Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Inga Duignan"'
Autor:
Nick Loizos, Rolf A. Brekken, Colleen Burns, Timothy Bailey, Jennifer Malaby, Inga Duignan, Michael Peyton, Jason E. Toombs, Michael T. Dellinger, Puja Gupta, David E. Gerber
PDF file, 156K, Species and target specificity of IMC-3G3 and 1E10.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::433fb0e5b3f734405f2853cb0aa6d4da
https://doi.org/10.1158/1535-7163.22497432
https://doi.org/10.1158/1535-7163.22497432
Autor:
Nick Loizos, Rolf A. Brekken, Colleen Burns, Timothy Bailey, Jennifer Malaby, Inga Duignan, Michael Peyton, Jason E. Toombs, Michael T. Dellinger, Puja Gupta, David E. Gerber
In lung cancer, platelet-derived growth factor receptor α (PDGFRα) is expressed frequently by tumor-associated stromal cells and by cancer cells in a subset of tumors. We sought to determine the effect of targeting stromal PDGFRα in preclinical lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::874c4025e37e3874f2ebebd8c1b83be5
https://doi.org/10.1158/1535-7163.c.6535614.v1
https://doi.org/10.1158/1535-7163.c.6535614.v1
Autor:
Nick Loizos, Rolf A. Brekken, Colleen Burns, Timothy Bailey, Jennifer Malaby, Inga Duignan, Michael Peyton, Jason E. Toombs, Michael T. Dellinger, Puja Gupta, David E. Gerber
PDF file, 46K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7225d085b5054d300fe6894dff981838
https://doi.org/10.1158/1535-7163.22497429
https://doi.org/10.1158/1535-7163.22497429
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 290:H1387-H1392
Diabetes mellitus is associated with an increased risk of vascular disease, with significant alterations in systemic endothelial progenitor cells (EPCs) and peripheral vascular function. To identify the contribution of the different vascular compartm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2fe340c413423b50012ca272c8fe8bb
https://doi.org/10.1152/ajpheart.00652.2005
https://doi.org/10.1152/ajpheart.00652.2005
Autor:
Jay M. Edelberg, Andrew Chin, Jingang Zheng, Munira Xaymardan, Jacquelyne M. Holm, Victoria L.T. Ballard, Inga Duignan, Dongqing Cai, Jonathan N. Bella
Publikováno v:
Physiological Genomics. 24:191-197
Aging is associated with shifts in autocrine and paracrine pathways in the cardiac vasculature that may contribute to the risk of cardiovascular disease in older persons. To elucidate the molecular basis of these changes in vivo, phage-display biopan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de07900fc9e045a7825e3ce9fa633df
https://doi.org/10.1152/physiolgenomics.00165.2005
https://doi.org/10.1152/physiolgenomics.00165.2005
Autor:
Andrew Chin, Victoria L.T. Ballard, Inga Duignan, Jacquelyne M. Holm, Munira Xaymardan, Jay M. Edelberg, Jingang Zheng
Publikováno v:
The Journal of Experimental Medicine
Pretreatment of rodent hearts with platelet-derived growth factor (PDGF)–AB decreases myocardial injury after coronary occlusion. However, PDGF-AB cardioprotection is diminished in older animals, suggesting that downstream elements mediating and/or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46cf666f27d1e77798d8fda0a4bfaeac
https://doi.org/10.1084/jem.20031639
https://doi.org/10.1084/jem.20031639
Autor:
Victoria L.T. Ballard, Andrew Chin, Jacquelyne M. Holm, Inga Duignan, Jay M. Edelberg, Ruby Choi, Arti Sharma, Katherine A. Hajjar, Shing-Chiu Wong
Publikováno v:
The FASEB Journal. 20:717-719
Microenvironmental cues mediate postnatal neovascularization via modulation of endothelial cell and bone marrow-derived endothelial progenitor cell (EPC) activity. Numerous signals regulate the activity of both of these cell types in response to vasc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::021b2d642d193ed997fceec514edf2b6
https://doi.org/10.1096/fj.05-5131fje
https://doi.org/10.1096/fj.05-5131fje
Autor:
Takashi Mikawa, Benedetta A. Pallante, Inga Duignan, Andrew Chin, Jay M. Edelberg, Daniel Okin, Michael Bressan
Publikováno v:
Circulation Research. 100
The mechanisms that govern the capacity of the bone marrow stem cells to generate cardiac myocytes are still unknown. Herein we demonstrate that the cardiomyogenic potential of bone marrow–derived Oct3/4 + /cKit +/− /CXCR4 +/− /CD34 − /Sca1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fde210a60f10c3401dda0542de1d6b3
https://doi.org/10.1161/01.res.0000253487.02398.85
https://doi.org/10.1161/01.res.0000253487.02398.85
Autor:
Victoria L.T. Ballard, Munira Xaymardan, Jacquelyne M. Holm, Jay M. Edelberg, Inga Duignan, Andrew Chin
Publikováno v:
The FASEB Journal. 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95fc33fafd0b2f6aefa5b09e97d85365
https://doi.org/10.1096/fasebj.20.4.a31-b
https://doi.org/10.1096/fasebj.20.4.a31-b
The development of new strategies to reduce the impact of heart disease in the aging population is an increasingly important public health issue. Indeed, although present clinical therapies have reduced the overall prevalence of cardiovascular diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd9e715c057eb097ab38266254e008e0
https://doi.org/10.1016/b978-012369391-4/50079-5
https://doi.org/10.1016/b978-012369391-4/50079-5