Zobrazeno 1 - 10
of 2 171
pro vyhledávání: '"Inferior olive"'
Autor:
Rene Miedema, Christos Strydis
Publikováno v:
Frontiers in Neuroinformatics, Vol 18 (2024)
IntroductionIn-silico simulations are a powerful tool in modern neuroscience for enhancing our understanding of complex brain systems at various physiological levels. To model biologically realistic and detailed systems, an ideal simulation platform
Externí odkaz:
https://doaj.org/article/91cf1a4c41084e51b2cc69acfa6f8751
Autor:
Sebastián Loyola, Tycho M Hoogland, Hugo Hoedemaker, Vincenzo Romano, Mario Negrello, Chris I De Zeeuw
Publikováno v:
eLife, Vol 12 (2023)
The inferior olive provides the climbing fibers to Purkinje cells in the cerebellar cortex, where they elicit all-or-none complex spikes and control major forms of plasticity. Given their important role in both short-term and long-term coordination o
Externí odkaz:
https://doaj.org/article/fe408a7b3a35414d8395bc5dbc4167b9
Akademický článek
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Autor:
Joan S. Baizer, Sandra F. Witelson
Publikováno v:
Frontiers in Neuroanatomy, Vol 17 (2023)
IntroductionIt is commonly thought that while the organization of the cerebral cortex changes dramatically over evolution, the organization of the brainstem is conserved across species. It is further assumed that, as in other species, brainstem organ
Externí odkaz:
https://doaj.org/article/c40f249b9b7b41019bc14f264f7d3b63
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Nicotine induces kinetic tremor, which resembles pharmacological features of essential tremors, via activating the inferior olive (IO) neurons. Since nicotine is known to enhance dopamine release by stimulating α4β2 and/or α6 nACh receptors, we ex
Externí odkaz:
https://doaj.org/article/4c89cfb97b254e9fb0d8298996d4b546
Publikováno v:
Journal of Integrative Neuroscience, Vol 19, Iss 3, Pp 507-511 (2020)
Transsynaptic degeneration in the cerebellum and brainstem may give rise to a rare neurological condition with various clinical manifestations, namely hypertrophic olivary degeneration. The classical manifestations of hypertrophic olivary degeneratio
Externí odkaz:
https://doaj.org/article/f1d4b66ab0f043af95c1ad968e7ca800
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Adeno-associated viral (AAV) vectors, used as vehicles for gene transfer into the brain, are a versatile and powerful tool of modern neuroscience that allow identifying specific neuronal populations, monitoring and modulating their activity. For cons
Externí odkaz:
https://doaj.org/article/929b174d658a488aba05af84669ab049
Publikováno v:
Cell Reports, Vol 37, Iss 11, Pp 110116- (2021)
Summary: The brain selectively allocates attention from a continuous stream of sensory input. This process is typically attributed to computations in distinct regions of the forebrain and midbrain. Here, we explore whether cerebellar Purkinje cells e
Externí odkaz:
https://doaj.org/article/79e4c348332a4279964b6290c9871e42
Autor:
Joan S. Baizer
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 15 (2021)
The brainstem includes many nuclei and fiber tracts that mediate a wide range of functions. Data from two parallel approaches to the study of autistic spectrum disorder (ASD) implicate many brainstem structures. The first approach is to identify the
Externí odkaz:
https://doaj.org/article/9b0728955b624c78a69393a54fb5ef6c
Publikováno v:
eLife, Vol 10 (2021)
The cerebellum consists of parallel circuit modules that contribute to diverse behaviors, spanning motor to cognitive. Recent work employing cell-type-specific tracing has identified circumscribed output channels of the cerebellar nuclei (CbN) that c
Externí odkaz:
https://doaj.org/article/b8d0c06216904f2ba19207a0ca8fa0cf