Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Inga E. Haedicke"'
Autor:
Joris Tchouala Nofiele, Weiran Cheng, Inga E. Haedicke, Tameshwar Ganesh, Xiao-an Zhang, Hai-Ling Margaret Cheng
Publikováno v:
Molecular Imaging, Vol 13 (2014)
The lung remains one of the most challenging organs to image using magnetic resonance imaging (MRI) due to intrinsic rapid signal decay. However, unlike conventional modalities such as computed tomography, MRI does not involve radiation and can provi
Externí odkaz:
https://doaj.org/article/f3b9254d0129487794b578b2a2e21318
Autor:
Andrei Venter, Daniel A. Szulc, Sadi Loai, Inga E. Haedicke, Tameshwar Ganesh, Hai-Ling Margaret Cheng
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
MRI for non-invasive cell tracking is recognized for enabling pre-clinical research on stem cell therapy. Yet, adoption of cellular imaging in stem cell research has been restricted to sites with experience in MR contrast agent synthesis and to small
Publikováno v:
Contrast Media & Molecular Imaging
Noninvasive cell tracking in vivo has the potential to advance stem cell-based therapies into the clinic. Magnetic resonance imaging (MRI) provides an excellent image-guidance platform; however, existing MR cell labeling agents are fraught with limit
Publikováno v:
Contrast Media & Molecular Imaging, Vol 2019 (2019)
Noninvasive cell tracking in vivo has the potential to advance stem cell-based therapies into the clinic. Magnetic resonance imaging (MRI) provides an excellent image-guidance platform; however, existing MR cell labeling agents are fraught with limit
Autor:
Sadi Loai, Hai-Ling Margaret Cheng, Xiao-an Zhang, Zahra Mirzaei, Craig A. Simmons, Inga E. Haedicke
Publikováno v:
Journal of Magnetic Resonance Imaging. 44:1456-1463
PURPOSE To investigate the feasibility of high-sensitivity cellular MRI of embryonic stem (ES) cells using a novel cell permeable and cell retentive T1 contrast agent. MATERIALS AND METHODS Mouse ES cells were labeled with a novel manganese porphyrin
Autor:
Donna H. Murrell, Tan Li, Amanda M. Hamilton, Xiao-an Zhang, Yong Le K. Zhu, Joris Nofiele, Paula J. Foster, Timothy J. Scholl, Inga E. Haedicke, Hai-Ling Margaret Cheng, Francisco Martinez
Publikováno v:
Chemical Science. 7:4308-4317
Magnetic resonance imaging (MRI) is a preferred technique for noninvasively monitoring the fate of implanted cells, such as stem cells and immune cells in vivo. Cellular MRI requires contrast agents (CAs) to label the cells of interest. Despite promi
Publikováno v:
Journal of Magnetic Resonance Imaging. 41:397-403
Purpose To evaluate a new formulation of manganese porphyrin as a potential gadolinium (Gd)-free extracellular magnetic resonance imaging (MRI) contrast agent for dynamic contrast-enhanced (DCE) MRI of tumors. Materials and Methods A previously repor
Autor:
Weiran Cheng, Joris Nofiele, Xiao-an Zhang, Timothy J. Scholl, Kiran Beera, Francisco Martinez, Hai-Ling Margaret Cheng, Inga E. Haedicke
Publikováno v:
Journal of Medicinal Chemistry. 57:516-520
Mn(III) porphyrin (MnP) holds the promise of addressing the emerging challenges associated with Gd-based clinical MRI contrast agents (CAs), namely, Gd-related adverse effect and decreasing sensitivity at high clinical magnetic fields. Two complement
Publikováno v:
Journal of Magnetic Resonance Imaging. 40:1474-1480
Purpose To evaluate a new class of manganese porphyrins with tunable pharmacokinetics as potential gadolinium (Gd)-free T1 agents for contrast-enhanced magnetic resonance imaging (MRI). Materials and Methods Two new contrast agents, MnTCP and MnP2, w
Autor:
Inga E, Haedicke, Tan, Li, Yong Le K, Zhu, Francisco, Martinez, Amanda M, Hamilton, Donna H, Murrell, Joris T, Nofiele, Hai-Ling M, Cheng, Timothy J, Scholl, Paula J, Foster, Xiao-An, Zhang
Publikováno v:
Chemical Science
MnAMP, a cell-trappable pro-contrast agent gets enzymatically activated and accumulated intracellularly to provide a strong MRI signal for cell labeling.
Magnetic resonance imaging (MRI) is a preferred technique for noninvasively monitoring the
Magnetic resonance imaging (MRI) is a preferred technique for noninvasively monitoring the