Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Infectious Diseases/Urological Infections"'
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001187 (2010)
PLoS Pathogens
PLoS Pathogens
Murine models of urinary tract infection (UTI) have provided substantial data identifying uropathogenic E. coli (UPEC) virulence factors and assessing their expression in vivo. However, it is unclear how gene expression in these animal models compare
Autor:
Rebecca, Drake
Publikováno v:
PLoS ONE
Background Polymorphisms affecting Toll-like receptor (TLR) structure appear to be rare, as would be expected due to their essential coordinator role in innate immunity. Here, we assess variation in TLR4 expression, rather than structure, as a mechan
Autor:
Milan Chromek, Matthew George Chapman, Petra Lüthje, Xiaoda Wang, Ylva Kai-Larsen, Åsa Holm, Jan Johansson, Lavinia Kádas, Birgitta Agerberth, Kjell Olof Hedlund, Ute Römling, Stefan H. Jacobson, Verena Peters, Annelie Brauner
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 6, Iss 7, p e1001010 (2010)
PLoS Pathogens, Vol 6, Iss 7, p e1001010 (2010)
Bacterial growth in multicellular communities, or biofilms, offers many potential advantages over single-cell growth, including resistance to antimicrobial factors. Here we describe the interaction between the biofilm-promoting components curli fimbr
Autor:
Patrick C. Seed, Carlos C. Goller
Publikováno v:
PLoS ONE
PLoS ONE, Vol 5, Iss 7, p e11642 (2010)
PLoS ONE, Vol 5, Iss 7, p e11642 (2010)
Rising antibiotic resistance among Escherichia coli, the leading cause of urinary tract infections (UTIs), has placed a new focus on molecular pathogenesis studies, aiming to identify new therapeutic targets. Anti-virulence agents are attractive as c
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 3, p e1000723 (2010)
PLoS Computational Biology
PLoS Computational Biology
Uropathogenic Escherichia coli (UPEC) represent the predominant cause of urinary tract infections (UTIs). A key UPEC molecular virulence mechanism is type 1 fimbriae, whose expression is controlled by the orientation of an invertible chromosomal DNA
Autor:
Jaklien C. Leemans, Sandrine Florquin, Johannes Roth, Mark C. Dessing, Chris M. van der Loos, Gwendoline J. D. Teske, Thomas J. Vogl, Tom van der Poll, Nike Claessen, Loes M. Butter
Publikováno v:
PLoS ONE, 5(10). Public Library of Science
PLoS ONE
PLoS ONE, Vol 5, Iss 10, p e13394 (2010)
PLoS ONE
PLoS ONE, Vol 5, Iss 10, p e13394 (2010)
BACKGROUND: Inflammation is commonly followed by the release of endogenous proteins called danger associated molecular patterns (DAMPs) that are able to warn the host for eminent danger. S100A8/A9 subunits are DAMPs that belong to the S100 family of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c547cd6076bf79c7c387b9857481b03e
https://doi.org/10.1371/journal.pone.0013394
https://doi.org/10.1371/journal.pone.0013394
Autor:
Ulf Jodal, Petter Storm, Sebastian Rämisch, Nataliya Lutay, Bryndis Ragnarsdottir, Ahmed Al Hadad, Ulrich Dobrindt, Alexander Urbano, Catharina Svanborg, Ellaine Salvador, Klas Jönsson, Hans Fischer, Diana Karpman, Manisha Yadav
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 6, Iss 9, p e1001109 (2010)
PLoS Pathogens; 6(9), pp 1-17 (2010)
PLoS Pathogens, Vol 6, Iss 9, p e1001109 (2010)
PLoS Pathogens; 6(9), pp 1-17 (2010)
The mucosal immune system identifies and fights invading pathogens, while allowing non-pathogenic organisms to persist. Mechanisms of pathogen/non-pathogen discrimination are poorly understood, as is the contribution of human genetic variation in dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be6ec20691a343b61d639f098126544
http://lup.lub.lu.se/record/1711502
http://lup.lub.lu.se/record/1711502
Autor:
Paul Keim, Jolene Bowers, Jacques Ravel, Kristine E. Johnson, Matthew K. Lau, Maria J. Wawer, Cindy M. Liu, David Serwadda, Ronald H. Gray, Lance B. Price, Maliha Aziz
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8422 (2010)
PLoS ONE
PLoS ONE
Background Circumcision is associated with significant reductions in HIV, HSV-2 and HPV infections among men and significant reductions in bacterial vaginosis among their female partners. Methodology/Principal Findings We assessed the penile (coronal
Publikováno v:
PLoS Pathogens, Vol 5, Iss 12, p e1000697 (2009)
PLoS Pathogens
PLoS Pathogens
Extraintestinal pathogenic E. coli (ExPEC) cause an array of diseases, including sepsis, neonatal meningitis, and urinary tract infections. Many putative virulence factors that might modulate ExPEC pathogenesis have been identified through sequencing
Autor:
Sue Li, Marta Janer, Hongwei Wang, Ann E. Stapleton, Thomas R. Hawn, Walter E. Stamm, Alan Aderem, Thomas M. Hooton, Lue Ping Zhao, Delia Scholes
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8300 (2009)
PLoS ONE
PLoS ONE
BACKGROUND:Although several studies suggest that genetic factors are associated with human UTI susceptibility, the role of DNA variation in regulating early in vivo urine inflammatory responses has not been fully examined. We examined whether candida