Výsledky vyhledávání

Transgenic overexpression of adenine nucleotide translocase 1 protects ischemic hearts against oxidative stress

Autor: Dirk Westermann, Carsten Tschöpe, Ursula Rauch, Ulf Landmesser, Heinz-Peter Schultheiss, Andrea Dörner, Inga Klumpe, Konstantinos Savvatis

Publikováno v: Journal of Molecular Medicine. 94:645-653

Ischemia impairs the adenine nucleotide translocase (ANT), which transports ADP and ATP across the inner mitochondrial membrane. We investigated whether ANT1 overexpression has protective effects on ischemic hearts. Myocardial infarction was induced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d6cb762cd5b6d451129af1a94dc79e
https://doi.org/10.1007/s00109-016-1413-4

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Adenine nucleotide translocase 1 expression affects enterovirus infection in human and murine hearts

Autor: Julia Winter, Heinz-Peter Schultheiss, Linda Ebermann, Heinz Zeichhardt, Karin Klingel, Inga Klumpe, Andrea Dörner, Uwe Kühl, Dirk Lassner

Publikováno v: International Journal of Cardiology. 172:e449-e452

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::511622959d9bc5196bc8f20bcf56b42b
https://doi.org/10.1016/j.ijcard.2013.12.315

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Transgenic overexpression of the adenine nucleotide translocase 1 protects cardiomyocytes against TGFβ1-induced apoptosis by stabilization of the mitochondrial permeability transition pore

Autor: Klaus-Dieter Schlüter, Yaser Abdallah, Hans Michael Piper, Heinz P. Schultheiss, Andrea Dörner, Tayyab Shahzad, Gerhild Euler, Inga Klumpe, Jacqueline Heger, Rainer Schulz

Publikováno v: Journal of Molecular and Cellular Cardiology. 53:73-81

Since adenine nucleotide translocase 1 (ANT1) overexpression improved cardiac function in rats with activated renin-angiotensin system (RAS) and angiotensin II is known to enhance transforming growth factor β (TGFβ) signaling in cardiomyocytes, we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63cb9efedc95f4335123f6f0c0643d04
https://doi.org/10.1016/j.yjmcc.2012.04.013

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The mitochondrial respiratory chain has a critical role in the antiviral process in Coxsackievirus B3-induced myocarditis

Autor: Linda Ebermann, Uwe Völker, Dirk Lassner, Sylwia Wika, Heinz Zeichhardt, Heinz-Peter Schultheiss, Karin Klingel, Andrea Dörner, Inga Klumpe, Ulrike Erben, Elke Hammer

Publikováno v: Laboratory Investigation. 92:125-134

Well-established differences in Coxsackievirus B3 (CVB3) elimination in resistant C57BL/6 and permissive A.SW/SnJ mice provide suitable models for studying the significance of the link between mitochondrial respiratory chain (RC), antioxidative stres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4669263773ff21900346afb3d62d7b
https://doi.org/10.1038/labinvest.2011.145

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Adenine nucleotide translocase 1 overexpression protects cardiomyocytes against hypoxia via increased ERK1/2 and AKT activation

Autor: Ulf Landmesser, Andrea Dörner, Inga Klumpe, Heinz-Peter Schultheiss, Jacqueline Heger, Ursula Rauch, Julia Winter

Publikováno v: Cellular signalling. 28(1)

The influence of mitochondrial function on intracellular signalling is currently under intense investigation. In this regard, we analysed the effect of adenine nucleotide translocase 1 (ANT1), which facilitates the exchange of ADP and ATP across the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e73cc3d09592cdfebb45cef9c813d2d
https://pubmed.ncbi.nlm.nih.gov/26548633

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