanos, Christos Louis, Michael J Blackman, Leann Tilley, Inga Siden-Kiamos
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204083 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0201651.].
Externí odkaz:
https://doaj.org/article/54b2168a32f946c1867c4a2b7a36c198
Autor:
Elena Deligianni, Natalie C Silmon de Monerri, Paul J McMillan, Lucia Bertuccini, Fabiana Superti, Maria Manola, Lefteris Spanos, Christos Louis, Michael J Blackman, Leann Tilley, Inga Siden-Kiamos
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201651 (2018)
Pore forming proteins such as those belonging to the membrane attack/perforin (MACPF) family have important functions in many organisms. Of the five MACPF proteins found in Plasmodium parasites, three have functions in cell passage and one in host ce
Externí odkaz:
https://doaj.org/article/f60feafef58344a9889c39991e34b5f0
Autor:
Konstantinos Koussis, Evi Goulielmaki, Anna Chalari, Chrislaine Withers-Martinez, Inga Siden-Kiamos, Kai Matuschewski, Thanasis G Loukeris
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170260 (2017)
Site-2 proteases (S2P) belong to the M50 family of metalloproteases, which typically perform essential roles by mediating activation of membrane-bound transcription factors through regulated intramembrane proteolysis (RIP). Protease-dependent liberat
Externí odkaz:
https://doaj.org/article/1286f99e77064fc3bc23e28991c1b711
Autor:
Elisabet Martí Coma-Cros, Arnau Biosca, Joana Marques, Laura Carol, Patricia Urbán, Diana Berenguer, Maria Cristina Riera, Michael Delves, Robert E. Sinden, Juan José Valle-Delgado, Lefteris Spanos, Inga Siden-Kiamos, Paula Pérez, Krijn Paaijmans, Matthias Rottmann, Amedea Manfredi, Paolo Ferruti, Elisabetta Ranucci, Xavier Fernàndez-Busquets
Publikováno v:
Pharmaceutics, Vol 10, Iss 4, p 225 (2018)
Current strategies for the mass administration of antimalarial drugs demand oral formulations to target the asexual Plasmodium stages in the peripheral bloodstream, whereas recommendations for future interventions stress the importance of also target
Externí odkaz:
https://doaj.org/article/b295ff5e39894a82946f782bfd2b62ec