Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Inga Hoffmann"'
Autor:
Paul Jank, Jonas Leichsenring, Svenja Kolb, Inga Hoffmann, Philip Bischoff, Catarina Alisa Kunze, Mihnea P. Dragomir, Moritz Gleitsmann, Moritz Jesinghaus, Wolfgang D. Schmitt, Hagen Kulbe, Christine Sers, Albrecht Stenzinger, Jalid Sehouli, Ioana Elena Braicu, Christina Westhoff, David Horst, Carsten Denkert, Stefan Gröschel, Eliane T. Taube
Publikováno v:
Journal of Ovarian Research, Vol 16, Iss 1, Pp 1-13 (2023)
Abstract Background Mechanisms of development and progression of high-grade serous ovarian cancer (HGSOC) are poorly understood. EVI1 and PARP1, part of TGF-ß pathway, are upregulated in cancers with DNA repair deficiencies with DNA repair deficienc
Externí odkaz:
https://doaj.org/article/6475539f264d451aaaf6ee746f0741b3
Autor:
Inga Hoffmann, Mihnea P. Dragomir, Nanna Monjé, Carlotta Keunecke, Catarina Alisa Kunze, Simon Schallenberg, Sofya Marchenko, Wolfgang D. Schmitt, Hagen Kulbe, Jalid Sehouli, Ioana Elena Braicu, Paul Jank, Carsten Denkert, Silvia Darb-Esfahani, David Horst, Bruno V. Sinn, Christine Sers, Philip Bischoff, Eliane T. Taube
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 44, Iss , Pp 100934- (2023)
Background: The enzyme indoleamine 2,3-dioxygenase 1 (IDO1) plays a crucial role in regulating the immune system's response to tumors, but its exact role in cancer, especially in high-grade serous ovarian cancer (HGSOC), remains controversial. We aim
Externí odkaz:
https://doaj.org/article/b6f31ec2a1e44774a733c2bd83866df5
Autor:
Philipp Jurmeister, Stefanie Glöß, Renée Roller, Maximilian Leitheiser, Simone Schmid, Liliana H. Mochmann, Emma Payá Capilla, Rebecca Fritz, Carsten Dittmayer, Corinna Friedrich, Anne Thieme, Philipp Keyl, Armin Jarosch, Simon Schallenberg, Hendrik Bläker, Inga Hoffmann, Claudia Vollbrecht, Annika Lehmann, Michael Hummel, Daniel Heim, Mohamed Haji, Patrick Harter, Benjamin Englert, Stephan Frank, Jürgen Hench, Werner Paulus, Martin Hasselblatt, Wolfgang Hartmann, Hildegard Dohmen, Ursula Keber, Paul Jank, Carsten Denkert, Christine Stadelmann, Felix Bremmer, Annika Richter, Annika Wefers, Julika Ribbat-Idel, Sven Perner, Christian Idel, Lorenzo Chiariotti, Rosa Della Monica, Alfredo Marinelli, Ulrich Schüller, Michael Bockmayr, Jacklyn Liu, Valerie J. Lund, Martin Forster, Matt Lechner, Sara L. Lorenzo-Guerra, Mario Hermsen, Pascal D. Johann, Abbas Agaimy, Philipp Seegerer, Arend Koch, Frank Heppner, Stefan M. Pfister, David T. W. Jones, Martin Sill, Andreas von Deimling, Matija Snuderl, Klaus-Robert Müller, Erna Forgó, Brooke E. Howitt, Philipp Mertins, Frederick Klauschen, David Capper
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Sinonasal tumour diagnosis can be complicated by the heterogeneity of disease and classification systems. Here, the authors use machine learning to classify sinonasal undifferentiated carcinomas into 4 molecular classe with differences in differentia
Externí odkaz:
https://doaj.org/article/6b6e398cca1d45b0ab123d7e7294892a
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 10, Pp 2113-2123 (2014)
The genome of the rice blast fungus Magnaporthe oryzae codes for two proteins with N-terminal dioxygenase (DOX) and C-terminal cytochrome P450 (CYP) domains, respectively. One of them, MGG_13239, was confirmed as 7,8-linoleate diol synthase by prokar
Externí odkaz:
https://doaj.org/article/da2250fc9b7547e8b8cb2eb0028e962d
Autor:
Inga Hoffmann, Ernst H. Oliw
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 12, Pp 3471-3480 (2013)
Fusarium oxysporum is a devastating plant pathogen that oxidizes C18 fatty acids sequentially to jasmonates. The genome codes for putative dioxygenase (DOX)-cytochrome P450 (CYP) fusion proteins homologous to linoleate diol synthases (LDSs) and the a
Externí odkaz:
https://doaj.org/article/11c935ad48f948d287f2390de683b90a
Publikováno v:
Journal of Lipid Research, Vol 52, Iss 11, Pp 1995-2004 (2011)
Seven Z-octadecenoic acids having the double bond located in positions 6Z to 13Z were photooxidized. The resulting hydroperoxy-E-octadecenoic acids [HpOME(E)] were resolved by chiral phase-HPLC-MS, and the absolute configurations of the enantiomers w
Externí odkaz:
https://doaj.org/article/69e875a5b7224c2596e61af10e5b2fb8
Autor:
Claudia Vollbrecht, Inga Hoffmann, Annika Lehmann, Sabine Merkelbach-Bruse, Jana Fassunke, Svenja Wagener-Ryczek, Markus Ball, Lora Dimitrova, Arndt Hartmann, Robert Stöhr, Ramona Erber, Wilko Weichert, Nicole Pfarr, Lisa Bohlmann, Andreas Jung, Wolfgang Dietmaier, Manfred Dietel, David Horst, Michael Hummel
Publikováno v:
Virchows Archiv. 482:697-706
Precision oncology based on specific molecular alterations requires precise and reliable detection of therapeutic targets in order to initiate the optimal treatment. In many European countries—including Germany—assays employed for this purpose ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a855143283d4575525aced9df5df0d
https://doi.org/10.1007/s00428-022-03445-x
https://doi.org/10.1007/s00428-022-03445-x
Autor:
Sofya Marchenko, Iris Piwonski, Inga Hoffmann, Bruno Valentin Sinn, Catarina Alisa Kunze, Nanna Monjé, Jonathan Pohl, Hagen Kulbe, Wolfgang Daniel Schmitt, Sylvia Darb-Esfahani, Elena Ioana Braicu, Ann-Christin von Brünneck, Jalid Sehouli, Carsten Denkert, David Horst, Korinna Jöhrens, Eliane Tabea Taube
Publikováno v:
Journal of cancer research and clinical oncology.
Purpose In recent years the tumor microenvironment and its interaction with the tumor has emerged into research focus with increased attention to the composition of Tumor-infiltrating lymphocytes. We wanted to quantify the composition of Regulatory T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a421e4ed330257d61c9e92df197e1f
https://pubmed.ncbi.nlm.nih.gov/35763108
https://pubmed.ncbi.nlm.nih.gov/35763108
Autor:
David Capper, Peggy Wolkenstein, Inga Hoffmann, Claudia Vollbrecht, Frederick Klauschen, Ines Koch, Philipp Jurmeister, Niklas Wrede, Maximilian von Laffert
Publikováno v:
Pathology, research and practice. 229
Mucosal melanomas arise from the mucosal lining of various organs. Their etiology is currently unknown and there are no tissue-based methods to differentiate it from cutaneous melanomas. Furthermore, prognostic and predictive markers (e.g. for immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be7b5d76e8957c4dd0035051c31c890c
https://pubmed.ncbi.nlm.nih.gov/34844086
https://pubmed.ncbi.nlm.nih.gov/34844086
Autor:
Jana Ihlow, Nanna Monjé, Inga Hoffmann, Philip Bischoff, Bruno Valentin Sinn, Wolfgang Daniel Schmitt, Catarina Alisa Kunze, Sylvia Darb-Esfahani, Hagen Kulbe, Elena Ioana Braicu, Jalid Sehouli, Carsten Denkert, David Horst, Eliane Tabea Taube
Publikováno v:
Cancers; Volume 14; Issue 19; Pages: 4620
RGS2 regulates G-protein signaling by accelerating hydrolysis of GTP and has been identified as a potentially druggable target in carcinomas. Since the prognosis of patients with high-grade serous ovarian carcinoma (HGSOC) remains utterly poor, new t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d1ead784a638dc3662f988c9b35723
https://doi.org/10.3390/cancers14194620
https://doi.org/10.3390/cancers14194620