Zobrazeno 1 - 2
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pro vyhledávání: '"Infrastructure Nationale PHENOMIN, Institut Clinique De La Souris (ICS)"'
Autor:
Dickinson, Mary E, Flenniken, Ann M, Ji, Xiao, Teboul, Lydia, Wong, Michael D, White, Jacqueline K, Meehan, Terrence F, Weninger, Wolfgang J, Westerberg, Henrik, Adissu, Hibret, Baker, Candice N, Bower, Lynette, Brown, James M, Caddle, L Brianna, Chiani, Francesco, Clary, Dave, Cleak, James, Daly, Mark J, Denegre, James M, Doe, Brendan, Dolan, Mary E, Edie, Sarah M, Fuchs, Helmut, Gailus-Durner, Valerie, Galli, Antonella, Gambadoro, Alessia, Gallegos, Juan, Guo, Shiying, Horner, Neil R, Hsu, Chih-Wei, Johnson, Sara J, Kalaga, Sowmya, Keith, Lance C, Lanoue, Louise, Lawson, Thomas N, Lek, Monkol, Mark, Manuel, Marschall, Susan, Mason, Jeremy, McElwee, Melissa L, Newbigging, Susan, Nutter, Lauryl MJ, Peterson, Kevin A, Ramirez-Solis, Ramiro, Rowland, Douglas J, Ryder, Edward, Samocha, Kaitlin E, Seavitt, John R, Selloum, Mohammed, Szoke-Kovacs, Zsombor, Tamura, Masaru, Trainor, Amanda G, Tudose, Ilinca, Wakana, Shigeharu, Warren, Jonathan, Wendling, Olivia, West, David B, Wong, Leeyean, Yoshiki, Atsushi, International Mouse Phenotyping Consortium, Laboratory, Jackson, Infrastructure Nationale PHENOMIN, Institut Clinique De La Souris (ICS), Laboratories, Charles River, MRC Harwell, Toronto Centre For Phenogenomics, Wellcome Trust Sanger Institute, RIKEN BioResource Center, MacArthur, Daniel G, Tocchini-Valentini, Glauco P, Gao, Xiang, Flicek, Paul, Bradley, Allan, Skarnes, William C, Justice, Monica J, Parkinson, Helen E, Moore, Mark, Wells, Sara, Braun, Robert E, Svenson, Karen L, De Angelis, Martin Hrabe, Herault, Yann, Mohun, Tim, Mallon, Ann-Marie, Henkelman, R Mark, Brown, Steve DM, Adams, David J, Lloyd, KC Kent, McKerlie, Colin, Beaudet, Arthur L, Bućan, Maja, Murray, Stephen A
Publikováno v:
Nature, vol 537, iss 7621
Approximately one-third of all mammalian genes are essential for life. Phenotypes resulting from knockouts of these genes in mice have provided tremendous insight into gene function and congenital disorders. As part of the International Mouse Phenoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169e416fc7325a32ddbee0ebd8424d03
https://escholarship.org/uc/item/06t772m3
https://escholarship.org/uc/item/06t772m3
Autor:
Dickinson ME; Department of Molecular Physiology and Biophysics, Houston, Texas 77030, USA., Flenniken AM; The Toronto Centre for Phenogenomics, Toronto, Ontario M5T 3H7, Canada.; Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada., Ji X; Genomics and Computational Biology Program, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA., Teboul L; Medical Research Council Harwell (Mammalian Genetics Unit and Mary Lyon Centre), Harwell, Oxfordshire OX11 0RD, UK., Wong MD; The Toronto Centre for Phenogenomics, Toronto, Ontario M5T 3H7, Canada.; Mouse Imaging Centre, The Hospital for Sick Children, Toronto, Ontario M5T 3H7, Canada., White JK; The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Meehan TF; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK., Weninger WJ; Centre for Anatomy and Cell Biology, Medical University of Vienna, Vienna A-1090, Austria., Westerberg H; Medical Research Council Harwell (Mammalian Genetics Unit and Mary Lyon Centre), Harwell, Oxfordshire OX11 0RD, UK., Adissu H; The Toronto Centre for Phenogenomics, Toronto, Ontario M5T 3H7, Canada.; The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada., Baker CN; The Jackson Laboratory, Bar Harbor, Maine 04609, USA., Bower L; Mouse Biology Program, University of California, Davis, California 95618, USA., Brown JM; Medical Research Council Harwell (Mammalian Genetics Unit and Mary Lyon Centre), Harwell, Oxfordshire OX11 0RD, UK., Caddle LB; The Jackson Laboratory, Bar Harbor, Maine 04609, USA., Chiani F; Monterotondo Mouse Clinic, Italian National Research Council (CNR), Institute of Cell Biology and Neurobiology, Monterotondo Scalo I-00015, Italy., Clary D; Mouse Biology Program, University of California, Davis, California 95618, USA., Cleak J; Medical Research Council Harwell (Mammalian Genetics Unit and Mary Lyon Centre), Harwell, Oxfordshire OX11 0RD, UK., Daly MJ; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.; Program in Medical and Population Genetics, Broad Institute MIT and Harvard, Cambridge, Massachusetts 02142, USA., Denegre JM; The Jackson Laboratory, Bar Harbor, Maine 04609, USA., Doe B; The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Dolan ME; The Jackson Laboratory, Bar Harbor, Maine 04609, USA., Edie SM; The Jackson Laboratory, Bar Harbor, Maine 04609, USA., Fuchs H; Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Experimental Genetics and German Mouse Clinic, Neuherberg 85764, Germany., Gailus-Durner V; Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Experimental Genetics and German Mouse Clinic, Neuherberg 85764, Germany., Galli A; The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Gambadoro A; Monterotondo Mouse Clinic, Italian National Research Council (CNR), Institute of Cell Biology and Neurobiology, Monterotondo Scalo I-00015, Italy., Gallegos J; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Guo S; SKL of Pharmaceutical Biotechnology and Model Animal Research Center, Collaborative Innovation Center for Genetics and Development, Nanjing Biomedical Research Institute, Nanjing University, Nanjing 210061, China., Horner NR; Medical Research Council Harwell (Mammalian Genetics Unit and Mary Lyon Centre), Harwell, Oxfordshire OX11 0RD, UK., Hsu CW; Department of Molecular Physiology and Biophysics, Houston, Texas 77030, USA., Johnson SJ; Medical Research Council Harwell (Mammalian Genetics Unit and Mary Lyon Centre), Harwell, Oxfordshire OX11 0RD, UK., Kalaga S; Department of Molecular Physiology and Biophysics, Houston, Texas 77030, USA., Keith LC; Department of Molecular Physiology and Biophysics, Houston, Texas 77030, USA., Lanoue L; Mouse Biology Program, University of California, Davis, California 95618, USA., Lawson TN; Medical Research Council Harwell (Mammalian Genetics Unit and Mary Lyon Centre), Harwell, Oxfordshire OX11 0RD, UK., Lek M; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.; Program in Medical and Population Genetics, Broad Institute MIT and Harvard, Cambridge, Massachusetts 02142, USA., Mark M; Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS), et Institut de Génétique Biologie Moléculaire et Cellulaire (IGBMC) CNRS, INSERM, University of Strasbourg, Illkirch-Graffenstaden 67404, France., Marschall S; Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Experimental Genetics and German Mouse Clinic, Neuherberg 85764, Germany., Mason J; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK., McElwee ML; Department of Molecular Physiology and Biophysics, Houston, Texas 77030, USA., Newbigging S; The Toronto Centre for Phenogenomics, Toronto, Ontario M5T 3H7, Canada.; The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada., Nutter LM; The Toronto Centre for Phenogenomics, Toronto, Ontario M5T 3H7, Canada.; The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada., Peterson KA; The Jackson Laboratory, Bar Harbor, Maine 04609, USA., Ramirez-Solis R; The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Rowland DJ; Mouse Biology Program, University of California, Davis, California 95618, USA., Ryder E; The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Samocha KE; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.; Program in Medical and Population Genetics, Broad Institute MIT and Harvard, Cambridge, Massachusetts 02142, USA., Seavitt JR; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Selloum M; Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS), et Institut de Génétique Biologie Moléculaire et Cellulaire (IGBMC) CNRS, INSERM, University of Strasbourg, Illkirch-Graffenstaden 67404, France., Szoke-Kovacs Z; Medical Research Council Harwell (Mammalian Genetics Unit and Mary Lyon Centre), Harwell, Oxfordshire OX11 0RD, UK., Tamura M; RIKEN BioResource Center, Tsukuba, Ibaraki 305-0074, Japan., Trainor AG; Mouse Biology Program, University of California, Davis, California 95618, USA., Tudose I; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK., Wakana S; RIKEN BioResource Center, Tsukuba, Ibaraki 305-0074, Japan., Warren J; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK., Wendling O; Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS), et Institut de Génétique Biologie Moléculaire et Cellulaire (IGBMC) CNRS, INSERM, University of Strasbourg, Illkirch-Graffenstaden 67404, France., West DB; Children's Hospital Oakland Research Institute, Oakland, California 94609, USA., Wong L; Department of Molecular Physiology and Biophysics, Houston, Texas 77030, USA., Yoshiki A; RIKEN BioResource Center, Tsukuba, Ibaraki 305-0074, Japan., MacArthur DG; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.; Program in Medical and Population Genetics, Broad Institute MIT and Harvard, Cambridge, Massachusetts 02142, USA., Tocchini-Valentini GP; Monterotondo Mouse Clinic, Italian National Research Council (CNR), Institute of Cell Biology and Neurobiology, Monterotondo Scalo I-00015, Italy., Gao X; SKL of Pharmaceutical Biotechnology and Model Animal Research Center, Collaborative Innovation Center for Genetics and Development, Nanjing Biomedical Research Institute, Nanjing University, Nanjing 210061, China., Flicek P; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK., Bradley A; The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Skarnes WC; The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Justice MJ; The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Parkinson HE; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK., Moore M; IMPC, San Anselmo, California 94960, USA., Wells S; Medical Research Council Harwell (Mammalian Genetics Unit and Mary Lyon Centre), Harwell, Oxfordshire OX11 0RD, UK., Braun RE; The Jackson Laboratory, Bar Harbor, Maine 04609, USA., Svenson KL; The Jackson Laboratory, Bar Harbor, Maine 04609, USA., de Angelis MH; Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Experimental Genetics and German Mouse Clinic, Neuherberg 85764, Germany.; Chair of Experimental Genetics, School of Life Science Weihenstephan, Technische Universität München, Freising 81675, Germany.; German Center for Diabetes Research (DZD), Neuherberg 85764, Germany., Herault Y; Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris (ICS), et Institut de Génétique Biologie Moléculaire et Cellulaire (IGBMC) CNRS, INSERM, University of Strasbourg, Illkirch-Graffenstaden 67404, France., Mohun T; The Francis Crick Institute Mill Hill Laboratory, The Ridgeway, Mill Hill, London NW1 1AT, UK., Mallon AM; Medical Research Council Harwell (Mammalian Genetics Unit and Mary Lyon Centre), Harwell, Oxfordshire OX11 0RD, UK., Henkelman RM; The Toronto Centre for Phenogenomics, Toronto, Ontario M5T 3H7, Canada.; Mouse Imaging Centre, The Hospital for Sick Children, Toronto, Ontario M5T 3H7, Canada., Brown SD; Medical Research Council Harwell (Mammalian Genetics Unit and Mary Lyon Centre), Harwell, Oxfordshire OX11 0RD, UK., Adams DJ; The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Lloyd KC; Mouse Biology Program, University of California, Davis, California 95618, USA., McKerlie C; The Toronto Centre for Phenogenomics, Toronto, Ontario M5T 3H7, Canada.; The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada., Beaudet AL; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA., Bućan M; Departments of Genetics and Psychiatry, Perlman School of Medicine, University of Pennsylvania, Philadelphia Pennsylvania 19104, USA., Murray SA; The Jackson Laboratory, Bar Harbor, Maine 04609, USA.
Publikováno v:
Nature [Nature] 2016 Sep 22; Vol. 537 (7621), pp. 508-514. Date of Electronic Publication: 2016 Sep 14.
